Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jean-Baptiste Cazier"'
Autor:
Mark Hull, Richard Houlston, Simon Bach, Inke Näthke, John Burn, Viktor Koelzer, Robert JC Steele, Annie Anderson, Vicky Goh, Jean-Baptiste Cazier, Kevin Monahan, Gina Brown, Daniel Hochhauser, Julian Downward, Anne Thomas, Richard Wilson, Angus McNair, Ultan McDermott, Leslie Samuel, Sam Ahmedzai, David Cunningham, Richard Adams, Marco Gerlinger, David Brewster
Publikováno v:
Lawler, M, Alsina, D, Adams, R A, Anderson, A S, Brown, G, Fearnhead, N S, Fenwick, S W, Halloran, S P, Hochhauser, D, Hull, M A, Koelzer, V H, McNair, A G K, Monahan, K J, Näthke, I, Norton, C, Novelli, M R, Steele, R J C, Thomas, A L, Wilde, L M, Wilson, R H, Tomlinson, I 2018, ' Critical research gaps and recommendations to inform research prioritisation for more effective prevention and improved outcomes in colorectal cancer ', Gut, vol. 67, no. 1, pp. 179-193 . https://doi.org/10.1136/gutjnl-2017-315333
Lawler, M, Alsina, D, Adams, R A, Anderson, A S, Brown, G, Fearnhead, N S, Fenwick, S W, Halloran, S P, Hochhauser, D, Hull, M A, Koelzer, V H, McNair, A G K, Monahan, K J, Näthke, I, Norton, C, Novelli, M R, Steele, R J C, Thomas, A L, Wilde, L M, Wilson, R H, Tomlinson, I & Bowel Cancer UK Critical Research Gaps in Colorectal Cancer Initiative 2018, ' Critical research gaps and recommendations to inform research prioritisation for more effective prevention and improved outcomes in colorectal cancer ', Gut, vol. 67, no. 1, pp. 179-193 . https://doi.org/10.1136/gutjnl-2017-315333
Gut
Lawler, M, Alsina, D, Adams, R A, Anderson, A S, Brown, G, Fearnhead, N S, Fenwick, S W, Halloran, S P, Hochhauser, D, Hull, M A, Koelzer, V H, Mcnair, A G K, Monahan, K J, Näthke, I, Norton, C, Novelli, M R, Steele, R J C, Thomas, A L, Wilde, L M, Wilson, R H & Tomlinson, I 2018, ' Critical research gaps and recommendations to inform research prioritisation for more effective prevention and improved outcomes in colorectal cancer ', Gut, vol. 67, no. 1, pp. 179-193 . https://doi.org/10.1136/gutjnl-2017-315333
Lawler, M, Alsina, D, Adams, R A, Anderson, A S, Brown, G, Fearnhead, N S, Fenwick, S W, Halloran, S P, Hochhauser, D, Hull, M A, Koelzer, V H, McNair, A G K, Monahan, K J, Näthke, I, Norton, C, Novelli, M R, Steele, R J C, Thomas, A L, Wilde, L M, Wilson, R H, Tomlinson, I & Bowel Cancer UK Critical Research Gaps in Colorectal Cancer Initiative 2018, ' Critical research gaps and recommendations to inform research prioritisation for more effective prevention and improved outcomes in colorectal cancer ', Gut, vol. 67, no. 1, pp. 179-193 . https://doi.org/10.1136/gutjnl-2017-315333
Gut
Lawler, M, Alsina, D, Adams, R A, Anderson, A S, Brown, G, Fearnhead, N S, Fenwick, S W, Halloran, S P, Hochhauser, D, Hull, M A, Koelzer, V H, Mcnair, A G K, Monahan, K J, Näthke, I, Norton, C, Novelli, M R, Steele, R J C, Thomas, A L, Wilde, L M, Wilson, R H & Tomlinson, I 2018, ' Critical research gaps and recommendations to inform research prioritisation for more effective prevention and improved outcomes in colorectal cancer ', Gut, vol. 67, no. 1, pp. 179-193 . https://doi.org/10.1136/gutjnl-2017-315333
ObjectiveColorectal cancer (CRC) leads to significant morbidity/mortality worldwide. Defining critical research gaps (RG), their prioritisation and resolution, could improve patient outcomes.DesignRG analysis was conducted by a multidisciplinary pane
Autor:
