Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Angelica M. Gutierrez Barrera"'
Outcomes After Breast Radiation Therapy in a Diverse Patient Cohort With a Germline BRCA1/2 Mutation
Autor:
Jennifer K. Litton, Isabelle Bedrosian, Bhavana V. Chapman, Shane R. Stecklein, Michael C. Stauder, Yu Shen, Eric A. Strom, David S. Lakomy, George H. Perkins, Karen E. Hoffman, Scott J. Bright, Simona F. Shaitelman, Wendy A. Woodward, Angelica M. Gutierrez Barrera, Gabriel O. Sawakuchi, Banu Arun, Oluwafikayo O. Olamigoke, Diane Liu, Benjamin Smith
Publikováno v:
Int J Radiat Oncol Biol Phys
Purpose BRCA1/2 pathogenic variant (PV) mutations confer radiation sensitivity preclinically, but there are limited data regarding breast cancer outcomes after radiation therapy (RT) among patients with documented BRCA1/2 PV mutations versus no PV mu
Publikováno v:
The Breast Journal. 26:1337-1342
Currently, the NCCN guidelines recommend testing of BRCA1 and BRCA2 for females with multiple breast primaries, if her first diagnosis was ≤50 years old. With the increase in uptake of multigene panels, testing for genes outside of BRCA1 and BRCA2
Autor:
Michael C. Stauder, Diane Liu, George H. Perkins, David S. Lakomy, Scott J. Bright, Isabelle Bedrosian, Jennifer K. Litton, Shane R. Stecklein, Banu Arun, Karen E. Hoffman, Angelica M. Gutierrez Barrera, Eric A. Strom, Benjamin Smith, Wendy A. Woodward, Bhavana V. Chapman, Oluwafikayo O. Olamigoke, Yu Shen, Simona F. Shaitelman, Gabriel O. Sawakuchi
Publikováno v:
Int J Radiat Oncol Biol Phys
Purpose Multigene panel testing has increased the detection of germline mutations in patients with breast cancer. The implications of using radiation therapy (RT) to treat patients with pathogenic variant (PV) mutations are not well understood and ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebe8ea24ab59230298e102764e38bc42
https://europepmc.org/articles/PMC8748284/
https://europepmc.org/articles/PMC8748284/
Autor:
Loredana Militello, Constance Albarracin, Banu Arun, Isabelle Bedrosian, Angelica M. Gutierrez Barrera
Publikováno v:
Cancer Research. 80:P6-08
Background: Pathogenic ATM gene mutations are associated with increased risk of developing several cancers such as lymphoid, gastric, breast, central nervous system, skin, and other cancers. The relative risk of breast cancer is 2.3, with a higher ri
Autor:
Nuhad K. Ibrahim, Angelica M. Gutierrez-Barrera, Michael J. Lehner, Jennifer K. Litton, Akshara Singareeka Raghavendra, Haven R. Garber, Banu Arun, Debu Tripathy
Publikováno v:
Journal of Clinical Oncology. 38:1096-1096
1096 Background: Previous reports suggest the incidence of brain metastasis is higher in patients with hereditary BRCA1 mutations compared to BRCA1 noncarriers among breast cancer patients who develop recurrent disease. PARP inhibitors are now standa
Autor:
Ashley H. Woodson, Michelle Jackson, Angelica M. Gutierrez-Barrera, Banu Arun, Kimberly I. Muse, Jennifer K. Litton, Henry Mark Kuerer, George Baum, Nisreen Elsayegh, P Jessica
Publikováno v:
Cancer Research. 73:P5-13
Background: The rate of prophylactic mastectomy (PM) has recently increased1. A deleterious mutation in the BRCA1 or BRCA 2 genes is among the major reasons why patients pursue PM 2, 3. Women with BRCA1 or BRCA2 gene mutations have up to an 87% risk
Autor:
N. Tankhiwale, Gabriel N. Hortobagyi, Swati Biswas, Banu Arun, Jennifer K. Litton, Angelica M. Gutierrez-Barrera, Giovanni Parmigiani, Christopher I. Amos, Amanda L. Blackford
Publikováno v:
Journal of Clinical Oncology. 29:164-164
164 Background: BRCAPRO is a widely used genetic risk prediction model for estimating the carrier probabilities of mutations in BRCA1/2 genes. BRCAPRO has been enhanced to utilize information on molecular markers ER, PR, CK5/6, and CK14. However, no