Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Vivianna, M Van Deerlin"'
Autor:
Daniel, Weintraub, Marijan, Posavi, Pierre, Fontanillas, Thomas F, Tropea, Eugenia, Mamikonyan, Eunran, Suh, John Q, Trojanowski, Paul, Cannon, Vivianna M, Van Deerlin, Alice S, Chen-Plotkin
Publikováno v:
Annals of Clinical and Translational Neurology. 9:936-949
To develop a clinico-genetic predictor of impulse control disorder (ICD) risk in Parkinson's disease (PD).In 5770 individuals from three PD cohorts (the 23andMe, Inc.; the University of Pennsylvania [UPenn]; and the Parkinson's Progression Markers In
Autor:
Nabila Dahodwala, Pedro Gonzalez-Alegre, Vivianna M. Van Deerlin, Howard I. Hurtig, Rizwan S. Akhtar, Andres Deik, EunRan Suh, Mary Ann Thenganatt, Alice Chen-Plotkin, Noah Han, Allison W. Willis, Jacqueline Rick, Andrew Siderowf, Noor Amari, Daniel Weintraub, Meredith Spindler, Matthew B. Stern, Thomas F. Tropea
Publikováno v:
J Parkinsons Dis
Background: Observational studies in Parkinson’s disease (PD) have focused on relatively small numbers of research participants who are studied extensively. The Molecular Integration in Neurological Diagnosis Initiative at the University of Pennsyl
Autor:
Claire Peterson, Vivianna M. Van Deerlin, Sharon X. Xie, EunRah Suh, Lucia A. A. Giannini, Katya Raskovsky, John Q. Trojanowski, Murray Grossman, David J. Irwin, Edward B. Lee, Lauren Massimo, Daniel T. Ohm, David A. Wolk, Corey T. McMillan
Publikováno v:
Acta neuropathologica communications, 9(1):30. BioMed Central Ltd.
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-19 (2021)
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-19 (2021)
Frontotemporal lobar degeneration proteinopathies with tau inclusions (FTLD-Tau) or TDP-43 inclusions (FTLD-TDP) are associated with clinically similar phenotypes. However, these disparate proteinopathies likely differ in cellular severity and region
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39479628f0907bcfa558e54087f7ce00
https://pure.eur.nl/en/publications/d3f19058-4e79-40d5-a6c8-b6ba85859348
https://pure.eur.nl/en/publications/d3f19058-4e79-40d5-a6c8-b6ba85859348
Autor:
Panpan Zhang, Peter T. Nelson, John Q. Trojanowski, Sharon X. Xie, EunRan Suh, Sílvia Porta, Justin M. Barber, Gregory A. Jicha, Edward B. Lee, John L. Robinson, Virginia M.-Y. Lee, Filip G. Garrett, Erin L. Abner, Vivianna M. Van Deerlin
Publikováno v:
Brain
TAR-DNA binding protein-43 (TDP-43) proteinopathy is seen in multiple brain diseases. A standardized terminology was recommended recently for common age-related TDP-43 proteinopathy: limbic-predominant, age-related TDP-43 encephalopathy (LATE) and th
Autor:
Lauren Elman, Edward B. Lee, Travis L. Unger, Defne A. Amado, John L. Robinson, John Q. Trojanowski, Vivianna M. Van Deerlin, Fei Mao, Virginia M.-Y. Lee, Alice Chen-Plotkin, Marijan Posavi, David A. Wolk, Murray Grossman, Sílvia Porta
Publikováno v:
Acta Neuropathol
The neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration with TAR DNA-binding protein-43 (TDP-43) inclusions (FTLD-TDP) share the neuropathological hallmark of aggregates of TDP-43. However, factors gov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d47ed414a746c385ba4d8d6261b9b960
https://europepmc.org/articles/PMC8812793/
