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of 3
pro vyhledávání: '"Stanford J, Stewart"'
Autor:
Dennis J. Slamon, Mansoor N. Saleh, Stanford J. Stewart, Joanne E. Mortimer, Andrew Arnold, Debasish Tripathy, Melody A. Cobleigh, M. Murphy
Publikováno v:
Journal of Clinical Oncology. 22:1063-1070
Purpose In a pivotal phase III trial, the addition of trastuzumab to chemotherapy significantly improved response rate, time to disease progression, and overall survival in women with HER2 overexpressing metastatic breast cancer. We conducted an exte
Autor:
Stanford J. Stewart, Michael Burchmore, Steven Shak, M. Murphy, William Novotny, Dennis J. Slamon, Louis Fehrenbacher, John Gutheil, Lyndsay Harris, Debasish Tripathy, Melody A. Cobleigh, Charles L. Vogel
Publikováno v:
European Journal of Cancer. 37:25-29
Following confirmation of the appropriate dosage, safety and potential efficacy of Herceptin(trastuzumab) in small-scale phase I and II trials involving patients with refractory disease, a large trial was conducted in 222 patients with breast cancer
Autor:
Deborah L. Keefe, Clifford A. Hudis, Stanford J. Stewart, Andrew D. Seidman, Maureen E. Murphy, Mark Ashby, Mary Kathryn Pierri, Virginia E. Paton, Steven Shak
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 20(5)
PURPOSE: This study sought to estimate cardiac dysfunction (CD) risk for patients receiving trastuzumab; to characterize observed CD by severity, treatment, and clinical outcome; to assess effects of baseline clinical risk factors on CD; and to asses