Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Andrew J. Carroll"'
Autor:
Nick Telford, Nicole Dastugue, Michael R. Stratton, Paul Sinclair, Yang Li, Peter Vandenberghe, Richard J. Q. McNally, Fiona M. Ross, Patricia Jacobs, Nyla A. Heerema, Christine J. Harrison, Julian Borrow, Peter Van Loo, Olivia Joseph, Vikki Rand, Polly Talley, Philip J. Stephens, Bryan D. Young, Claire Schwab, Nick Bown, Mark Maddison, Andrew J. Carroll, Hazel M. Robinson, Anthony V. Moorman, Claudia Haferlach, Elli Papaemmanuil, Mike Griffiths, Peter J. Campbell, Lorraine Gaunt, Ben Robinson, Sarra Ryan, Sara Dyer, Manuel R. Teixeira, Jiqiu Cheng
Publikováno v:
Nature
Changes in gene dosage are a major driver of cancer, known to be caused by a finite, but increasingly well annotated, repertoire of mutational mechanisms1. This can potentially generate correlated copy-number alterations across hundreds of linked gen
Autor:
Yoav H. Messinger, Meenakshi Devidas, Andrew J. Carroll, Nyla A. Heerema, Rodney R. Higgins, Stephen P. Hunger
Publikováno v:
Cancer Genetics. 205:453-458
The rare translocation t(8;14)(q11.2;q32) has been described in patients with B-cell acute lymphoblastic leukemia (ALL), particularly patients with Down syndrome (DS). We describe patients with the t(8;14)(q11.2;q32) who were identified by the Childr
Publikováno v:
American journal of medical genetics. Part A. 167(7)
We describe a clinical encounter with family members that carry a balanced translocation involving chromosomes 15 and 21 roughly 50 years after the proband was diagnosed with partial trisomy 21 due to an unbalanced translocation. We discuss how these
Autor:
Rob Pieters, Maria Grazia Valsecchi, Cheryl L. Willman, Christine J. Harrison, Stephen P. Hunger, Meenakshi Devidas, P De Lorenzo, Nyla A. Heerema, Richard C. Harvey, ZoAnn E. Dreyer, Anthony V. Moorman, Andrew J. Carroll
Publikováno v:
Leukemia, 28(2), 428-430. Nature Publishing Group
Acute lymphoblastic leukemia (ALL) in infants less than one year of age is characterized by a high frequency of rearrangements of the MLL gene (MLL-R) and poor prognosis. Infants with no MLL rearrangements (MLL-G) have a better outcome than those wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c87435642b12a32a6ce2177acb2774f
https://pure.eur.nl/en/publications/4d7f70b7-6d7d-4ecd-b68a-3b3c9a389596
https://pure.eur.nl/en/publications/4d7f70b7-6d7d-4ecd-b68a-3b3c9a389596
Autor:
Clara D. Bloomfield, Michael A. Caligiuri, Colin G. Edwards, James W. Vardiman, Guido Marcucci, Kellie J. Archer, Prasad Koduru, Jonathan E. Kolitz, Karl S. Theil, Krzysztof Mrózek, Andrew J. Carroll, Pamela J. Snyder, Thomas W. Prior, Richard A. Larson, Mark J. Pettenati
Publikováno v:
Journal of Clinical Oncology. 19:2482-2492
PURPOSE: To prospectively compare cytogenetics and reverse transcriptase–polymerase chain reaction (RT-PCR) for detection of t(8;21)(q22;q22) and inv(16)(p13q22)/t(16;16)(p13;q22), aberrations characteristic of core-binding factor (CBF) acute myelo
Autor:
Christine J. Harrison, Stephen P. Hunger, Mignon L. Loh, Anthony V. Moorman, Claire Schwab, Paul Sinclair, Andrew J. Carroll, Nyla A. Heerema
Publikováno v:
Blood. 128:1733-1733
Intrachromosomal amplification of chromosome 21 (iAMP21) defines a distinct cytogenetic subgroup of 2% childhood acute lymphoblastic leukaemia (ALL). iAMP21-ALL patients have precursor B-cell ALL, are older (median age 9 years), generally present wit
Autor:
Eunice S. Wang, Bayard L. Powell, Ann-Kathrin Eisfeld, Andrew J. Carroll, Clara D. Bloomfield, Karl Kroll, Krzysztof Mrózek, John C. Byrd, Deedra Nicolet, Jonathan E. Kolitz, Jessica Kohlschmidt, Richard Stone, James S. Blachly, Shelley Orwick, Albert de la Chapelle
Publikováno v:
Blood. 128:287-287
The classification of AML is based on the morphology of leukemic blasts, their immunophenotypes, and the presence of specific chromosomal abnormalities and selected gene mutations. It is widely acknowledged that some gene mutations are enriched in ce
Autor:
D. Jeanette Pullen, Michael D. Amylon, Jonathan J. Shuster, Bruce M. Camitta, Michael J. Borowitz, Michael P. Link, Julie A. Katz, Nancy R. Schneider, Andrew J. Carroll
Publikováno v:
Blood. 96:2543-2549
To further define the cytogenetic differences between B-cell lineage (B-lineage) acute lymphoblastic leukemia (ALL) and T-cell lineage ALL (T-ALL) and to determine the prognostic value of cytogenetics in childhood T-ALL, the blast cell karyotypes of
Autor:
Enrique A. Escalon, Ilan R. Kirsch, Sheila N. Jani-Sait, Andrew J. Carroll, Pieter J. de Jong, Peter D. Aplan, Junjie Wang
Publikováno v:
Proceedings of the National Academy of Sciences. 97:3497-3502
We have cloned the genomic breakpoints for a balanced t(14;21)(q11.2;q22) chromosomal translocation associated with T-cell acute lymphoblastic leukemia. Sequence analysis of the genomic breakpoints indicated that the translocation had been mediated b
Autor:
Robert G. Watts, Kelly Cox, Andrew J. Carroll, P. Nagesh Rao, Bethy Jackle, Elizabetta Abruzzese, Mary C. Steuterman, Mark J. Pettenati
Publikováno v:
Cancer Genetics and Cytogenetics. 105:164-167
We present two cases with hidden Philadelphia translocations that resulted from an insertion and a complex translocation. These cases were unusual in having the BCR/ABL fusion localized to chromosome 9q34. A review of cases with these uncommon presen