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pro vyhledávání: '"Kalai Selvi Shanmugam"'
Autor:
Michael Hoffmeister, Hermann Brenner, Kalai Selvi Shanmugam, Barbara Burwinkel, Jenny Chang-Claude
Publikováno v:
Carcinogenesis. 28:1914-1917
The Wnt-beta-catenin pathway plays a central role in colorectal tumorigenesis. Frizzled-related protein (FRZB, also termed secreted frizzled-related protein 3, sFRP3) antagonizes the signaling of wingless (Wnt) ligands through the frizzled membrane-b
Autor:
Barbara Burwinkel, Bernd Frank, Hermann Brenner, Lars Beckmann, Kari Hemminki, Michael Hoffmeister, Jenny Chang-Claude, Kalai Selvi Shanmugam
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 15:2002-2005
The tumor necrosis factor–related apoptosis-inducing ligand receptor modulates apoptotic response by binding to the proapoptotic death receptor 4 (DR4). Perturbed apoptosis due to missense alterations in the candidate tumor suppressor gene DR4 lead