Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Daire O'Shea"'
Autor:
Deepali Kumar, Anders Åsberg, Luiz F. Lisboa, Atul Humar, Daire O'Shea, Vincent C. Emery, Adrian Egli, Thomas F. Mueller
Publikováno v:
American Journal of Transplantation
Human (Homo sapiens) micro-RNAs (hsa-miRNAs) regulate virus and host-gene translation, but the biological impact in patients with human cytomegalovirus (hCMV) infection is not well defined in a clinically relevant model. First, we compared hsa-miRNA
Autor:
Shahid Husain, Atul Humar, Oriol Manuel, Jared Fairbanks, Daire O'Shea, Deepali Kumar, Luiz F. Lisboa, Adrian Egli
Publikováno v:
American Journal of Transplantation. 15:1882-1892
Monitoring of cytomegalovirus cell-mediated immunity is a promising tool for the refinement of preventative and therapeutic strategies posttransplantation. Typically, the interferon-γ response to T cell stimulation is measured. We evaluated a broad
Autor:
Xiao-Li Pang, Anders Åsberg, Daire O'Shea, Halvor Rollag, Atul Humar, D. L. Tyrrell, Luiz F. Lisboa, Deepali Kumar, Anders Hartmann, Adrian Egli
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 15(7)
Cytomegalovirus (CMV) encodes multiple microRNAs. While these have been partially characterized in vitro, their relevance to clinical CMV infection has not been evaluated. We analyzed samples from a cohort of solid organ transplant patients with CMV
Autor:
Daire O'Shea, G. Farrell, Clair M. Gardiner, Markus Peck-Radosavljevic, Thomas Reiberger, Colm Bergin, C Keane
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66831 (2013)
PLoS ONE
PLoS ONE
Pegylated-IFN and ribavirin remains the current treatment for chronic HCV infection in patients co-infected with HIV-1, but this regimen has low efficacy rates, particularly for HCV genotype 1/4 infection, has severe side effects and is extremely cos
Autor:
Leticia E. Wilson, Luiz Augusto Ferreira Lisboa, Adrian Egli, Luis G. Hidalgo, Moacyr Silva, Daire O'Shea, Deepali Kumar, Aliyah Baluch, Atul Humar
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 11, p e43937 (2012)
PLoS ONE, Vol 7, Iss 11, p e43937 (2012)
BACKGROUND: CMV-specific T-cells are crucial to control CMV-replication post-transplant. Regulatory T-cells (T-regs) are associated with a tolerant immune state and may contribute to CMV-replication. However, T-cell subsets such as T-regs and IL-17 p