Elena Gallardo, Luis Bujanda, Rosa M. Xicola, Antoni Castells, María I. García, Lucía Cortejoso, Montserrat Andreu, Laia Paré, Josep-Maria Reñé, Victor Moreno, Elisabeth Guino, Ceres Fernandez-Rozadilla, David Páez, Victoria Gonzalo, Clara Ruiz-Ponte, Montserrat Baiget, Jean-Baptiste Cazier, Alejandro Brea-Fernández, Xavier Bessa, Luis A. López-Fernández, María Jesús Lamas, Xavier Llor, Dolors Gonzalez, Claire Palles, Sonia Candamio, R. Jover, Sergi Castellví-Bel, Luis Rodrigo, Goretti Duran, Marta Crous-Bou, Rafael López, Ian Tomlinson, Angel Carracedo
Publikováno v:
PHARMACOGENOMICS JOURNAL
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
The development of genotyping technologies has allowed for wider screening for inherited causes of variable outcomes following drug administration. We have performed a genome-wide association study (GWAS) on 221 colorectal cancer (CRC) patients that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfee7bb772359573fde439ee1248eb3e
https://ora.ox.ac.uk/objects/uuid:33723795-f3a8-4604-84a3-ecfe2d1726be
https://ora.ox.ac.uk/objects/uuid:33723795-f3a8-4604-84a3-ecfe2d1726be
Autor:
Christopher Yau, Jean-Baptiste Cazier, Oliver M. Sieber, David Propper, Neel Sengupta, Nirosha Suraweera, Anuratha Sakthianandeswaren, Mohamed A. Thaha, Guadalupe Polanco-Echeverry, Shafi Ahmed, Cecilia Lai, Roger Feakins, Anil Ghosh, Dmitri Mouradov, Andrew Silver, Peter Gibbs, Sina Dorudi
Publikováno v:
Europe PubMed Central
Molecular Cancer
Molecular Cancer, Vol 12, Iss 1, p 1 (2013)
Molecular Cancer
Molecular Cancer, Vol 12, Iss 1, p 1 (2013)
Background Prevalence of colorectal cancer (CRC) in the British Bangladeshi population (BAN) is low compared to British Caucasians (CAU). Genetic background may influence mutations and disease features. Methods We characterized the clinicopathologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0eed1176031c6d77fd06ad3511d98b1
https://ora.ox.ac.uk/objects/uuid:97c7bf4a-8c85-4379-b7f7-0c8c94be7a5c
https://ora.ox.ac.uk/objects/uuid:97c7bf4a-8c85-4379-b7f7-0c8c94be7a5c
Autor:
Peter Propping, Eamonn R. Maher, Richard S. Houlston, Hans K. Schackert, D. Timothy Bishop, Jean-Baptiste Cazier, Anneke Lucassen, Juul T. Wijnen, Zoe Kemp, Huw Thomas, Gabrielle S. Sellick, Luis G. Carvajal-Carmona, Steven J. Lubbe, Elke Holinski-Feder, Nils Rahner, Maggie Gorman, Ian Tomlinson, Emma Jaeger, Ella Barclay, Verena Steinke, Timm O. Goecke, Peter Broderick, D. Gareth Evans, Kate Sullivan, Tom van Wezel, Jayaram Vijayakrishnan, Emily L. Webb, Eli Papaemmanuil, Sarah L. Spain, Lynn Martin
Previously we have localized to chromosome 3q21-q24, a predisposition locus for colorectal cancer (CRC), through a genome-wide linkage screen (GWLS) of 69 families without familial adenomatous polyposis or hereditary non-polyposis CRC. To further inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb7aa2568e0e8173844867ecc3f26e4
https://ora.ox.ac.uk/objects/uuid:09a07608-f370-4e39-a64e-5173a57f2ce4
https://ora.ox.ac.uk/objects/uuid:09a07608-f370-4e39-a64e-5173a57f2ce4
Autor:
Lara Lipton, Amy Price, Enric Domingo, Trinidad Caldés, Gianluca Severi, Emma Jaeger, Sarah Fielding, Auli Karhu, José M. Ladero, Alan M. Pittman, David J. Kerr, Axel Walther, Mobshra Qureshi, Ian Tomlinson, Sergi Castellví-Bel, King Yip Cheng, Miguel de la Hoya, Wendy Wood, Emily L. Webb, John M. Luk, G Evans, Philip Twiss, Timothy Bishop, Hans Morreau, Steven Penegar, Pak C. Sham, Angel Carracedo, Melissa C. Southey, Eamonn R. Maher, Maria Chiara Di Bernardo, Sarah L. Spain, Julian Peto, Anneke Lucassen, Kari Hemminki, Lynn Martin, Richard Gray, Ian Chandler, Luis G. Carvajal-Carmona, Jean-Baptiste Cazier, Steven J. Lubbe, Kimberley Howarth, Richard S. Houlston, Graham G. Giles, Maggie Gorman, Kate Sullivan, Zoe Kemp, Pavel Vodicka, Judy W. C. Ho, Lauri A. Aaltonen, Clara Ruiz-Ponte, Jayaram Vijayakrishnan, Asta Försti, Huw Thomas, Alessio Naccarati, Peter Broderick, Juul T. Wijnen, Antoni Castells, Tom van Wezel, John L. Hopper, Iina Niittymäki, José A. G. Agúndez, Sari Tuupanen, Andrew Rowan, Ella Barclay