https://europepmc.org/articles/PMC8812793/
Autor:
Nigel J. Cairns, David J. Stone, Tamas Revesz, Rita Guerreiro, Janice L. Holton, Jose Bras, Andrew J. Lees, Tanis J. Ferman, Afina W. Lemstra, Eliezer Masliah, Pentti J. Tienari, Pau Pastor, Ronald C. Petersen, Geidy E. Serrano, Celia Kun-Rodrigues, Elisabet Londos, Henrik Zetterberg, Dena G. Hernandez, John C. Morris, Tatiana Orme, Andrew B. Singleton, Owen A. Ross, Ekaterina Rogaeva, Thomas G. Beach, Karen Marder, Claire Troakes, Tammaryn Lashley, Kevin Morgan, Peter St George-Hyslop, Suzanne Lesage, Laura Parkkinen, Olaf Ansorge, Dennis W. Dickson, Glenda M. Halliday, John Q. Trojanowski, Liisa Myllykangas, Lorraine N. Clark, Isabel Santana, Neill R. Graff-Radford, Brad F. Boeve, Safa Al-Sarraj, Douglas Galasko, Minna Oinas, Vivianna M. Van Deerlin, Yaroslau Compta, John Hardy, Valentina Escott-Price, Lawrence S. Honig, Claire E. Shepherd, David M. A. Mann, Stuart Pickering-Brown, Lee Darwent
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-11 (2020)
Orme, T, Hernandez, D, Ross, O A, Kun-Rodrigues, C, Darwent, L, Shepherd, C E, Parkkinen, L, Ansorge, O, Clark, L, Honig, L S, Marder, K, Lemstra, A, Rogaeva, E, St George-Hyslop, P, Londos, E, Zetterberg, H, Morgan, K, Troakes, C, Al-Sarraj, S, Lashley, T, Holton, J, Compta, Y, Van Deerlin, V, Trojanowski, J Q, Serrano, G E, Beach, T G, Lesage, S, Galasko, D, Masliah, E, Santana, I, Pastor, P, Tienari, P J, Myllykangas, L, Oinas, M, Revesz, T, Lees, A, Boeve, B F, Petersen, R C, Ferman, T J, Escott-Price, V, Graff-Radford, N, Cairns, N J, Morris, J C, Pickering-Brown, S, Mann, D, Halliday, G, Stone, D J, Dickson, D W, Hardy, J, Singleton, A, Guerreiro, R & Bras, J 2020, ' Analysis of neurodegenerative disease-causing genes in dementia with Lewy bodies ', Acta Neuropathologica Communinications, vol. 8, no. 1, 5, pp. 5 . https://doi.org/10.1186/s40478-020-0879-z
Acta Neuropathologica Communications
Acta Neuropathologica Communinications, 8(1):5. BioMed Central
Universidad de Barcelona
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-11 (2020)
Orme, T, Hernandez, D, Ross, O A, Kun-Rodrigues, C, Darwent, L, Shepherd, C E, Parkkinen, L, Ansorge, O, Clark, L, Honig, L S, Marder, K, Lemstra, A, Rogaeva, E, St George-Hyslop, P, Londos, E, Zetterberg, H, Morgan, K, Troakes, C, Al-Sarraj, S, Lashley, T, Holton, J, Compta, Y, Van Deerlin, V, Trojanowski, J Q, Serrano, G E, Beach, T G, Lesage, S, Galasko, D, Masliah, E, Santana, I, Pastor, P, Tienari, P J, Myllykangas, L, Oinas, M, Revesz, T, Lees, A, Boeve, B F, Petersen, R C, Ferman, T J, Escott-Price, V, Graff-Radford, N, Cairns, N J, Morris, J C, Pickering-Brown, S, Mann, D, Halliday, G, Stone, D J, Dickson, D W, Hardy, J, Singleton, A, Guerreiro, R & Bras, J 2020, ' Analysis of neurodegenerative disease-causing genes in dementia with Lewy bodies ', Acta Neuropathologica Communinications, vol. 8, no. 1, 5, pp. 5 . https://doi.org/10.1186/s40478-020-0879-z
Acta Neuropathologica Communications
Acta Neuropathologica Communinications, 8(1):5. BioMed Central
Dementia with Lewy bodies (DLB) is a clinically heterogeneous disorder with a substantial burden on healthcare. Despite this, the genetic basis of the disorder is not well defined and its boundaries with other neurodegenerative diseases are unclear.
