Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Stephen H. Bryant"'
Autor:
Thomas Madej, Manoj Tyagi, Benjamin A. Shoemaker, Aron Marchler-Bauer, Dachuan Zhang, Stephen H. Bryant, Ratna R. Thangudu, Anna R. Panchenko, Jessica H. Fong
Publikováno v:
Nucleic Acids Research
IBIS is the NCBI Inferred Biomolecular Interaction Server. This server organizes, analyzes and predicts interaction partners and locations of binding sites in proteins. IBIS provides annotations for different types of binding partners (protein, chemi
Publikováno v:
Bioinformatics
This work provides an analysis of across-target bioactivity results in the screening data deposited in PubChem. Two alternative approaches for grouping-related targets are used to examine a compound's across-target bioactivity. This analysis identifi
Publikováno v:
Journal of Cheminformatics
Background Developing structure–activity relationships (SARs) of molecules is an important approach in facilitating hit exploration in the early stage of drug discovery. Although information on millions of compounds and their bioactivities is freel
Autor:
Dachuan Zhang, Manoj Tyagi, Anna R. Panchenko, Thomas Madej, Stephen H. Bryant, Ratna R. Thangudu
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e28896 (2012)
PLoS ONE
PLoS ONE
The coverage and reliability of protein-protein interactions determined by high-throughput experiments still needs to be improved, especially for higher organisms, therefore the question persists, how interactions can be verified and predicted by com
Autor:
Stephen H. Bryant, Manoj Tyagi, Benjamin A. Shoemaker, Ratna R. Thangudu, Thomas Madej, Anna R. Panchenko
Publikováno v:
BMC Bioinformatics, Vol 11, Iss 1, p 365 (2010)
BMC Bioinformatics
BMC Bioinformatics
Background The study of protein-small molecule interactions is vital for understanding protein function and for practical applications in drug discovery. To benefit from the rapidly increasing structural data, it is essential to improve the tools tha