Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Yiwei Chu"'
Autor:
Robert S. Munford, Wei Jiang, Michael Goodwin, Yiwei Chu, Benkun Zou, Jianguo Tang, Danial Saleem, Mingfang Lu
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
Oxidized phospholipids have diverse biological activities, many of which can be pathological, yet how they are inactivated in vivo is not fully understood. Here, we present evidence that a highly conserved host lipase, acyloxyacyl hydrolase (AOAH), c
Autor:
Yuanyuan Wei, Mingfang Lu, Alan W. Varley, Qiang Zhao, Yiwei Chu, Guojun Qian, Wenjiao Zeng, Jintao Feng, Xiaobo Li, Jianguo Tang, Ting Liu, Robert S. Munford, Xiaofang Cheng, Benkun Zou, Wei Jiang
Publikováno v:
iScience
iScience, Vol 24, Iss 9, Pp 103004-(2021)
iScience, Vol 24, Iss 9, Pp 103004-(2021)
Summary Although microbe-associated molecular pattern (MAMP) molecules can promote cholesterol accumulation in macrophages, the existence of a host-derived MAMP inactivation mechanism that prevents foam cell formation has not been described. Here, we
Autor:
Jianguo Tang, Wei Jiang, Benkun Zou, Yiwei Chu, Robert S. Munford, Mingfang Lu, Danial Saleem, Michael Goodwin
Oxidized phospholipids have diverse biological activities, many of which can be pathological, yet how they are inactivatedin vivois not fully understood. Here we present evidence that a previously unsuspected host lipase, acyloxyacyl hydrolase (AOAH)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d47a6f82cd7a472c2ec0a88416b8081
https://doi.org/10.1101/2021.07.26.453786
https://doi.org/10.1101/2021.07.26.453786
Autor:
Chunlai Lu, Lin Wang, Fengkai Xu, Jie Gu, Ronghua Liu, Wei Mao, Yiwei Chu, Qiaoliang Zhu, Zhonghe Liu, Di Ge
Publikováno v:
International Journal of Biological Sciences. 15:127-137
Lung cancer is one of the most frequent malignant tumors, with the top morbidity and mortality, in China. Calpain family regulates cellular processes including migration and invasion. However, the role of Calpain-2 in non-small cell lung cancer (NSCL
Publikováno v:
Cell Research. 26:850-853
Bifunctional αHER2/CD3 RNA-engineered CART-like human T cells specifically eliminate HER2 + gastric cancer
Autor:
Robert M. Hoffman, Meng Yang, Chunjie Li, Ping Chen, Yongfu Pan, Dongping Wei, Yupei Liang, Yiwei Chu, Pei Li, Yanan Jiang, Lijun Jia, Hui Qi, Tao Hu, Ziming Dong, Ping Zhang, Lak Shin Jeong
Publikováno v:
Oncotarget
Liver cancer is the second-most frequent cause of cancer death in the world and is highly treatment resistant. We reported previously that inhibition of neddylation pathway with specific NAE inhibitor MLN4924, suppressed the malignant phenotypes of l
Autor:
Wei Lin, Yuanfang Zhang, Guozeng Wang, Lihuan Du, Ning Jiang, Gang Chen, Jing Qian, Yiwei Chu, Jingcun Zheng
Publikováno v:
Journal of Photochemistry and Photobiology B: Biology. 133:1-10
We previously developed a novel photosensitizer, chlorophyllin e4, and found that chlorophyllin e4 mediated-PDT could kill 5637 and T24 cells by inducing apoptotic cell death. Here, we further investigated the new mechanism of autophagy and determine
Autor:
Jing Li, Han Han, Wenhong Zhang, Wenjiao Zeng, Benkun Zou, Zihui Tang, Yiwei Chu, Ning Zhu, Jing Qian, Tianqing Chu, Rui He, Jie Gu, Dapeng Yan, Mingfang Lu, Qian Yang, Guojun Qian, Weiying Mao, Wei Jiang
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 13, Iss 6, p e1006436 (2017)
PLoS Pathogens, Vol 13, Iss 6, p e1006436 (2017)
Pulmonary infection is the most common risk factor for acute lung injury (ALI). Innate immune responses induced by Microbe-Associated Molecular Pattern (MAMP) molecules are essential for lung defense but can lead to tissue injury. Little is known abo
Autor:
Jing Qian, Pei Jiang, Xiujuan Zheng, Shudao Xiong, Yijie Zheng, Yiwei Chu, Ronghua Liu, Xiaoming Liu
Publikováno v:
Free Radical Biology and Medicine. 52:1307-1317
Glucocorticoids (GCs) are among the most widely used and effective therapies for many chronic inflammatory diseases. Although attempts have been made to identify important protein-coding genes and pathways involved in the anti-inflammatory effect of
Publikováno v:
International Immunopharmacology. 11:212-219
Paclitaxel has become one of the most effective and widely used chemotherapeutic agents over the past decades. Although it has shown promise to selectively deplete regulatory T (Treg) cells in our previous study, the underlying molecular mechanism re