Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Natalia Baran"'
Autor:
Floriant Bellvert, Camille Montersino, Pierre-Luc Mouchel, Brandon Nicolay, Guillaume Cazals, Laurent Fernando, Nicolas Broin, Jean-Charles Portais, Joe Marszalek, Clément Larrue, Norbert Vey, Sebastien Ronseaux, Thomas Farge, Jean-Emmanuel Sarry, Andrei Turtoi, Aliki Zavoriti, Tony Kaoma, Courtney D. DiNardo, Emeline Chu-Van, Claudie Bosc, Guillaume Cognet, Rémy Castellano, Héléna Boutzen, Cédric Cassan, Claire Calmettes, Florence Castelli, Marie Sabatier, Arnaud Pigneux, Evgenia Turtoi, Yves Collette, Martin Carroll, Yves Gibon, Emeline Boet, Laetitia K. Linares, Mathilde Gotanègre, Francois Fenaille, Laurent Le Cam, Lara Gales, Marc Conti, Nathalie Poupin, Mary A. Selak, Lucille Stuani, Andrew Futreal, Christian Recher, Marina Konopleva, Feng Wang, Estelle Saland, Mohsen Hosseini, Audrey Bidet, Kiyomi Morita, Natalia Baran, Koichi Takahashi, Sylvain Loric, Pierre Bories, Fabien Jourdan
Isocitrate dehydrogenases (IDH) are involved in redox control and central metabolism. Mutations in IDH induce epigenetic and transcriptional reprogramming, differentiation bias, BCL-2 dependence and susceptibility to mitochondrial inhibitors in cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55157cd88bc325916e6636c39f8f7b18
https://hal.archives-ouvertes.fr/hal-02935177
https://hal.archives-ouvertes.fr/hal-02935177
Autor:
David Piwnica-Worms, Marina Konopleva, Sriram S. Shanmugavelandy, Pratip K. Bhattacharya, Natalia Baran, Christopher G. Wood, Tianyu Cai, Steven W. Millward, Niki M. Zacharias, Juliana Velez Lujan, Jaehyuk Lee, Prasanta Dutta
Publikováno v:
Molecular cancer therapeutics. 18(11)
Acute myeloid leukemia (AML) is an aggressive hematopoietic disease characterized by glutamine-dependent metabolism. A novel glutaminase (GLS) inhibitor, CB-839, is currently under evaluation for treatment of hematopoietic malignancies and solid tumo
Autor:
Héléna Boutzen, Clément Larrue, Pierre Millard, Laurent Fernando, Laurent Le Cam, Laurie Gayte, Noémie Gadaud, Tony Kaoma, Pierre-Luc Mouchel, Evgenia Turtoi, Jean-Charles Portais, Nesrine Aroua, Justine Bertrand-Michel, Courtney Dinardo, Tony Lionel Palama, Yves Collette, Camille Montersino, Laure Tonini, Yves Gibon, Madi Y. Cissé, Cédric Cassan, Koichi Takahashi, Florence Castelli, Pierre Bories, Audrey Bidet, Joe Marszalek, Martin Carroll, Guillaume Cazals, Claire Calmettes, Arnaud Pigneux, Thomas Farge, Lucille Stuani, Feng Wang, Fabien Jourdan, Laetitia K. Linares, Mary A. Selak, Lara Gales, Andrew M. Futreal, Mathilde Gotanègre, Maud Heuillet, Kiyomi Morita, Jean-Emmanuel Sarry, Andrei Turtoi, Nicolas Broin, Christian Recher, Marina Konopleva, Mohsen Hosseini, Christophe Junot, Claudie Bosc, Emeline Chu-Van, Marine Fraisse, Nathalie Saint-Laurent, Lindsay Peyriga, Rémy Castellano, Estelle Saland, Natalia Baran, Norbert Vey, Frédéric Lopez, Floriant Bellvert, Marie Sabatier, Nathalie Poupin
Publikováno v:
SSRN Electronic Journal.
Isocitrate dehydrogenases (IDH) are involved in redox control and central metabolism. We hypothesized that key metabolic fluxes are selectively reprogrammed to maintain biosynthetic homeostasis and lower drug responses in IDH mutant acute myeloid leu
Autor:
Natalia Baran, Alessia Lodi, Shannon Sweeney, Vinitha Mary Kuruvilla, Antonio Cavazos, Anna Skwarska, Sriram Shanmuga Velandy, Karine Harutyunyan, Ningping Feng, Jason Gay, Marcin Kaminski, Elias J. Jabbour, Adolfo Ferrando, M. Emilia Di Francesco, Joseph R. Marszalek, Stefano Tiziani, Marina Konopleva
Publikováno v:
Cancer Research. 78:1875-1875
Adult T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematologic malignancy with limited treatment options, largely driven by the activating Notch1 mutations. Oncogenic Notch1 facilitates c-Myc signaling and glutamine oxidation, induces
Autor:
Natalia Baran, Jennifer Molina, Antonio Cavazos, Karine Harutyunyan, Ningping Feng, Jason Gay, Sujan Piya, Sriram Shanmuga Velandy, Elias J. Jabbour, Michael Andreeff, Stefano Tiziani, Adolfo A. Ferrando, Patrick Zweidler-McKay, M. Emilia Di Francesco, Joseph R. Marszalek, Marina Konopleva
Publikováno v:
Blood. 128:4028-4028
Metabolic reprogramming of the key energy-generating pathways has been long recognized as one of the key oncogenic properties of cancer including leukemia. While accelerated glycolysis is considered to be most common feature of tumors, reliance on ox