Zobrazeno 11 - 19
of 19
pro vyhledávání: '"Pan Deng"'
Publikováno v:
Bioanalysis. 1:187-203
Liquid chromatography–tandem mass spectrometry (LC–MS/MS) has played an important role in quantitative bioanalytical assays. This review summarizes the recent progress on quantification of polar drugs in plasma with LC–MS/MS. Various types of p
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 49:848-852
A sensitive and selective liquid chromatography–tandem mass spectrometry method (LC–MS/MS) for the determination of tropisetron in human plasma was developed and validated over the concentration range of 0.100–100 ng/mL. Diphenhydramine was use
Publikováno v:
Journal of Chromatography B. 873:203-208
A highly sensitive liquid chromatography-tandem mass spectrometric (LC–MS/MS) method has been developed to determine rasagiline in human plasma. The analytical method utilized liquid–liquid extraction of plasma with n-hexane–dichloromethane–i
Publikováno v:
Chemical Research in Chinese Universities. 23:81-86
Microemulsion systems, composed of water, isopropyl myristate (IPM), polyoxyethylene sorbitan trioleate (Tween 85), and ethanol, were investigated as transdermal drug delivery vehicles for a lipophilic model drug(melo-xicam). The purpose of this stud
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 117
TPN729 has been reported as a novel phosphodiesterase type 5 (PDE5) inhibitor to treat erectile dysfunction, and is currently being tested in clinical trials. In addition to the potent inhibition against PDE5, TPN729 is regarded as a better alternati
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 989
Capecitabine (Cape) is a prodrug that is metabolized into 5'-deoxy-5-fluorocytidine (DFCR), 5'-deoxy-5-fluorouridine (DFUR), and 5-fluorouracil (5-FU) after oral administration. A liquid chromatography-tandem mass spectrometry method for the simultan
Publikováno v:
Bioanalysis. 4(1)
LC with atmospheric pressure ionization MS is essential to a large number of quantitative bioanalyses for a variety of compounds, especially nonvolatile or highly polar compounds. However, in many instances, weak ionization, poor LC retention and ins
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 877(10)
A selective and rapid method was developed and validated for determination of 6R-leucovorin (LV), 6S-leucovorin and 5-methyltetrahydrofolate (5-MeTHF) in human plasma using stereoselective liquid chromatography-tandem mass spectrometry. All analytes
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 860(1)
A sensitive and selective ion-pair liquid chromatography-tandem mass spectrometric method (IP-LC-MS/MS) for the simultaneous determination of amodiaquine (AQ) and its active metabolite, N-desethylamodiaquine (AQm), in human blood has been developed a
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