Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Yutaro Kaneko"'
Autor:
Yutaro Kaneko, Toshiyuki Inazu, and Toru Mimura, Kwan-Jun Jeon,†,‡, Toshiyuki Uryu, Kaname Katsuraya
Publikováno v:
Journal of the American Chemical Society. 122:12536-12541
A new method is found for the detection of interactions between a highly anti-HIV (human immunodeficiency virus) active curdlan sulfate (CS) and a HIV peptide with the aid of NMR spectroscopy. To elucidate the action mechanism of the anti-HIV activit
Autor:
Rong Lu, Hideki Nakashima, Yutaro Kaneko, Tetsuo Miyakoshi, Naoki Yamamoto, Toshiyuki Uryu, R. Aragaki, Mariappan Premanathan, Toru Mimura, Takuma Yoshida
Publikováno v:
Carbohydrate Polymers. 43:47-54
The specific biological activities such as blood coagulant, anti-tumor, anti-HIV, and anticoagulant activities of a Chinese lacquer polysaccharide, a branched acidic polysaccharide, before and after sulfonation were investigated. The lacquer polysacc
Publikováno v:
Macromolecules. 32:8319-8324
An AIDS (acquired immunodeficiency syndrome) drug, azidothymidine (AZT), was bound by an ester bond onto curdlan sulfate having both anti-HIV activity and the property of accumulating in lymphoid tissues to produce a series of biodegradable AZT−ali
Autor:
Yoonsoung Choi, Yutaro Kaneko, Bin Yu, Takashi Yoshida, Eriko Aragaki, Kazuyuki Hattori, Toru Mimura, Naoki Yamamoto, Tsukasa Akasaka, Hideki Nakashima, Toshiyuki Uryu, Mariappan Premanathan
Publikováno v:
Journal of Polymer Science Part A: Polymer Chemistry. 37:789-800
Anti-HIV (human immunodeficiency virus) active polymethacrylates having pendant sulfated oligosaccharides were synthesized, and the relationship between structures and biological activities of the polymethacrylates was examined. Acetylated 1-O-methac
Autor:
Kenichi Hatanaka, Kei Matsuzaki, Akira Kai, Tohru Mimura, Masayuki Kikawa, Hiroko Karasawa, Yutaro Kaneko
Publikováno v:
Carbohydrate Polymers. 35:271-278
Biosynthesis of branched glucan by Pestalotiopsis from media containing D-(1- 13 C)glucose, D-(2- 13 C)glucose, D-(4- 13 C)glucose, D-(6- 13 C)glucose or a mixture of D-(1- 13 C)glucose and D-(2- 13 C)glucose was carried out to elucidate biosynthetic
Publikováno v:
Polymer Journal. 30:106-112
The interactions between chondroitin-6-sulfate (COS) and lysine derivatives such as oligolysines, polylysines (PL), and copolylysines were examined to elucidate functions of bioactive sulfated glycosaminoglycans by means of NMR spectroscopy. Gellike
Publikováno v:
Polymer Journal. 30:31-36
Azidothymidine (AZT) was introduced into curdlan by biodegradable ester bond to give AZT-bound curdlan (AZT-curdlan) in order to aim at releasing AZT from the polymer backbone by an enzymatic hydrolysis in living organs. Structure of the AZT-curdlan
Autor:
Kaname Katsuraya, Ying Gao, Toru Mimura, Toshiyuki Uryu, Yutaro Kaneko, Hideki Nakashima, Akiko Fukuda
Publikováno v:
Macromolecules. 30:3224-3228
To investigate the relationship between the structure of curdlan sulfate with β-[1→3]-d-glucan as main chain and the anti-HIV activity, three regioselective substituted curdlan sulfates (CS's), i.e...
Autor:
Takashi Yoshida, Naoki Yamamoto, Toshiyuki Uryu, Rong Lu, Mitsuru Osawa, Toru Mimura, Yoon Soung Choi, Hideki Nakashima, Kazuyuki Hattori, Yutaro Kaneko, Byoung Won Kang
Publikováno v:
Polymer Journal. 29:374-379
Synthesis of Sulfated Deoxy-Ribofuranans Having Selective Anti-AIDS Virus Activity by Ring-Opening Copolymerization of 1,4-Anhydro Ribose Derivatives
Publikováno v:
Sen'i Gakkaishi. 53:533-539
To elucidate the action mechanism of bioactive sulfated polysaccharides which exhibited anticoagulant and antiviral activities, interactions of an anticoagulant polysaccharide heparin (Hep) with polylysine (PL) which can be regarded as a model compou