Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Qianfen Liu"'
NTNG1 Modulates Cisplatin Resistance in Epithelial Ovarian Cancer Cells via the GAS6/AXL/Akt Pathway
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Cisplatin resistance is a challenge in the treatment of epithelial ovarian cancer. Here, clinical data showed that the level of netrin-G1 (NTNG1) in cisplatin-resistant cancer was higher than that in cisplatin-sensitive cancer (2.2-fold, p = 0.005);
Externí odkaz:
https://doaj.org/article/1b83156ce46a47649e4ae65abef04653
Publikováno v:
Molecular pharmaceutics. 17(6)
Prodrug-carboxypeptidase G2 (e.g., ZD2767P+CPG2) can realize a targeted treatment where the specific advantage is a lack of CPG2 analogues in humans, but it is limited by low efficacy. Here ultrasound was employed to enhance ZD2767P+CPG2 (i.e., ZD276