Zobrazeno 1 - 10
of 241
pro vyhledávání: '"Unsworth, A"'
Autor:
Larry D. Unsworth, Marcello Tonelli, Yuhao Ma, Narges Hadjesfandiari, Michael R. Doschak, Dana V. Devine
Publikováno v:
Langmuir. 37:12335-12345
Carbamylation of blood proteins is a common post-translational modification that occurs upon kidney dysfunction that is strongly associated with deleterious outcomes for patients treated using hemodialysis. In this study, we focused on the removal of
Publikováno v:
ACS Omega
ACS Omega, Vol 6, Iss 4, Pp 3079-3089 (2021)
ACS Omega, Vol 6, Iss 4, Pp 3079-3089 (2021)
Protein carbamylation has been linked with diseases commonly associated with patients with reduced kidney function. Carbamylated human serum albumin (cHSA), which has been proven to be nephrotoxic and associated with heart failure for chronic kidney
Publikováno v:
Organic & Biomolecular Chemistry. 19:1404-1411
A side chain insertion method for the ring expansion of lactams into macrocyclic thiolactones is reported, that can also be incorporated into Successive Ring Expansion (SuRE) sequences. The reactions are less thermodynamically favourable than the ana
Autor:
Emilie Marotte, Kleopas Y. Palate, Ryan G. Epton, William P. Unsworth, Katie J. Lamb, Aggie Lawer, Thomas C. Stephens, Jade K. Sangha, Jason M. Lynam, Mahendar Lodi
Publikováno v:
CHEMISTRY-A EUROPEAN JOURNAL
Chemistry (Weinheim an Der Bergstrasse, Germany)
Chemistry (Weinheim an Der Bergstrasse, Germany)
The outcome of ring‐expansion reactions based on amino/hydroxyacid side‐chain insertion is strongly dependent on ring size. This manuscript, which builds upon our previous work on Successive Ring Expansion (SuRE) methods, details efforts to bette
Publikováno v:
Journal of Visualized Experiments.
Identifying ligands specific to therapeutically significant cell receptors is crucial for many applications, including the design and development of new therapeutics. Mas related G-protein receptor-X2 (MRGPRX2) is an important receptor that regulates
Autor:
Philip J. Gunning, Asterios Triantafyllou, Steve Barrett, Caroline I. Smith, P Harrison, Janet M. Risk, Peter Gardner, Richard Shaw, P. Unsworth, Barnaby G. Ellis, Conor A. Whitley, Safaa Al Jedani, Peter Weightman
Publikováno v:
ANALYST
The Analyst
The Analyst
A novel machine learning algorithm is shown to accurately discriminate between oral squamous cell carcinoma (OSCC) nodal metastases and surrounding lymphoid tissue on the basis of a single metric, the ratio of Fourier transform infrared (FTIR) absorp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dae56cc4947b96b49a5dc166903ac3b
Publikováno v:
The New phytologistREFERENCES. 127(2)
SUMMARY Young ash trees (Fraxinus excelsior L.) growing in the field were exposed to episodes of 150 nl 1-1 ozone, or to clean air, in open-top chambers at the University of Nottingham, Sucton Bonington Campus, UK, in the summer of 1992. The episodes
Publikováno v:
Scopus-Elsevier
summary Young ash trees (Fraxinus excelsior L.) growing in the field were exposed to episodes of 150 nl 1−1 ozone, or to clean air, in open-top chambers at the University of Nottingham, Sutton Bonington Campus, UK, May–October, 1992–1994. The e
Autor:
Julie A. Lovegrove, Amanda J. Unsworth, Parvathy Sasikumar, Alexander R. Stainer, Alexander P. Bye, Marcus J. Tindall, Lisa M. Holbrook, Jonathan M. Gibbins
Publikováno v:
TH Open, Vol 03, Iss 03, Pp e244-e258 (2019)
TH Open: Companion Journal to Thrombosis and Haemostasis
TH Open: Companion Journal to Thrombosis and Haemostasis
Quercetin, a dietary flavonoid, has been reported to possess antiplatelet activity. However, its extensive metabolism following ingestion has resulted in difficulty elucidating precise mechanisms of action. In this study, we aimed to characterize the
Autor:
Hannu Häkkinen, J. Daniel Padmos, Renee W. Y. Man, Sami Kaappa, Ryohei Tomihara, Shinjiro Takano, Sami Malola, Cathleen M. Crudden, Kennedy Ayoo, Phillip J. Unsworth, Cao-Thang Dinh, Masakazu Nambo, Patrick J. Garrett, Tatsuya Tsukuda, Kimberly M. Osten, Edward H. Sargent, J. Hugh Horton, Mina R. Narouz, Kirsi Salorinne
Publikováno v:
Nature Chemistry. 11:419-425
Magic-number gold nanoclusters are atomically precise nanomaterials that have enabled unprecedented insight into structure-property relationships in nanoscience. Thiolates are the most common ligand, binding to the cluster via a staple motif in which