Autor:
Ole A. Andreassen, Vivianna M. Van Deerlin, David Simon, Claire E. Wegel, Guido Alves, Ruwani Wijeyekoon, Jodi Maple-Grødem, Alastair J. Noyce, Roger A. Barker, Bart P.C. van de Warrenburg, Peter Heutink, Shirley Eberly, J. Raphael Gibbs, Alexis Brice, Kumaraswamy Naidu Chitrala, Lasse Pihlstrøm, Marlies van Nimwegen, Khanh-Dung H. Nguyen, Ganqiang Liu, Bernard Ravina, Clemens R. Scherzer, Jean-Christophe Corvol, Bastiaan R. Bloem, Jacobus J. van Hilten, Karol Estrada, Faraz Faghri, Jonathan R. Evans, Daniel Weintraub, Ole-Bjørn Tysnes, Aaron G. Day-Williams, Hampton L. Leonard, Jonggeol J. Kim, Fabrice Danjou, David P. Breen, Samantha J. Hutten, Andrew B. Singleton, Hirotaka Iwaki, Peggy Auinger, Mike A. Nalls, Kirsten M. Scott, Dena G. Hernandez, Mathias Toft, Jacqueline Rick, Caroline H. Williams-Gray, Cornelis Blauwendraat
Publikováno v:
2019, ' Genomewide association study of Parkinson's disease clinical biomarkers in 12 longitudinal patients' cohorts ', Movement Disorders, vol. 34, no. 12 . https://doi.org/10.1002/mds.27845
Movement Disorders, 34, 1839-1850
Movement disorders 34(12), 1839-1850 (2019). doi:10.1002/mds.27845
Mov Disord
Movement Disorders
Movement Disorders, 34, 12, pp. 1839-1850
Movement Disorders, 34, 1839-1850
Movement disorders 34(12), 1839-1850 (2019). doi:10.1002/mds.27845
Mov Disord
Movement Disorders
Movement Disorders, 34, 12, pp. 1839-1850
Item does not contain fulltext BACKGROUND: Several reports have identified different patterns of Parkinson's disease progression in individuals carrying missense variants in GBA or LRRK2 genes. The overall contribution of genetic factors to the sever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d75d743e4735219496720da03a92501
https://www.pure.ed.ac.uk/ws/files/112990604/Breen_GWAS_MovtDisorders.pdf
https://www.pure.ed.ac.uk/ws/files/112990604/Breen_GWAS_MovtDisorders.pdf
Autor:
Oliver H. Tam, Nikolay V. Rozhkov, Regina Shaw, Duyang Kim, Isabel Hubbard, Samantha Fennessey, Nadia Propp, Delphine Fagegaltier, Brent T. Harris, Lyle W. Ostrow, Hemali Phatnani, John Ravits, Josh Dubnau, Molly Gale Hammell, Justin Kwan, Dhruv Sareen, James R. Broach, Zachary Simmons, Ximena Arcila-Londono, Edward B. Lee, Vivianna M. Van Deerlin, Neil A. Shneider, Ernest Fraenkel, Frank Baas, Noah Zaitlen, James D. Berry, Andrea Malaspina, Pietro Fratta, Gregory A. Cox, Leslie M. Thompson, Steve Finkbeiner, Efthimios Dardiotis, Timothy M. Miller, Siddharthan Chandran, Suvankar Pal, Eran Hornstein, Daniel J. MacGowan, Terry Heiman-Patterson, Molly G. Hammell, Nikolaos.A. Patsopoulos, Oleg Butovsky, Joshua Dubnau, Avindra Nath, Robert Bowser, Matt Harms, Eleonora Aronica, Mary Poss, Jennifer Phillips-Cremins, John Crary, Nazem Atassi, Dale J. Lange, Darius J. Adams, Leonidas Stefanis, Marc Gotkine, Robert Baloh, Suma Babu, Towfique Raj, Sabrina Paganoni, Ophir Shalem, Colin Smith, Bin Zhang
Publikováno v:
Cell Reports, 29(5), 1164-1177.e5. Cell Press
Cell Reports, Vol 29, Iss 5, Pp 1164-1177.e5 (2019)
Cell Reports, 29(5), 1164-+. CELL PRESS
