Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Tore Bengtsson"'
Autor:
Claes-Göran Östenson, Joris Hoeks, Tore Bengtsson, Anastasia V. Kalinovich, Carina Halleskog, Nodi Dehvari, Jessica M. Olsen, Alice Åslund, Gert Schaart, Elisabete Forsberg, Anna L. Sandström, Evelyn Zacharewicz, Sten M M van Beek, Roger Berlin, Mia Rinde
Publikováno v:
Diabetologia
Diabetologia, 63(8), 1603-1615. Springer, Cham
Diabetologia, 63(8), 1603-1615. Springer, Cham
Aims/hypothesis Chronic stimulation of β2-adrenoceptors, opposite to acute treatment, was reported to reduce blood glucose levels, as well as to improve glucose and insulin tolerance in rodent models of diabetes by essentially unknown mechanisms. We
Autor:
Mohsen Pakzad, Dana S. Hutchinson, Jon Merlin, Masaaki Sato, Tore Bengtsson, Cameron J. Nowell, Roger J. Summers, Richard Fahey, Bronwyn A Evans, Ling Yeong Chia
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
The recruitment of brite (or beige) adipocytes has been advocated as a means to combat obesity, due to their ability to phenotypically resemble brown adipocytes (BA). Lineage studies indicate that brite adipocytes are formed by differentiation of pre
Publikováno v:
Diabetologia. 50:158-167
In skeletal muscle, the storage of glycogen by insulin is regulated by glycogen synthase, which is regulated by glycogen synthase kinase 3 (GSK3). Here we examined whether adrenergic receptor activation, which can increase glucose uptake, regulates g
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 373:158-168
The present study investigates the action of zinterol at beta(3)-adrenoceptors. We used mouse primary brown adipocytes and Chinese hamster ovary (CHO-K1) cells expressing the mouse or human beta(3)-adrenoceptor. Zinterol was a full agonist at increas
Publikováno v:
British Journal of Pharmacology. 147:446-454
1. Beta-adrenoceptor (AR) agonists increase 2-deoxy-[3H]-D-glucose uptake (GU) via beta2-AR in rat L6 cells. The beta-AR agonists, zinterol (beta2-AR) and (-)-isoprenaline, increased cAMP accumulation in a concentration-dependent manner (pEC50=9.1+/-
Autor:
Dana S. Hutchinson, Tore Bengtsson
Publikováno v:
Endocrinology. 146:901-912
The role of α1-adrenoceptor activation on glucose uptake in L6 cells was investigated. The α1-adrenoceptor agonist phenylephrine [pEC50 (−log10 EC50), 5.27 ± 0.30] or cirazoline (pEC50, 5.00 ± 0.23) increased glucose uptake in a concentration-d
Publikováno v:
Endocrinology. 145:269-280
To identify the signaling pathways that mediate the adrenergic stimulation of glucose uptake in brown adipose tissue, we used mouse brown adipocytes in culture. The endogenous adrenergic neurotransmitter norepinephrine (NE) induced 2-deoxy-D-glucose
Publikováno v:
British Journal of Pharmacology. 137:9-18
1. The receptor that mediates the increase in glucose transport (GT) in response to beta-adrenoceptor (beta-AR) agonists was characterized in the rat skeletal muscle cell line L6, using the 2-deoxy-[(3)H]-D-glucose assay. 2. The beta(3)-AR agonist BR
Publikováno v:
British Journal of Pharmacology. 135:1903-1914
1. This study characterizes the mouse beta(3a)-adrenoceptor (AR) and the splice variant of the beta(3)-AR (beta(3b)-AR) expressed in Chinese hamster ovary cells (CHO-K1). 2. Stable clones with high (approximately 1200), medium (approximately 500) or
Autor:
Alfonso E. Garcia-Bennett, Tore Bengtsson, Natalia Kupferschmidt, Lluis Ballell, Robert I. Csikasz
Publikováno v:
Nanomedicine (London, England). 9(9)
Background: There is a need for medical treatments to curb the rising rate of obesity. Weight reduction is correlated with a decrease in associated risk factors and cholesterol levels in humans. Amorphous silica particles have been found to exert a h