Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Timo K. van den Berg"'
Autor:
Sander Engels, Katka Franke, Timo K. van den Berg, Anja J. de Jong, Muhammet F. Gulen, Monika C. Wolkers, Edith M. Janssen, Andrea Ablasser, Melania Balzarolo, Bas van Steensel
Publikováno v:
Open Biology, Vol 11, Iss 3 (2021)
Open biology, 11(3):210030. Royal Society Publishing
Open Biology
Open biology, 11(3):210030. Royal Society Publishing
Open Biology
Nucleic acid sensing through pattern recognition receptors is critical for immune recognition of microbial infections. Microbial DNA is frequently methylated at the N 6 position of adenines (m6A), a modification that is rare in mammalian host DNA. We
Autor:
Bas van Steensel, Katka Franke, Melania Balzarolo, Edith M. Janssen, Timo K. van den Berg, Anja J. de Jong, Sander Engels, Monika C. Wolkers
Nucleic acid sensing through pattern recognition receptors is critical for immune recognition of microbial infections. Microbial DNA is frequently methylated at the N6 position of adenines (m6A), a modification that is rare in mammalian host DNA. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6074a38afb74a54b5bdfbe1729ed0939
Autor:
Carolien A. M. Koeleman, Wim J E van Esch, Marcella de Boer, Taco W. Kuijpers, Manfred Wuhrer, Suzanne N. Lissenberg-Thunnissen, Rosina Plomp, Hanke L. Matlung, Juk Yee Mok, Mieke C. Brouwer, Theo Rispens, Remco Visser, Gestur Vidarsson, Louise W. Treffers, Arthur E. H. Bentlage, Timo K. van den Berg, Diana Wouters, Gillian Dekkers
Publikováno v:
Frontiers in Immunology, 8
Frontiers in immunology, 8. Frontiers Media S.A.
Frontiers in Immunology, Vol 8 (2017)
Frontiers in Immunology
Frontiers in immunology, 8. Frontiers Media S.A.
Frontiers in Immunology, Vol 8 (2017)
Frontiers in Immunology
Glycosylation of the immunoglobulin G (IgG)-Fc tail is required for binding to Fc-gamma receptors (FcγRs) and complement-component C1q. A variety of IgG1-glycoforms is detected in human sera. Several groups have found global or antigen-specific skew
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e66a2d915ab552de4c5a62fdb22a029
http://hdl.handle.net/1887/114803
http://hdl.handle.net/1887/114803
Autor:
Manfred Wuhrer, Suzanne N. Lissenberg-Thunnissen, Christine W. Bruggeman, Gestur Vidarsson, Louise W. Treffers, Sietse Q. Nagelkerke, Theo Rispens, Arthur E. H. Bentlage, Timo K. van den Berg, Gillian Dekkers, Taco W. Kuijpers, Carolien A. M. Koeleman
Publikováno v:
Journal of immunology (Baltimore, Md., 199(1), 204-211. American Association of Immunologists
Bruggeman, C W, Dekkers, G, Bentlage, A E H, Treffers, L W, Nagelkerke, S Q, Lissenberg-Thunnissen, S, Koeleman, C A M, Wuhrer, M, van den Berg, T K, Rispens, T, Vidarsson, G & Kuijpers, T W 2017, ' Enhanced Effector Functions Due to Antibody Defucosylation Depend on the Effector Cell Fcγ Receptor Profile ', Journal of Immunology, vol. 199, no. 1, pp. 204-211 . https://doi.org/10.4049/jimmunol.1700116
Journal of Immunology, 199(1), 204-211. American Association of Immunologists
Journal of Immunology, 199(1), 204-211
Bruggeman, C W, Dekkers, G, Bentlage, A E H, Treffers, L W, Nagelkerke, S Q, Lissenberg-Thunnissen, S, Koeleman, C A M, Wuhrer, M, van den Berg, T K, Rispens, T, Vidarsson, G & Kuijpers, T W 2017, ' Enhanced Effector Functions Due to Antibody Defucosylation Depend on the Effector Cell Fcγ Receptor Profile ', Journal of Immunology, vol. 199, no. 1, pp. 204-211 . https://doi.org/10.4049/jimmunol.1700116
Journal of Immunology, 199(1), 204-211. American Association of Immunologists
Journal of Immunology, 199(1), 204-211