2019, ' Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS : Retrotransposon Activation, Oxidative Stress, and Activated Glia ', Cell Reports, vol. 29, no. 5, pp. 1164-1177.e5 . https://doi.org/10.1016/j.celrep.2019.09.066
Tam, O H, Rozhkov, N V, Shaw, R, Kim, D, Hubbard, I, Fennessey, S, Propp, N, Phatnani, H, Ostrow, L W, Harris, B T, Fagegaltier, D, Ravits, J, Dubnau, J, Gale Hammell, M & The NYGC ALS Consortium 2019, ' Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS : Retrotransposon Activation, Oxidative Stress, and Activated Glia ', Cell Reports, vol. 29, no. 5, pp. 1164-1177.e5 . https://doi.org/10.1016/j.celrep.2019.09.066
Cell reports, 29(5), 1164-1177.e5. Cell Press
Cell reports
Cell Reports, Vol 29, Iss 5, Pp 1164-1177.e5 (2019)
Cell Reports, 29(5), 1164-+. CELL PRESS
2019, ' Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS : Retrotransposon Activation, Oxidative Stress, and Activated Glia ', Cell Reports, vol. 29, no. 5, pp. 1164-1177.e5 . https://doi.org/10.1016/j.celrep.2019.09.066
Tam, O H, Rozhkov, N V, Shaw, R, Kim, D, Hubbard, I, Fennessey, S, Propp, N, Phatnani, H, Ostrow, L W, Harris, B T, Fagegaltier, D, Ravits, J, Dubnau, J, Gale Hammell, M & The NYGC ALS Consortium 2019, ' Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS : Retrotransposon Activation, Oxidative Stress, and Activated Glia ', Cell Reports, vol. 29, no. 5, pp. 1164-1177.e5 . https://doi.org/10.1016/j.celrep.2019.09.066
Cell reports, 29(5), 1164-1177.e5. Cell Press
Cell reports
SUMMARY Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the progressive loss of motor neurons. While several pathogenic mutations have been identified, the vast majority of ALS cases have no family history of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0f9b5e94076f435321c49afe1e6a5bb
https://research.vumc.nl/en/publications/a2a8d932-ef9e-4f04-8c5d-978752a1e996
https://research.vumc.nl/en/publications/a2a8d932-ef9e-4f04-8c5d-978752a1e996
Autor:
Nabila Dahodwala, Alice Chen-Plotkin, Sharon X. Xie, Jacqueline Rick, Lana M. Chahine, Leslie M. Shaw, John Q. Trojanowski, Daniel Weintraub, Thomas F. Tropea, Jimit Doshi, Vivianna M. Van Deerlin, Christos Davatzikos
Publikováno v:
Movement Disorders. 33:289-297
BACKGROUND People with PD are at high risk of developing cognitive impairment and dementia. Cross-sectional studies have identified candidate biomarkers associated with cognitive decline. However, longitudinal studies on this topic are rarer, and few
Autor:
Linda K. Kwong, Lior Rennert, Murray Grossman, John Q. Trojanowski, Ahmed Yousef, Matthew D. Byrne, EunRan Suh, Yan Xu, Vivianna M. Van Deerlin, Sharon X. Xie, Virginia M.-Y. Lee, Edward B. Lee, John L. Robinson, David J. Irwin
Publikováno v:
Acta Neuropathologica Communications, Vol 5, Iss 1, Pp 1-15 (2017)
Acta Neuropathologica Communications
Acta Neuropathologica Communications
Frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) is associated with the accumulation of pathological neuronal and glial intracytoplasmic inclusions as well as accompanying neuron loss. We explored if cortical neurons detected by Ne