Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Pan Deng"'
Publikováno v:
Nanomedicine : nanotechnology, biology, and medicine. 14(6)
This paper reports the multiplexed monitoring of two promising biomarkers, beta-amyloid (Aβ42) and total tau (T-tau), in both buffer and cerebrospinal fluid (CSF) for Alzheimer's disease (AD) using label-free optical nanosensors. It has been found t
Autor:
Mandapati V. Ramakrishnam Raju, Teresa W.-M. Fan, Zhen Qi, Ramon C. Sun, Ronald C. Bruntz, Richard M. Higashi, Pan Deng, Andrew N. Lane, Michael H. Nantz
Publikováno v:
The Analyst. 143(1)
The extensive range of chemical structures, wide range of abundances, and chemical instability of metabolites present in the metabolome pose major analytical challenges that are difficult to address with existing technologies. To address these issues
Publikováno v:
Rapid Communications in Mass Spectrometry. 27:2483-2492
Rationale GLS4 is a heteroaryldihydropyrimidine compound that inhibits hepatitis B virus (HBV) replication by drug-induced depletion of nucleocapsids. It is currently undergoing clinical trials in China to treat HBV infection. The aim of this study w
Publikováno v:
Analytica chimica acta. 925
Diacylglycerols (DAGs) are important lipid intermediates and have been implicated in human diseases. Isomerism complicates their mass spectrometric analysis; in particular, it is difficult to identify fatty acid substituents and locate the double bon
Publikováno v:
Biomedical Chromatography. 27:34-38
A rapid and sensitive analytical method based on liquid chromatography coupled to tandem mass spectrometry detection with positive ion electrospray ionization was developed for the determination of febuxostat in human plasma using d(7) -febuxostat as
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 2, Iss 2, Pp 159-167 (2012)
Ultraperformance liquid chromatography/quadrupole time-of-flight mass spectrometry (UPLC/Q-TOF MS) was used to characterize ornidazole metabolites in human bile after intravenous doses. A liquid chromatography tandem mass spectrometry (LC–MS/MS) as
Publikováno v:
Bioanalysis. 7(19)
Sensitive and reliable analysis of endogenous compounds is critically important for many physiological and pathological studies. Methods based on LC–MS have progressed to become the method of choice for analyzing endogenous compounds. However, the
Publikováno v:
Drug Metabolism and Disposition. 39:1058-1069
Amiodarone is recognized as an effective drug in the treatment of arrhythmias. Previous experiments demonstrated that mono-N-desethylamiodarone (MDEA) was the major circulating metabolite in humans. In addition, dealkylation, hydroxylation, and deami
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 52:571-579
An ion-pair reversed phase liquid chromatography–tandem mass spectrometry (LC–MS/MS) method has been developed for the quantification of a phosphorothioate oligonucleotide (PS-OGN) PF-ODN and its metabolites 5′N-1/3′N-1, 5′N-2 and 5′N-3 i
Publikováno v:
Academic Journal of Second Military Medical University. 28:326-330