Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Pedro R. Lowenstein"'
Autor:
Stephen Carney, Andrea Comba, Maria B. Garcia-Fabiani, Alejandro Javier Nicola Candia, Ava Mauser, Anna Schwendeman, Maria Ventosa, Marianela Candolfi, Lindsay Scheetz, Pedro R. Lowenstein, Mahmoud S. Alghamri, Padma Kadiyala, James J. Moon, Joerg Lahann, Maria G. Castro, Syed M Faisal
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Gliomas are infiltrating brain tumors associated with high morbidity and mortality. Current standard of care includes radiation, chemotherapy and surgical resection. Today, survival rates for malignant glioma patients remain dismal and unchanged for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb1626dafe0a01d701a6f662b67b397
https://www.tandfonline.com/doi/full/10.1080/13543784.2020.1768528
https://www.tandfonline.com/doi/full/10.1080/13543784.2020.1768528
Autor:
Marianela Candolfi, Mahmoud S. Alghamri, David B. Altshuler, Maria G. Castro, Felipe J Nunez, Padma Kadiyala, Antonela Sofía Asad, Stephen Carney, Anna Schwendeman, Joerg Lahann, Alejandro Javier Nicola Candia, Fernando M. Nunez, Pedro R. Lowenstein, James J. Moon, Maria B. Garcia-Fabiani
Publikováno v:
Expert Opin Biol Ther
Introduction: The field of neuro-oncology has experienced significant advances in recent years. More is known now about the molecular and genetic characteristics of glioma than ever before. This knowledge leads to the understanding of glioma biology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84060f4e081cdde6482b43f3709cfb06
https://europepmc.org/articles/PMC7059118/
https://europepmc.org/articles/PMC7059118/
Autor:
Meghna Saxena, Pedro R. Lowenstein, Youping Li, Maria G. Castro, Neha Kamran, Nicholas Raja, Padma Kadiyala, Diana Shah, Mariela A. Moreno-Ayala, Marianela Candolfi
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Survival of glioma (GBM) patients treated with the current standard of care remains dismal. Immunotherapeutic approaches that harness the cytotoxic and memory potential of the host immune system have shown great benefit in other cancers. GBMs have de
Autor:
Pedro R. Lowenstein, Diana Shah, Carl Koschmann, Mayuri Chandran, Antonela Sofía Asad, Maria G. Castro, Yohei Mineharu, Viveka Nand Yadav, Marianela Candolfi
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Introduction: Malignant gliomas are highly invasive tumors, associated with a dismal survival rate despite standard of care, which includes surgical resection, radiotherapy and chemotherapy with temozolomide (TMZ). Precision immunotherapies or combin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f12dd2baa5a047ee9c7156f7bfac1e7
https://www.tandfonline.com/doi/full/10.1080/14712598.2017.1305353
https://www.tandfonline.com/doi/full/10.1080/14712598.2017.1305353
Autor:
Maria G. Castro, Felipe J Nunez, Yohei Mineharu, Carl Koschmann, Antonela Sofía Asad, Mayuri Chandran, Marianela Candolfi, Neha Kamran, Pedro R. Lowenstein, Alexandra Calinescu
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Introduction: Outcome for glioma (GBM) remains dismal despite advances in therapeutic interventions including chemotherapy, radiotherapy and surgical resection. The overall survival benefit observed with immunotherapies in cancers such as melanoma an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14396b642924bc4091cae6037147df5b
https://www.tandfonline.com/doi/full/10.1080/14712598.2016.1212012
https://www.tandfonline.com/doi/full/10.1080/14712598.2016.1212012
Autor:
Mariela A. Moreno Ayala, Marianela Candolfi, Neha Kamran, Pedro R. Lowenstein, Marta Dzaman, Gregory J. Baker, Maria G. Castro
Publikováno v:
Gene Therapy for Neurological Disorders : Methods and Protocols
Gene Therapy for Neurological Disorders ISBN: 9781493932702
Gene Therapy for Neurological Disorders ISBN: 9781493932702
Glioblastoma multiforme (GBM) is the most common primary brain tumor in adults with a median survival of 16.2–21.2 months post diagnosis (Stupp et al., N Engl J Med 352(10): 987–996, 2005). Because of its location, complete surgical resection is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78ffa175e24e22a70f812f6a4ad09734
https://link.springer.com/protocol/10.1007/978-1-4939-3271-9_31
https://link.springer.com/protocol/10.1007/978-1-4939-3271-9_31
Autor:
Maria G. Castro, Yohei Mineharu, Kader Yagiz, Pedro R. Lowenstein, Akm Ghulam Muhammad, Kurt M. Kroeger, Nick Barnett, Régis Josien, Gwendalyn D. King, Marianela Candolfi, David Foulad, James F. Curtin
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 8, Pp 757-770 (2012)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Adenovirus-mediated delivery of the immune-stimulatory cytokine Flt3L and the conditionally cytotoxic thymidine kinase (TK) induces tumor regression and long-term survival in preclinical glioma (glioblastoma multiforme [GBM]) models. Flt3L induces ex
Autor:
Marianela Candolfi, Hikmat Assi, Mariela A. Moreno-Ayala, Alexandra Calinescu, Carl Koschmann, Neha Kamran, Christopher Paran, Pedro R. Lowenstein, Thomas J. Wilson, Maria G. Castro
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
INTRODUCTION: Glioblastoma multiforme (GBM) is the most common primary brain tumor in adults and it carries a dismal prognosis. Adenoviral vector (Ad)-mediated gene transfer is being developed as a promising therapeutic strategy for GBM. Preclinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e617accb928337da1cdc7c4e98063a93
http://www.tandfonline.com/doi/full/10.1517/14712598.2014.915307
http://www.tandfonline.com/doi/full/10.1517/14712598.2014.915307
Autor:
Pedro R. Lowenstein, Maria G. Castro, Homayon Ghiasi, Mia Wibowo, Marianela Candolfi, Neha Kamran, Gabrielle E. Ahlzadeh, Mariana Puntel, Christopher Paran, Kader Yagiz
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PURPOSE: Glioblastoma multiforme is the most common primary brain cancer in adults. Chemotherapy with temozolomide (TMZ) significantly prolongs the survival of patients with glioblastoma multiforme. However, the three-year survival is still approxima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::574354a687ad1e9fc464a5f4dc4a5375
http://clincancerres.aacrjournals.org/content/20/6/1555
http://clincancerres.aacrjournals.org/content/20/6/1555
Autor:
Hikmat Assi, Maria G. Castro, Mariela A. Moreno Ayala, Yohei Mineharu, Pedro R. Lowenstein, Thomas J. Wilson, Shawn L. Hervey-Jumper, Marianela Candolfi
Publikováno v:
Tumors of the Central Nervous System
Tumors of the Central Nervous System ISBN: 9789400776012
Tumors of the Central Nervous System ISBN: 9789400776012
Glioblastoma Multiforme (GBM) is the most common and aggressive primary brain tumor. Every year ~22,000 patients are diagnosed with GBM in the US, and less than 5% survive 5 years post-diagnosis. Thus, novel therapeutic approaches are urgently needed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c137713a313ad6e30d0eafb5e93f91ae
https://link.springer.com/chapter/10.1007/978-94-007-7602-9_25
https://link.springer.com/chapter/10.1007/978-94-007-7602-9_25