Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Richard Salvi"'
Publikováno v:
J Assoc Res Otolaryngol
Temporal resolution is essential for processing complex auditory information such as speech. In hearing impaired persons, temporal resolution, often assessed by detection of brief gaps in continuous sound stimuli, is typically poorer than in individu
Autor:
Dong Li, Haibo Shi, Hong Sun, Haiyan Jiang, Xuewen Wu, Weiluo Huang, Peng Li, Dalian Ding, Richard Salvi, Jintao Yu, Weidong Qi, Jianhui Zhang, Wenjuan Li, Fang Liu
Publikováno v:
J Neurophysiol
Auditory brain stem response (ABR) and compound action potential (CAP) recordings have been used in animal research to determine hearing sensitivity. Because of the relative ease of testing, the ABR test has been more commonly used in assessing cochl
Publikováno v:
The Journal of the Acoustical Society of America. 146(5)
It is well-established that excessive noise exposure can systematically shift audiometric thresholds (i.e., noise-induced hearing loss, NIHL) making sounds at the lower end of the dynamic range difficult to detect. An often overlooked symptom of NIHL
Autor:
Senthilvelan Manohar, Richard Salvi, Chet C. Sherwood, Joan S. Baizer, Keit Men Wong, Patrick R. Hof, Sandra F. Witelson, James F. Baker
Publikováno v:
The Anatomical Record. 301:862-886
The mammalian cochlear nuclei (CN) consist of two major subdivisions, the dorsal (DCN) and ventral (VCN) nuclei. We previously reported differences in the structural and neurochemical organization of the human DCN from that in several other species.
Autor:
S. Mitra, Dalian Ding, Mohammad Habiby Kermany, Kari Suzanne Kraus, Haiyan Jiang, Richard Salvi
Publikováno v:
Hearing Research. 302:74-82
Inner ear damage leads to nerve fiber growth and synaptogenesis in the ventral cochlear nucleus (VCN). In this study, we documented the relationship between hair cell loss patterns and synaptic plasticity in the chinchilla VCN using immunolabeling of
Autor:
Dalian Ding, Mohammad Habiby Kermany, Samson Jamesdaniel, Bo Hua Hu, Richard Salvi, Haiyan Jiang, Donald E. Coling
Publikováno v:
Journal of Proteomics. 75:410-424
Noise exposure is a major cause of hearing loss. Classical methods of studying protein involvement have provided a basis for understanding signaling pathways that mediate hearing loss and damage repair but do not lend themselves to studying large net
Publikováno v:
Hearing Research. 226:129-139
Ethacrynic acid (EA) significantly enhances the ototoxic effects of cisplatin. To gain insights into the mechanisms underlying Cis/EA ototoxicity, cochleas were labeled with several apoptotic markers. Cis/EA treatment caused extensive outer hair cell
Publikováno v:
Journal of the Association for Research in Otolaryngology : JARO. 17(2)
Poorer hearing in the presence of background noise is a significant problem for the hearing impaired. Ototoxic drugs, ageing, and noise exposure can damage the sensory hair cells of the inner ear that are essential for normal hearing sensitivity. The
Publikováno v:
Hearing Research. 206:64-73
Amino acid concentrations were measured in the cochlear nucleus for a group of 20 chinchillas: four each of control and 4, 8, 29, and 85 days after treatment with the ototoxic anti-tumor drug carboplatin (100 mg/kg, i.p.). The treated chinchillas sho
Publikováno v:
Acta Oto-Laryngologica. 124:35-41
Intratympanic or round window application of gentamicin is often used to alleviate disabling vertigo arising from unilateral Meniere's disease; however, treatment is often accompanied by hearing loss because the drug initially enters the cochlea befo