Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ena Wang"'
Autor:
Willem W. Overwijk, Patrick Hwu, Francesco M. Marincola, Geok Choo Sim, Caitlin Creasy, Laszlo Radvanyi, Chengwen Liu, Elizabeth A. Grimm, Hui Liu, Zhimin Dai, Ena Wang, Jason Roszik
Publikováno v:
Cancer Immunology Research. 4:983-994
Clinical responses to high-dose IL2 therapy are limited due to selective expansion of CD4+CD25+Foxp3+ T-regulatory cells (Treg), especially ICOS+ Tregs, rather than natural killer (NK) cells and effector T cells. These ICOS+ Tregs are highly suppress
Autor:
Daniel J. Powell, Lana E. Kandalaft, Renee Frank, Thomas Garrabrant, Priyanka Duttagupta, Hongzhe Li, Denarda Dangaj, Davide Bedognetti, Ian S. Hagemann, George Coukos, Emese Zsiros, Ena Wang, Michael Feldman, Janos L. Tanyi, Francesco M. Marincola, Carl H. June, Lin Zhang, Bruce L. Levine
Publikováno v:
Clinical Cancer Research, vol. 21, no. 12, pp. 2840-2850
Purpose: Chemokines are implicated in T-cell trafficking. We mapped the chemokine landscape in advanced stage ovarian cancer and characterized the expression of cognate receptors in autologous dendritic cell (DC)–vaccine primed T cells in the conte
Autor:
Michael A. Black, Sandra Demaria, Ashok K. Pullikuth, Angela Tatiana Alistar, Ena Wang, Julia Chifman, Jeff A Chou, Francesco M. Marincola, Cristin G. Print, Eran R. Andrechek, Xiaobo Zhou, Thomas C. Putti, Wouter Hendrickx, Davide Bedognetti, Lance D. Miller, Jonathan P. Rennhack
The abundance and functional orientation of tumor-infiltrating lymphocytes in breast cancer is associated with distant metastasis-free survival, yet how this association is influenced by tumor phenotypic heterogeneity is poorly understood. Here, a bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfa1784e8eed1d0e64aa28a674919819
https://europepmc.org/articles/PMC4930674/
https://europepmc.org/articles/PMC4930674/
Autor:
Robert B. Nussenblatt, Ena Wang, Huizhi Zhou, Foo Cheung, John S. Tsang, Rongye Shi, Yuri Kotliarov, Matthew J. Olnes, Jinguo Chen, Angelique Biancotto
Publikováno v:
Scientific Reports
Corticosteroids have been used for decades to modulate inflammation therapeutically, yet there is a paucity of data on their effects in humans. We examined the changes in cellular and molecular immune system parameters, or “immunome”, in healthy
Autor:
Luigi Buonaguro, Francesco M. Marincola, Maria Lina Tornesello, Francesco Izzo, Andrea Worschech, Ena Wang, Franco M. Buonaguro, Valeria De Giorgi
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56153 (2013)
PLoS ONE
PLoS ONE
Hepatocellular carcinomas (HCCs) are a heterogeneous group of tumors that differ in risk factors and genetic alterations. In Italy, particularly Southern Italy, chronic hepatitis C virus (HCV) infection represents the main cause of HCC. Using high-de
Autor:
Andrea Worschech, Yingdong Zhao, Aladar A. Szalay, Maria Libera Ascierto, Richard J. Aguilar, Qian Zhang, Nanhai G. Chen, Jennifer Reinboth, Ena Wang, Yong A. Yu, Rafael Carretero, Francesco M. Marincola
Publikováno v:
Human gene therapy methods. 23(5)
Vaccinia virus (VACV) has emerged as an attractive tool in oncolytic virotherapy. VACV replication efficiency plays a crucial role in the therapeutic outcome. However, little is known about the influence of host factors on viral replication efficienc
Autor:
David F. Stroncek, Giovanni Di Pasquale, Sharon Adams, Rahul Roychoudhuri, Jennifer Reinboth, Lorenzo Uccellini, Andrea Worschech, Francesco M. Marincola, Paolo A. Ascierto, Zhiya Yu, Maria Libera Ascierto, Ena Wang, Nicholas P. Restifo, Fabio Rossano, Davide Bedognetti, Aladar A. Szalay, Nanhai G. Chen, Zoltan Pos
Publikováno v:
BMC Cancer, Vol 11, Iss 1, p 451 (2011)
BMC Cancer
BMC Cancer
Background Oncolytic viral therapy represents an alternative therapeutic strategy for the treatment of cancer. We previously described GLV-1h68, a modified Vaccinia Virus with exclusive tropism for tumor cells, and we observed a cell line-specific re
Autor:
Xiang-Yang Wang, Harry D. Bear, Viswanathan Ramakrishnan, Ena Wang, Michael O. Idowu, Margaret M. Grimes, Masoud H. Manjili, Maria Libera Ascierto, Rose H. Manjili, Yingdong Zhao, Francesco M. Marincola, Catherine I. Dumur, Maciej Kmieciak
Publikováno v:
Breast cancer research and treatment. 131(3)
The clinical significance of tumor-infiltrating immune cells has been reported in a variety of human carcinomas including breast cancer. However, molecular signature of tumor-infiltrating immune cells and their prognostic value in breast cancer patie
Autor:
Francesco M. Marincola, Luigi Buonaguro, Alessandro Monaco, Andrea Worchech, Franco M. Buonaguro, Ena Wang, Francesco Izzo, Marialina Tornesello, Valeria De Giorgi
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, Vol 7, Iss 1, p 85 (2009)
Journal of Translational Medicine, Vol 7, Iss 1, p 85 (2009)
Background Hepatitis C virus (HCV) infection is a major cause of hepatocellular carcinoma (HCC) worldwide. The molecular mechanisms of HCV-induced hepatocarcinogenesis are not yet fully elucidated. Besides indirect effects as tissue inflammation and
Publikováno v:
Journal of Translational Medicine, Vol 7, Iss 1, p 20 (2009)
Journal of Translational Medicine
Journal of Translational Medicine
Background The unique features of human embryonic stem (hES) cells make them the best candidate resource for both cell replacement therapy and development research. However, the molecular mechanisms responsible for the simultaneous maintenance of the