Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Salman, R"'
Autor:
Davidson MD; School of Biomedical Engineering, Colorado State University, Fort Collins, CO, United States; Department of Bioengineering, University of Illinois at Chicago, Chicago, IL, United States., Pickrell J; School of Biomedical Engineering, Colorado State University, Fort Collins, CO, United States; Department of Mechanical Engineering, Colorado State University, Fort Collins, CO, United States., Khetani SR; School of Biomedical Engineering, Colorado State University, Fort Collins, CO, United States; Department of Mechanical Engineering, Colorado State University, Fort Collins, CO, United States; Department of Bioengineering, University of Illinois at Chicago, Chicago, IL, United States. Electronic address: skhetani@uic.edu.
Publikováno v:
Toxicology [Toxicology] 2021 Feb 15; Vol. 449, pp. 152662. Date of Electronic Publication: 2020 Dec 24.
Autor:
Kukla DA; Department of Bioengineering, University of Illinois at ChicagoChicago, ILUSA., Crampton AL; Department of Biomedical Engineering, University of MinnesotaMinneapolis, MNUSA., Wood DK; Department of Biomedical Engineering, University of MinnesotaMinneapolis, MNUSA., Khetani SR; Department of Bioengineering, University of Illinois at ChicagoChicago, ILUSA.
Publikováno v:
Gene expression [Gene Expr] 2020 Jun 12; Vol. 20 (1), pp. 1-18. Date of Electronic Publication: 2020 Apr 14.
Autor:
Lin C; School of Biomedical Engineering, Colorado State University, Fort Collins, Colorado.; Department of Bioengineering, University of Illinois at Chicago, Chicago, Illinois., Khetani SR; Department of Bioengineering, University of Illinois at Chicago, Chicago, Illinois.
Publikováno v:
Current protocols in toxicology [Curr Protoc Toxicol] 2017 May 02; Vol. 72, pp. 14.17.1-14.17.23. Date of Electronic Publication: 2017 May 02.
Autor:
March S; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Department of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA., Ramanan V; Department of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA., Trehan K; Department of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA., Ng S; Department of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA., Galstian A; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Department of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA., Gural N; Department of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA., Scull MA; Laboratory of Virology and Infectious Disease, Center for the Study of Hepatitis C, The Rockefeller University, New York, New York, USA., Shlomai A; Laboratory of Virology and Infectious Disease, Center for the Study of Hepatitis C, The Rockefeller University, New York, New York, USA., Mota MM; Unidade de Malaria, Instituto de Medicina Molecular, Universidade de Lisboa, Lisboa, Portugal., Fleming HE; Department of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA., Khetani SR; Department of Mechanical Engineering, School of Biomedical Engineering, Colorado State University, Fort Collins, Colorado, USA., Rice CM; Laboratory of Virology and Infectious Disease, Center for the Study of Hepatitis C, The Rockefeller University, New York, New York, USA., Bhatia SN; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Department of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.; Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.; Howard Hughes Medical Institute, Cambridge, Massachusetts, USA.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
Publikováno v:
Nature protocols [Nat Protoc] 2015 Dec; Vol. 10 (12), pp. 2027-53. Date of Electronic Publication: 2015 Nov 19.
Autor:
Ukairo O; Hepregen Corporation, Suite 1500, Medford, MA 2155, USA., Kanchagar C, Moore A, Shi J, Gaffney J, Aoyama S, Rose K, Krzyzewski S, McGeehan J, Andersen ME, Khetani SR, Lecluyse EL
Publikováno v:
Journal of biochemical and molecular toxicology [J Biochem Mol Toxicol] 2013 Mar; Vol. 27 (3), pp. 204-12. Date of Electronic Publication: 2013 Jan 11.
Autor:
Wang WW; Pfizer Global Research and Development, Eastern Point Rd., Groton, CT 06340, USA., Khetani SR, Krzyzewski S, Duignan DB, Obach RS
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2010 Oct; Vol. 38 (10), pp. 1900-5. Date of Electronic Publication: 2010 Jul 01.
Publikováno v:
Gene Expr
Human liver models that are three-dimensional (3D) in architecture are indispensable for compound metabolism/toxicity screening, to model liver diseases for drug discovery, and for cell-based therapies; however, further development of such models is
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 181(1)
Human liver models are useful for assessing compound metabolism/toxicity; however, primary human hepatocyte (PHH) lots are limited and highly variable in quality/viability. In contrast, cell lines, such as HepaRG, are cheaper and more reproducible su
Publikováno v:
Drug Metabolism and Disposition. 46:1626-1637
Metabolism in the liver often determines the overall clearance rates of many pharmaceuticals. Furthermore, induction or inhibition of the liver drug metabolism enzymes by perpetrator drugs can influence the metabolism of victim drugs (drug-drug inter
Autor:
Salman R. Khetani, Matthew D. Davidson
Publikováno v:
Toxicol Sci
Primary human hepatocyte (PHH) cultures have become indispensable to mitigate the risk of adverse drug reactions in human patients. In contrast to de-differentiating monocultures, co-culture with non-parenchymal cells maintains PHH functions for 2-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b98e428457358d89a3b6d8101ff9b7c2