Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Wylie, J"'
Publikováno v:
Neurogastroenterology & Motility. 2:23-30
The genesis of lower esophageal sphincter (LES) pressure in anesthetized opossums is a myogenic phenomenon without excitatory neural input. The mechanism responsible for generating phasic LES pressure phenomena in unanesthetized opossums, however, is
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 263:G953-G959
We studied the propagation of phasic contractions initiated by tetraethylammonium (TEA, 1-10 mM), high K+ concentration (10-30 mM), and bethanechol (10(-6) to 10(-2) M) in a whole organ in vitro preparation of the opossum smooth muscle esophagus. TEA
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 262:G567-G571
The aim of the present study was to 1) characterize nicotine-induced peristalsis in the feline esophagus and 2) determine the site of action of nicotine. Experiments were done on ketamine-sedated cats. Esophageal contractions were measured using a mu
Publikováno v:
Gut. 33:7-10
The oesophageal acid clearance time was evaluated in 10 healthy volunteers of 'small' boluses of 0.5 and 1 ml and 'minute' boluses of 0.05 and 0.1 ml 0.1 N HCl, as well as 0.1 and 1 ml 0.01 and 0.001 N HCl. Swallow rate was normalised at q 60 seconds
Autor:
Ronald C. Arndorfer, Sushil K. Sarna, James F. Helm, Raymond G. Hoffmann, S. L. Bro, Wylie J. Dodds
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 261:G377-G383
We evaluated the control of phasic contractions in opossum esophageal circular smooth muscle by determining the contractile response in vitro to agents that cause membrane depolarization and excitation by different mechanisms. Transverse muscle strip
Autor:
Beverley Greenwood, Wylie J. Dodds, Joseph S. Davison, Timothy R. Koch, Thomas Doolittle, Norman A. See
Publikováno v:
Gastroenterology. 98:1509-1517
Previous studies in the ferret demonstrated that vagal nerve stimulation induced an atropine-resistant water secretion. Substance P and vasoactive intestinal polypeptide are possible mediators of this secretory response. The objectives of this study
Publikováno v:
Digestive Diseases and Sciences. 35:567-576
In this study, we evaluated the mechanism of action whereby cholecystokinin increases spike-burst rate of the opossum sphincter of Oddi (SO). Each spike burst corresponds to a peristaltic SO contraction. Two types of animal preparations were evaluate
Autor:
Itsuo Takahashi, R.D. Layman, Wylie J. Dodds, William Y. Chey, Nobuyoshi Hanyu, Walter J. Hogan
Publikováno v:
Gastroenterology. 98(5 Pt 1)
The present study evaluated the mechanism of cholecystokinin-induced gallbladder contraction in awake opossums. Each of 19 chronic animal preparations had an indwelling gallbladder cannula for monitoring changes in gallbladder volume and a jugular ca
Publikováno v:
New England Journal of Medicine. 310:284-288
We studied clearance of acid from the esophagus and esophageal emptying in normal subjects. A 15-ml bolus of 0.1 N hydrochloric acid (pH 1.2) radiolabeled with [99mTc]sulfur colloid was injected into the esophagus, and the subject swallowed every 30
Autor:
Wylie J. Dodds, Richard J. Gilbert
Publikováno v:
Digestive Diseases and Sciences. 32:1130-1135
We assessed the characteristics of muscarinic neural transmission in the vagal inhibitory pathway to the lower esophageal sphincter (LES) of anesthetized opossums. LES relaxation was induced by electrical stimulation of the cervical vagus. Measuremen