Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Michael S. Bereman"'
Publikováno v:
Analytical and bioanalytical chemistry. 412(22)
We employ shotgun proteomics and data-independent acquisition (DIA) mass spectrometry to analyze cerebrospinal fluid longitudinally collected from 14 amyotrophic lateral sclerosis (ALS) patients (8 males and 6 females). We perform three main analyses
Autor:
Michael J. MacCoss, Michael S. Bereman, Josh Eckels, Joshua Beri, Brendan MacLean, Cory Nathe, Vagisha Sharma
Publikováno v:
Journal of Proteome Research. 15:4763-4769
We report the development of a completely automated pipeline to monitor system suitability in bottom-up proteomic experiments. LC-MS/MS runs are automatically imported into Skyline and multiple identification-free metrics are extracted from targeted
Autor:
James C. Bonner, Gregory N. Parsons, Michael S. Bereman, Alexia J. Taylor, Christina D. McClure, Gina M. Hilton
Publikováno v:
Toxicology. 329:80-87
Toxicoproteomics is a developing field that utilizes global proteomic methodologies to investigate the physiological response as a result of adverse toxicant exposure. The aim of this study was to compare the protein secretion profile in lung broncho
Autor:
Colleen K. Van Pelt, Edward J. Hsieh, Michael S. Bereman, Thomas N. Corso, Michael J. MacCoss
Publikováno v:
Molecular & Cellular Proteomics. 12:1701-1708
We report the development and characterization of a novel, vendor-neutral ultra-high pressure-compatible (∼10,000 p.s.i.) LC-MS source. This device is the first to make automated connections with user-packed capillary traps, columns, and capillary
Publikováno v:
Analytical chemistry. 87(23)
We present a novel proteomic standard for assessing liquid chromatography-tandem mass spectrometry (LC-MS/MS) instrument performance, in terms of chromatographic reproducibility and dynamic range within a single LC-MS/MS injection. The peptide mixtur
Autor:
David C. Muddiman, Michael S. Bereman
Publikováno v:
Analytical and Bioanalytical Chemistry. 396:1473-1479
We report the results of abundant plasma protein depletion on the analysis of underivatized N-linked glycans derived from plasma proteins by nanoLC Fourier-transform ion cyclotron resonance mass spectrometry. N-linked glycan profiles were compared be
Publikováno v:
Analytical Chemistry. 81:1130-1136
We report the development of split-less nano-flow liquid chromatography mass spectrometric analysis of glycans chemically cleaved from glycoproteins in plasma. Porous graphitized carbon operating under reverse-phase conditions and an amide-based stat
Autor:
Caleb J. Porter, Michael S. Bereman
Publikováno v:
Analytical and bioanalytical chemistry. 407(22)
We present a novel strategy based on data independent acquisition coupled to targeted data extraction for the detection and identification of site specific modifications of targeted peptides in a completely unbiased manner. This method requires prior
Autor:
Michael S. Bereman
Publikováno v:
Proteomics. 15(5-6)
With advances in liquid chromatography coupled to tandem mass spectrometry technologies combined with the continued goals of biomarker discovery, clinical applications of established biomarkers, and integrating large multiomic datasets (i.e. "big dat
Autor:
Yuval Boss, Michael J. MacCoss, Brendan MacLean, Michael S. Bereman, Nick Shulman, Andrew N. Hoofnagle, Richard J. Johnson, James G. Bollinger
Publikováno v:
Journal of the American Society for Mass Spectrometry. 25(4)
Statistical process control (SPC) is a robust set of tools that aids in the visualization, detection, and identification of assignable causes of variation in any process that creates products, services, or information. A tool has been developed terme