Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Matthew R. Sarkisian"'
Autor:
Jia Tian, Lan Hoang-Minh, Reemsha Basrai, Joseph J. Lebowitz, Matthew R. Sarkisian, Alice Cheng, Habibeh Khoshbouei, Loic P. Deleyrolle, Neil Kalaria, Ping Shi
Publikováno v:
Cancers, Vol 13, Iss 1644, p 1644 (2021)
Cancers
Volume 13
Issue 7
Cancers
Volume 13
Issue 7
Simple Summary Glioblastoma is the most common and lethal brain tumor in adults because it becomes resistant to virtually every treatment. Histone deacetylase 6 (HDAC6), which is located primarily in the cytoplasm, has a unique role in promoting the
Autor:
Matthew R. Sarkisian, Megan M. Le, George Ugartemendia, Lan Hoang-Minh, Tyler S. Smith, Alexander K. Parker, Jason E. Coleman, Eric W. Atkinson, Susan L. Semple-Rowland
Publikováno v:
Experimental Neurology. 282:119-127
Neonatal or early-life seizures (ELS) are often associated with life-long neurophysiological, cognitive and behavioral deficits, but the underlying mechanisms contributing to these deficits remain poorly understood. Newborn, post-migratory cortical n
Autor:
Gabriel De Leon, Matthew R. Sarkisian, George Ugartemendia, Benjamin Griffith, Susan L. Semple-Rowland, Brent A. Reynolds, Loic P. Deleyrolle, Duane Mitchell, Hunter S. Futch, Dorit Siebzehnrubl, Lan Hoang-Minh, Joshua J. Breunig
Publikováno v:
Oncotarget, vol 7, iss 6
Oncotarget
Oncotarget
// Lan B. Hoang-Minh 1, 3 , Loic P. Deleyrolle 2, 3 , Dorit Siebzehnrubl 1 , George Ugartemendia 1 , Hunter Futch 2 , Benjamin Griffith 2 , Joshua J. Breunig 5- 9 , Gabriel De Leon 2, 4 , Duane A. Mitchell 2, 3, 4 , Susan Semple-Rowland 1 , Brent A.
Autor:
Matthew R. Sarkisian, Loic P. Deleyrolle, Brent A. Reynolds, Regina T. Martuscello, Nariaki S. Nakamura, Alexander K. Parker, Lan Hoang-Minh
Publikováno v:
Translational Oncology
Translational Oncology, Vol 9, Iss 5, Pp 392-402 (2016)
Translational Oncology, Vol 9, Iss 5, Pp 392-402 (2016)
A better understanding of the molecules implicated in the growth and survival of glioblastoma (GBM) cells and their response to temozolomide (TMZ), the standard-of-care chemotherapeutic agent, is necessary for the development of new therapies that wo
Autor:
Xiuxin Liu, Richard A. Flavell, Matthew R. Sarkisian, Albert E. Ayoub, A. Rachel Gallagher, Anthony F. Ferrandino, Charalampos G. Spilianakis, Ming O. Li, Joshua J. Breunig, Pasko Rakic, Terrence Town
Publikováno v:
Proceedings of the National Academy of Sciences. 105:2853-2858
Cilia are present on nearly all cell types in mammals and perform remarkably diverse functions. However, the mechanisms underlying ciliogenesis are unclear. Here, we cloned a previously uncharacterized highly conserved gene, stumpy , located on mouse
Autor:
Matthew R. Sarkisian, Brent A. Reynolds, Lan Hoang-Minh, Loic P. Deleyrolle, Nariaki S. Nakamura
Publikováno v:
Neuro-Oncology. 18:vi40-vi40
Autor:
Joshua J. Breunig, Sarah M. Guadiana, Kirk Mykytyn, Matthew R. Sarkisian, Irina Madorsky, Daniel Daroszewski, Susan L. Semple-Rowland
The formation of primary cilia is a highly choreographed process that can be disrupted in developing neurons by overexpressing neuromodulatory G-protein-coupled receptors GPCRs or by blocking intraflagellar transport. Here, we examined the effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb73c6bc365e2d4d82c745424b8be141
https://europepmc.org/articles/PMC6619186/
https://europepmc.org/articles/PMC6619186/
Publikováno v:
Cilia and Nervous System Development and Function ISBN: 9789400758070
The prevailing view until very recently was that primary neuronal cilia, which were first described in electron microscopic studies of the central nervous system (CNS) approximately 50 years ago, were likely vestigial. This was due in large part to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80999f9dc464534e21707f670f6de537
https://doi.org/10.1007/978-94-007-5808-7_4
https://doi.org/10.1007/978-94-007-5808-7_4
Publikováno v:
The Journal of comparative neurology. 520(4)
Neuronal primary cilia are not generally recognized, but they are considered to extend from most, if not all, neurons in the neocortex. However, when and how cilia develop in neurons are not known. This study used immunohistochemistry for adenylyl cy
Autor:
Sara B. Anastas, Dorit Mueller, Joshua J. Breunig, Matthew R. Sarkisian, Susan L. Semple-Rowland
Publikováno v:
Cerebral cortex (New York, N.Y. : 1991). 21(2)
Most, if not all, cortical neurons possess a single primary cilium; however, little is known about the mechanisms that control neuronal ciliogenesis. The Citron kinase-deficient (Citron-K(fh/fh)) rat, a model in which failed cytokinesis during develo