Publikováno v:
Human Molecular Genetics. 17:3720-3727
The common single-nucleotide polymorphism (SNP) rs3802842 at 11q23.1 has recently been reported to be associated with risk of colorectal cancer (CRC). To examine this association in detail we genotyped rs3802842 in eight independent case-control seri
Autor:
Sari Tuupanen, Melissa C. Southey, Ian Chandler, Enric Domingo, Paul D.P. Pharoah, Luis G. Carvajal-Carmona, D. Gareth Evans, Malcolm G. Dunlop, Trinidad Caldés, Graham G. Giles, Zoe Kemp, Harry Campbell, David J. Kerr, Alan M. Pittman, Eamonn R. Maher, D. Timothy Bishop, Jayaram Vijayakrishnan, Hans Morreau, Albert Tenesa, Asta Försti, Jean-Baptiste Cazier, Kimberley Howarth, Ella Barclay, Rebecca A. Barnetson, Tom van Wezel, Juul T. Wijnen, James G. D. Prendergast, Maggie Gorman, Julian Peto, Anneke Lucassen, Antoni Castells, Jochen Hampe, José A. G. Agúndez, Susan M. Farrington, Kate Sullivan, Henry Völzke, Richard Gray, Ulrich John, King Yip Cheng, Pavel Vodicka, Emma Jaeger, Peter Broderick, Judy W. C. Ho, Mobshra Qureshi, Lauri A. Aaltonen, Stephan Buch, Sarah Fielding, Sarah L. Spain, Lynn Martin, Andrew Rowan, Wendy Wood, Emily L. Webb, John M. Luk, Angel Carracedo, Clara Ruiz-Ponte, Alessio Naccarati, Steven J. Lubbe, Ian Tomlinson, Lara Lipton, John L. Hopper, Iina Niittymäki, Axel Walther, José M. Ladero, Pak C. Sham, Stefan Schreiber, Sergi Castellví-Bel, Miguel de la Hoya, Clemens Schafmayer, Gianluca Severi, Auli Karhu, Steven Penegar, Thibaud Koessler, Kari Hemminki, Richard S. Houlston, Huw Thomas
Publikováno v:
Nature Genetics. 40:623-630
To identify colorectal cancer (CRC) susceptibility alleles, we conducted a genome-wide association study. In phase 1, we genotyped 550,163 tagSNPs in 940 familial colorectal tumor cases (627 CRC, 313 high-risk adenoma) and 965 controls. In phase 2, w
Autor:
Hans Clevers, Lilian Vreede, C. Marleen Kets, Eugène T P Verwiel, Luis G. Carvajal-Carmona, Marjolijn J. L. Ligtenberg, Ramprasath Venkatachalam, Henner F. Farin, Kornelia Neveling, Lambertus A. Kiemeney, Ad Geurts van Kessel, Richarda M. de Voer, Monique van Asseldonk, Katja K.H. Aben, Roland P. Kuiper, Marc van de Wetering, Jean-Baptiste Cazier, Eveline J. Kamping, Nicoline Hoogerbrugge, Iris D. Nagtegaal, Robbert D.A. Weren, Ian Tomlinson, Hans K. Schackert
Publikováno v:
Journal of Pathology, 236, 2, pp. 155-164
Journal of Pathology, 236(2), 155. John Wiley and Sons Ltd
Journal of Pathology. John Wiley and Sons Ltd
The Journal of Pathology
The Journal of pathology, vol 236, iss 2
Journal of Pathology, 236, 155-164
Journal of Pathology, 236(2), 155. John Wiley and Sons Ltd
Journal of Pathology. John Wiley and Sons Ltd
The Journal of Pathology
The Journal of pathology, vol 236, iss 2
Journal of Pathology, 236, 155-164
Contains fulltext : 155369.pdf (Publisher’s version ) (Open Access) Heritable genetic variants can significantly affect the lifetime risk of developing cancer, including polyposis and colorectal cancer (CRC). Variants in genes currently known to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::006e07ab0d81a708f6f665014dc11997
