Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Keun-Wook Lee"'
Autor:
Hyun Jung Lee, Kui-Jin Kim, Ji Hea Sung, Milang Nam, Koung Jin Suh, Ji-Won Kim, Se Hyun Kim, Jin Won Kim, Yu Jung Kim, Keun-Wook Lee, Jong Seok Lee, Jee Hyun Kim
Publikováno v:
Cancers, Vol 12, Iss 9, p 2500 (2020)
Targeting cell cycle regulation in colorectal cancer has not been fully evaluated. We investigated the efficacy of the CDK4/6 inhibitor, abemaciclib, and confirmed a synergistic interaction for PI3K p110α and CDK dual inhibition in colorectal cancer
Externí odkaz:
https://doaj.org/article/9efcb04f70f348ca90545afc62f2cc4c
Autor:
Kui-Jin Kim, Soo Mee Bang, Yu Jung Kim, Milang Nam, Ji Won Kim, Jin Won Kim, Ji Hea Sung, Ju Hyun Lee, Hyejoo Park, Jee Hyun Kim, Koung Jin Suh, Sang-A Kim, Eun Hee Jung, Ji Yun Lee, Jong Seok Lee, Keun-Wook Lee, Jeong Ok Lee, Se Hyun Kim
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 148:2995-3005
PURPOSE Recent evidence has highlighted the role of hepatocyte growth factor (HGF) as a putative biomarker to predict EGFR inhibitor resistance. This study investigated the impact of plasma HGF levels on EGFR inhibition and the counter effect of MET
Autor:
Ji Yeon Baek, Young Suk Park, Sang-Hee Cho, Tae Won Kim, You Jin Chun, Joong Bae Ahn, Minkyu Jung, Keun Wook Lee, Seong Geun Kim, Seung Hoon Beom, Chong Woo Chu, Soojung Hong, Sang Joon Shin
Publikováno v:
Clinical Colorectal Cancer. 19:e140-e150
Introduction Whether patients with resectable colorectal liver metastases (CRLM) gain a survival benefit from perioperative chemotherapy remains controversial. The benefit of including bevacizumab in chemotherapy also remains unclear. Material and Me
Publikováno v:
Anticancer Research. 40:2171-2177
Background/aim To develop a nomogram for predicting the pathological tumor response to preoperative chemoradiotherapy (CRT) for locally advanced rectal cancer based on pre-treatment magnetic resonance imaging (MRI) and blood test characteristics. Pat
Autor:
Beodeul Kang, Sung Soun Hur, Soo-Mee Bang, Ji Won Kim, Jee Hyun Kim, Se Hyun Kim, Y. Kim, Jin Won Kim, Keun-Wook Lee, Grace S. Ahn, Hak Ro Kim, Jeong Ok Lee, Jong Seok Lee
Publikováno v:
Annals of Palliative Medicine. 9:216-223
BACKGROUND Acute palliative care unit (APCU) is a novel inpatient program in a tertiary cancer center that provides aggressive symptom management and assists with the transition to hospice. However, patients often die in the APCU before successfully
Autor:
Keun Wook Lee, Joo Ho Lee, Byung Hee Kang, Hye Seung Lee, Jae Sung Kim, Sung Bum Kang, Changhoon Song, Eui Kyu Chie
Publikováno v:
In Vivo
Background/aim This study aimed to analyze the correlation between microsatellite instability (MSI) and inflammatory markers during neoadjuvant CRT in rectal cancer and its influence on prognosis. Patients and methods A total of 549 patients with loc
Autor:
Sun Young Kim, Chang Sik Yu, Jong Hoon Kim, Ji Sung Lee, Tae-You Kim, Jeong Eun Kim, Ji Yeon Baek, Joon Oh Park, Seong Hyeon Yun, Kyung Hae Jung, Joong Bae Ahn, Keun Wook Lee, Byung-Ho Nam, Kyu Pyo Kim, Young Suk Park, Seok Byung Lim, Hee Chul Park, Jin-Hong Park, Yong Sang Hong, Jin Cheon Kim, Tae Won Kim
Publikováno v:
Journal of Clinical Oncology. 37:3111-3123
PURPOSE We evaluated the role of oxaliplatin as adjuvant chemotherapy in patients with rectal cancer who received preoperative chemoradiotherapy (CRT) with fluoropyrimidine monotherapy and total mesorectal excision (TME). METHODS The ADORE trial (adj
Autor:
Bo-Kyoung Kim, Tae Won Kim, Seong-Jin Kim, Chan Young Ock, Ki Baik Hahm, Keun-Wook Lee, Sunjin Hwang, Joong Bae Ahn, Bitna Oh, Young Suk Park, Hyejoo Park, Jiyeon Ryu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundThe expression of PD-L1 and tumor-infiltrating CD8 T cells were reported to have a decisive effect on the immunotherapy response (PMID: 26819449). Microsatellite stable (MSS) metastatic colorectal cancer (mCRC) shows a limited clinical bene
Autor:
Chan Young Ock, Keun-Wook Lee, Bitna Oh, Gahee Park, Young Suk Park, Ki Baik Hahm, Kyunghyun Paeng, Joong Bae Ahn, Bo-Kyoung Kim, Sunjin Hwang, Tae Won Kim, Jiyeon Ryu, Seong-Jin Kim, Hyejoo Park
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundPreviously, we presented a promising anti-tumor efficacy (ORR: 16%, mOS: 15.8 months, RECIST) of the combination of vactosertib, a potent and selective TGF-β receptor I, and pembrolizumab (vac+pem) in patients with microsatellite stable me
Autor:
Xiang Lin Yuan, Kei Muro, Satoshi Morita, Masahito Kotaka, Keun Wook Lee, Joong Bae Ahn, Sang-Hee Cho, Young Suk Park, Dong Sheng Zhang, Tomohiro Nishina, Wei Jia Fang, Ying Yuan, Hiroshi Matsuoka, Masato Nakamura, Satoru Iwasa, Li Bai, Yong Sang Hong, Junichi Sakamoto, Sae-Won Han, Tae Won Kim, Yasuhide Yamada
Publikováno v:
Cancer Science
The phase III AXEPT study showed the noninferiority of modified capecitabine plus irinotecan (mXELIRI) with or without bevacizumab relative to fluorouracil, leucovorin, and irinotecan (FOLFIRI) with or without bevacizumab as a second‐line treatment