Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Pan Deng"'
Publikováno v:
Drug Metabolism and Disposition. 39:1058-1069
Amiodarone is recognized as an effective drug in the treatment of arrhythmias. Previous experiments demonstrated that mono-N-desethylamiodarone (MDEA) was the major circulating metabolite in humans. In addition, dealkylation, hydroxylation, and deami
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 117
TPN729 has been reported as a novel phosphodiesterase type 5 (PDE5) inhibitor to treat erectile dysfunction, and is currently being tested in clinical trials. In addition to the potent inhibition against PDE5, TPN729 is regarded as a better alternati
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 989
Capecitabine (Cape) is a prodrug that is metabolized into 5'-deoxy-5-fluorocytidine (DFCR), 5'-deoxy-5-fluorouridine (DFUR), and 5-fluorouracil (5-FU) after oral administration. A liquid chromatography-tandem mass spectrometry method for the simultan
Publikováno v:
Rapid communications in mass spectrometry : RCM. 27(21)
GLS4 is a heteroaryldihydropyrimidine compound that inhibits hepatitis B virus (HBV) replication by drug-induced depletion of nucleocapsids. It is currently undergoing clinical trials in China to treat HBV infection. The aim of this study was to iden
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 860(1)
A sensitive and selective ion-pair liquid chromatography-tandem mass spectrometric method (IP-LC-MS/MS) for the simultaneous determination of amodiaquine (AQ) and its active metabolite, N-desethylamodiaquine (AQm), in human blood has been developed a