Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Wungki Park"'
Publikováno v:
Cancer Metastasis Rev
Pancreas ductal adenocarcinoma (PDAC) is the third most common cause of cancer death in the USA. While other cancers with historically poor prognoses have benefited from new immunotherapies and targeted agents, the 5-year survival rate for PDAC patie
Publikováno v:
JAMA
IMPORTANCE: Pancreatic ductal adenocarcinoma (PDAC) is a relatively uncommon cancer, with approximately 60 430 new diagnoses expected in 2021 in the US. The incidence of PDAC is increasing by 0.5% to 1.0% per year, and it is projected to become the s
Publikováno v:
Cellular Signalling. 25:1288-1300
Curcumin as an anticancer agent was investigated in regards to its ability to regulate the switching of cancer cells from survival to necrotic cell death. At higher concentrations, curcumin induced ROS production leading to JNK and p38 phosphorylatio
Autor:
Lydia Koenig, Wungki Park, Daniel Rycroft, Yuxiang Wang, Dong M. Shin, Sujin Yun, Steve Holmes, Sreenivas Nannapaneni, Hyung Ju C. Shin, Michael Steward, Thil Batuwangala, Hongzheng Zhang, Mourad Tighiouart, Lin Pan, Zhuo Georgia Chen
Publikováno v:
International Journal of Cancer. 131:956-969
An antibody simultaneously targeting epidermal growth factor receptor (EGFR) and vascular endothelial growth factor (VEGF), two major tumor growth-driving machineries, may provide a novel effective strategy for optimizing tumor targeting and maximizi
Autor:
Vaia Florou, Deukwoo Kwon, Darcy A. Kerr, Efrosyni Sfakianaki, Jonathan C. Trent, Andrew E. Rosenberg, Ty K. Subhawong, Despina Kolonias, Jaime R. Merchan, Wungki Park, Eric D. Wieder, Krishna V. Komanduri, Matteo Trucco, Breelyn A. Wilky
Publikováno v:
Journal of Clinical Oncology. 36:11547-11547
11547Background: Inhibition of programmed-death 1 (PD1) by pembrolizumab (P) produced overall response rates (ORR) of 19% in advanced STS [SARC028]. Vascular endothelial growth factor (VEGF) suppre...
Publikováno v:
Cancer Research. 72:2273-2273
Curcumin as an anticancer agent was investigated to study how it can regulate cancer cells’ destination to either apoptosis or autophagy. At higher concentration, curcumin induced ROS production leading to JNK and p38 phosphorylation in DU-145 pros
Autor:
So Y. Kim, Joo Hang Kim, Wungki Park, Jae J. Song, Jina Kim, Hyo R. Yoon, Kijae Hong, Hye Jin Choi, Seeun Oh, Sujin Kang
Publikováno v:
Cancer Research. 71:C42-C42
Previously, we have shown that p38-HSP27 acted as modulators from survival to death depending on the apoptotic strength in prostate cancer cells. For example, if the apoptotic strength is in the moderate range, p38-HSP27 acted to increase Akt catalyt