Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Massimo Pietropaolo"'
Autor:
Jacobo Nieto, Maria J. Redondo, Massimo Pietropaolo, Beatriz Castillo, Marcela Astudillo, Mustafa Tosur, Ashok Balasubramanyam
Publikováno v:
Pediatric Diabetes. 22:882-888
We aimed to study whether islet autoantibody type marks differential characteristics at the time of type 1 diabetes (T1D) diagnosis.We studied 711 children with newly diagnosed autoimmune T1D. We compared demographic (sex, age, race/ethnicity), clini
Autor:
Liping Yu, Michael P. Morran, Dorothy J. Becker, Howard W. Davidson, Shuai Huang, Andrew D Vonberg, Massimo Pietropaolo, Charles F. Verge, Roberto Gianani, Maria Acevedo-Calado, Susan L. Pietropaolo, Stephen S. Rich, Carla J. Greenbaum, Santiago Schnell, Aaron W. Michels
Publikováno v:
Diabetes
We identified autoantibodies (AAb) reacting with a variant IA-2 molecule (IA-2var) that has three amino acid substitutions (Cys27, Gly608, and Pro671) within the full-length molecule. We examined IA-2var AAb in first-degree relatives of type 1 diabet
Autor:
Marco Liguori, Shuai Huang, Eddie A. James, David Arribas-Layton, Richard J. Auchus, Aaron W. Michels, Qin Ouyang, Roberto Gianani, Anna Casu, Liping Yu, Maria Acevedo-Calado, Massimo Pietropaolo, Marco Songini, Michael P. Morran, Susan L. Pietropaolo
Publikováno v:
Diabetes Care
OBJECTIVE The characterization of diverse subtypes of diabetes is a dynamic field of clinical research and an active area of discussion. The objective of this study was to identify new antigenic determinants in the neuroendocrine autoantigen IA-2 (IC
Autor:
Ingrid Libman, Vincent C. Arena, Lei Zhou, Diego Ize-Ludlow, Massimo Trucco, Maribel Cedillo, Dorothy J. Becker, Massimo Pietropaolo
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 100:E82-E86
The current increase in childhood type 1 diabetes (T1D) and obesity has led to two conflicting hypotheses and conflicting reports regarding the effects of overweight on initiation and spreading of islet cell autoimmunity vs earlier clinical manifesta
Autor:
Gilbert S. Omenn, Anna Casu, Ying Jian Zhang, Dorothy J. Becker, Patrick W. Nelson, Michael P. Morran, Vincent C. Arena, Leslie S. Satin, Massimo Pietropaolo, Susan L. Pietropaolo, Massimo Trucco
Publikováno v:
Endocrinology. 151:2528-2537
The objective of this study was to determine whether antigenic determinants localized within the extracellular domain of the neuroendocrine autoantigen tyrosine phosphatase-like protein IA-2 are targets of humoral responses in type 1 diabetes (T1DM).
Autor:
Natalie, Hecht Baldauff, Hala, Tfayli, Wenxiu, Dong, Vincent C, Arena, Nursen, Gurtunca, Massimo, Pietropaolo, Dorothy J, Becker, Ingrid M, Libman
Publikováno v:
Pediatric diabetes. 17(4)
To explore racial differences in adiponectin, and leptin and their relationship with islet autoimmunity in children with new-onset type 1 diabetes (T1D).Medical records were reviewed from a cohort of new-onset clinically diagnosed T1D subjects matche
Autor:
Ronald E. LaPorte, Allan L. Drash, Massimo Trucco, Massimo Pietropaolo, Susan L. Pietropaolo, Dorothy J. Becker, Karen Riley, Ingrid Libman, Shui Yu, Sati Mazumdar
Publikováno v:
Pediatric Diabetes. 6:184-192
The discovery of islet cell antibodies (ICAs) was the prelude to the understanding that type 1 diabetes mellitus (T1DM) is a chronic autoimmune disease. The issue regarding whether or not the measurement of ICAs should be completely replaced by bioch
Autor:
Janice S. Dorman, Anita M. Nucci, Yue-Fang Chang, Ronald E. LaPorte, Ann R. Steenkiste, Limin Wang, Massimo Pietropaolo, Ze Yang, Shui-Xian Shen, Binyou Wang, Elsa S. Strotmeyer
Publikováno v:
Diabetes Research and Clinical Practice. 65:283-292
Infant milk and food introduction may be linked to type 1 diabetes risk in high incidence populations. Dietary data through age 12 months was collected for 247 type 1 diabetic cases and 443 controls in China, a low incidence population, to determine
Autor:
George S. Eisenbarth, Richard J. Bartlett, Alarico Fernandez, Massimo Pietropaolo, Simon T. Bennett, Alberto Pugliese, Camillo Ricordi, Markus Zeller, Laura J. Zalcberg, Dhavalkumar D. Patel
Publikováno v:
Nature Genetics. 15:293-297
Type 1, or insulin-dependent diabetes mellitus (IDDM) is an autoimmune disease associated with loss of tolerance to several pancreatic islet cell molecules, including insulin, glutamic acid decarboxylase (GAD), ICA69 and the tyrosine phosphatase IA-2
Autor:
Spoletini, MARIA LUISA, Zampetti, Simona, Campagna, Giuseppe, Marandola, Lidia, Capizzi, Marco, Buzzetti, Raffaella, Imdiab Study Group, For The Imdiab Study Group, Massimo, Pietropaolo
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61331 (2013)
PLoS ONE
PLoS ONE
The incidence of type 1 diabetes has, progressively, increased worldwide over the last decades and also in Continental Italian population. Previous studies performed in northern European countries, showed, alongside a general increase in the disease