https://hdl.handle.net/2066/155369
https://hdl.handle.net/2066/155369
Autor:
Jayaram Vijayakrishnan, Ella Barclay, Maggie Gorman, Julian Peto, Andrew Rowan, Peter Broderick, Richard S. Houlston, Zoe Kemp, Luis G. Carvajal-Carmona, Sarah L. Spain, Emily L. Webb, Enric Domingo, Ian Chandler, Kate Sullivan, Steven J. Lubbe, Alan M. Pittman, Kimberley Howarth, Elli Papaemmanuil, Lynn Martin, Richard Gray, Gabrielle S. Sellick, Oliver M. Sieber, Sarah Fielding, Wendy Wood, Emma Jaeger, David J. Kerr, Steven Penegar, Ian Tomlinson, Jean-Baptiste Cazier, Mobshra Qureshi, Ana Teixeira
Publikováno v:
Nature Genetics. 39:1315-1317
To identify risk variants for colorectal cancer (CRC), we conducted a genome-wide association study, genotyping 550,163 tag SNPs in 940 individuals with familial colorectal tumor (627 CRC, 313 advanced adenomas) and 965 controls. We evaluated selecte
Autor:
Rosa M. Xicola, Xavier Bessa, Xavier Llor, Juan Clofent, Luis G. Carvajal-Carmona, Angel Carracedo, Claire Palles, Rodrigo Jover, Montserrat Andreu, Ceres Fernandez-Rozadilla, Ian Tomlinson, Montserrat Baiget, Antoni Castells, Sergi Castellví-Bel, Jean-Baptiste Cazier, María Jesús Lamas, Dolors Gonzalez, Luis A. López-Fernández, Victor Moreno, Alejandro Brea-Fernández, Luis Bujanda, Clara Ruiz-Ponte, Anna Abulí
Publikováno v:
BMC genomics, vol 14, iss 1
RUNA. Repositorio da Consellería de Sanidade e Sergas
Servizo Galego de Saúde (SERGAS)
Addi. Archivo Digital para la Docencia y la Investigación
instname
Recercat. Dipósit de la Recerca de Catalunya
BMC Genomics
BMC GENOMICS
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Dipòsit Digital de la UB
Universidad de Barcelona
RUNA. Repositorio da Consellería de Sanidade e Sergas
Servizo Galego de Saúde (SERGAS)
Addi. Archivo Digital para la Docencia y la Investigación
instname
Recercat. Dipósit de la Recerca de Catalunya
BMC Genomics
BMC GENOMICS
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Dipòsit Digital de la UB
Universidad de Barcelona
Background: Colorectal cancer (CRC) is a disease of complex aetiology, with much of the expected inherited risk being due to several common low risk variants. Genome-Wide Association Studies (GWAS) have identified 20 CRC risk variants. Nevertheless,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bf4bc4b6080228a9f39d00c529bc1b5
https://escholarship.org/uc/item/9z6163kh
https://escholarship.org/uc/item/9z6163kh
Autor:
Malcolm G. Dunlop, Richard S. Houlston, Ian Tomlinson, Christopher Holmes, Joanna L. Davies, Jean-Baptiste Cazier
Publikováno v:
Davies, J L, Cazier, J-B, Dunlop, M G, Houlston, R S, Tomlinson, I P & Holmes, C C 2012, ' A Novel Test for Gene-Ancestry Interactions in Genome-Wide Association Data ', PLoS ONE, vol. 7, no. 12, ARTN e48687 . https://doi.org/10.1371/journal.pone.0048687
PLoS ONE, Vol 7, Iss 12, p e48687 (2012)
PLoS ONE
PLoS ONE, Vol 7, Iss 12, p e48687 (2012)
PLoS ONE
Genome-wide association study (GWAS) data on a disease are increasingly available from multiple related populations. In this scenario, meta-analyses can improve power to detect homogeneous genetic associations, but if there exist ancestry-specific ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f6132d73a1595ff118b423d86476560
https://www.pure.ed.ac.uk/ws/files/8232535/A_Novel_Test_for_Gene_Ancestry_Interactions_in_Genome_Wide_Association_Data.pdf
https://www.pure.ed.ac.uk/ws/files/8232535/A_Novel_Test_for_Gene_Ancestry_Interactions_in_Genome_Wide_Association_Data.pdf