Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Vedaldi D"'
Autor:
Anna Carbone, Patrizia Diana, Silvia Tisi, Ignazio Castagliuolo, Libero Caracausi, Girolamo Cirrincione, Alessia Salvador, Francesco Dall'Acqua, Paola Barraja, Daniela Vedaldi, Alessandra Montalbano, Paola Brun
Publikováno v:
ChemMedChem. 6:1238-1248
Heteroanalogues of angelicin, pyrrolo[3,2-h]quinazolines, were synthesized with the aim of obtaining new potent photochemotherapeutic agents. Many derivatives caused a significant decrease in cell proliferation in several human tumor cell lines after
Autor:
Girolamo Cirrincione, Alessia Salvador, Francesco Dall'Acqua, Paola Barraja, Daniela Vedaldi, Alessandra Montalbano, Giampietro Viola, Patrizia Diana, Giuseppe Basso, Anna Carbone
Publikováno v:
Bioorganic & Medicinal Chemistry. 19:2326-2341
Pyrrolo[3,4- h ]quinolin-2-ones were synthesized as nitrogen isosters of the angular furocoumarin angelicin, with the aim of obtaining new photochemotherapeutic agents with increased antiproliferative activity and lower undesired toxic effects. A ver
Autor:
Diana Patrizia, Giampietro Viola, Girolamo Cirrincione, Virginia Spanò, Francesco Dall'Acqua, Paola Barraja, Daniela Vedaldi, Anna Carbone, Alessia Salvador
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:1711-1714
A convenient synthesis of the pyrano[2,3-e]isoindol-2-one ring system, an heteroanalogue of angelicin, is reported. Our synthetic approach consists of the annelation of the pyran ring on the isoindole moiety using 5-dialkylamino- or 5-hydroxymethylen
Autor:
Paola Barraja, Daniela Vedaldi, Paola Brun, Alessia Salvador, Anna Carbone, Virginia Spanò, Patrizia Diana, Barbara Parrino, Alessandra Montalbano, Girolamo Cirrincione
Publikováno v:
European journal of medicinal chemistry. 102
A new series of pyrazolo[3,4-h]quinolines, heteroanalogues of angelicin was conveniently prepared with a broad substitution pattern. A large number of derivatives was obtained and the cellular photocytotoxicity was evaluated in vitro against 5 differ
Autor:
Giampietro Viola, Stefano Chimichi, Barbara Cosimelli, Marco Boccalini, Daniela Vedaldi, Francesco Dall'Acqua
Publikováno v:
Tetrahedron Letters. 43:7473-7476
A new class of compounds analogues of geiparvarin is described: aldolic condensation of 3(2H)-furanones and 7-(2-oxoethoxy)coumarins followed by a very efficient dehydration protocol led to the title compounds which show good antitumoral activity aga
Autor:
Patrizia Diana, Anna Carbone, Virginia Spanò, Paola Barraja, Daniela Vedaldi, Alessandra Montalbano, Barbara Parrino, M Muscarella, Alessia Salvador, Girolamo Cirrincione
Derivatives of new ring systems 11H-pyrido[3',2':4,5]pyrrolo[3,2-c]cinnoline and pyrido[3',2':4,5]pyrrolo[1,2-c][1,2,3]benzotriazine have been prepared from the key intermediates 2-(1H-pyrrolo[2,3-b]pyridin-2-yl)anilines in excellent yields (94-99%)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46fb0014c8c524b05fb4acca58a96803
http://hdl.handle.net/10447/102794
http://hdl.handle.net/10447/102794
Autor:
Girolamo Cirrincione, Ignazio Castagliuolo, Alessia Salvador, Libero Caracausi, Giorgio Palù, Patrizia Diana, Paola Barraja, Daniela Vedaldi, Paola Brun, Francesco Dall'Acqua, Anna Carbone, Alessandra Montalbano
In the search for new photochemotherapeutic agents, a series of derivatives of the ring system pyrrolo[3,2-h]quinoline--bioisosters of the angular furocoumarin angelicin--were synthesized through a four-step synthetic approach, in reasonable overall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88da20c1b189b679b3f317089fdf0a14
http://hdl.handle.net/10447/51294
http://hdl.handle.net/10447/51294
THIOPYRANO[2,3-E]INDOL-2-ONES: ANGELICIN HETEROANALOGUES WITH POTENT PHOTOANTIPROLIFERATIVE ACTIVITY
Autor:
Patrizia Diana, Giampietro Viola, Alessia Salvador, Alessandra Montalbano, Girolamo Cirrincione, Paola Barraja, Daniela Vedaldi, Anna Carbone, Francesco Dall'Acqua
A new class of compounds, the thiopyrano[2,3-e]indol-2-ones, bioisosters of the angular furocoumarin angelicin, was synthesized with the aim of obtaining new photochemotherapeutic agents. In particular 7,8-dimethyl-thiopyranoindolone 6c s showed a re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::573c605814c6c64b997aa389120a5017
https://hdl.handle.net/11567/1024312
https://hdl.handle.net/11567/1024312
Autor:
Giampietro Viola, Patrizia Diana, Girolamo Cirrincione, Gaetano Dattolo, Francesco Dall'Acqua, Paola Barraja, Daniela Vedaldi, Alessandra Montalbano
A new class of compounds, the pyrrolo[2,3-h]quinolin-2-ones, nitrogen isosters of the angular furocoumarin Angelicin, was synthesized with the aim of obtaining new photochemotherapeutic agents with increased antiproliferative activity and lower undes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31f388ebf421ac7dda26fd0bd0aea9fa
http://hdl.handle.net/11577/2447640
http://hdl.handle.net/11577/2447640