Abs of the IgG isotype are glycosylated in their Fc domain at a conserved asparagine at position 297. Removal of the core fucose of this glycan greatly increases the affinity for FcγRIII, resulting in enhanced FcγRIII-mediated effector functions. N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b47bcccf99c2e634625077d63554f1
https://pure.amc.nl/en/publications/enhanced-effector-functions-due-to-antibody-defucosylation-depend-on-the-effector-cell-fc-receptor-profile(42124375-c194-410c-8f31-02dfaa46076f).html
https://pure.amc.nl/en/publications/enhanced-effector-functions-due-to-antibody-defucosylation-depend-on-the-effector-cell-fc-receptor-profile(42124375-c194-410c-8f31-02dfaa46076f).html
Autor:
Frank L. van de Veerdonk, Dirk Roos, Paul Verkuijlen, Anton T.J. Tool, Michel van Houdt, Martin Herbst, Johannes G. Liese, Taco W. Kuijpers, John L. van Hamme, Timo K. van den Berg, Roel P. Gazendam
Publikováno v:
Blood, 124(4), 590-7. American Society of Hematology
Blood, 124(4), 590-597. American Society of Hematology
Gazendam, R P, van Hamme, J L, Tool, A T J, van Houdt, M, Verkuijlen, P J J H, Herbst, M, Liese, J G, van de Veerdonk, F L, Roos, D, van den Berg, T K & Kuijpers, T W 2014, ' Two independent killing mechanisms of Candida albicans by human neutrophils : evidence from innate immunity defects ', Blood, vol. 124, no. 4, pp. 590-7 . https://doi.org/10.1182/blood-2014-01-551473
Blood, 124(4), 590-597. American Society of Hematology
Gazendam, R P, van Hamme, J L, Tool, A T J, van Houdt, M, Verkuijlen, P J J H, Herbst, M, Liese, J G, van de Veerdonk, F L, Roos, D, van den Berg, T K & Kuijpers, T W 2014, ' Two independent killing mechanisms of Candida albicans by human neutrophils : evidence from innate immunity defects ', Blood, vol. 124, no. 4, pp. 590-7 . https://doi.org/10.1182/blood-2014-01-551473
Invasive fungal infections, accompanied by high rates of mortality, represent an increasing problem in medicine. Neutrophils are the major effector immune cells in fungal killing. Based on studies with neutrophils from patients with defined genetic d
Autor:
Anton T.J. Tool, Judy Geissler, Timo K. van den Berg, Agata Drewniak, Taco W. Kuijpers, Robin van Bruggen
Publikováno v:
Blood, 115(22), 4588-96. American Society of Hematology
Drewniak, A, Tool, A T J, Geissler, J, van Bruggen, R, van den Berg, T K & Kuijpers, T W 2010, ' Toll-like receptor-induced reactivity and strongly potentiated IL-8 production in granulocytes mobilized for transfusion purposes ', Blood, vol. 115, no. 22, pp. 4588-96 . https://doi.org/10.1182/blood-2009-11-253245
Blood, 115(22), 4588-4596. American Society of Hematology
Drewniak, A, Tool, A T J, Geissler, J, van Bruggen, R, van den Berg, T K & Kuijpers, T W 2010, ' Toll-like receptor-induced reactivity and strongly potentiated IL-8 production in granulocytes mobilized for transfusion purposes ', Blood, vol. 115, no. 22, pp. 4588-96 . https://doi.org/10.1182/blood-2009-11-253245
Blood, 115(22), 4588-4596. American Society of Hematology
Transfusion of granulocytes from granulocyte-colony stimulating factor (G-CSF)/dexamethasone (dexa)–treated donors can be beneficial for neutropenic recipients that are refractory to antimicrobial therapy. G-CSF/dexa treatment not only increases th
Publikováno v:
Irandoust, M, van den Berg, T K, Kaspers, G J L & Cloos, J 2009, ' Role of Tyrosine Phosphatase Inhibitors in Cancer Treatment with Emphasis on SH2 Domain-Containing Tyrosine Phosphatases (SHPs) ', Anti-Cancer Agents in Medicinal Chemistry, vol. 9, no. 2, pp. 212-220 . https://doi.org/10.2174/187152009787313864
Irandoust, M, van den Berg, T K, Kaspers, G J L & Cloos, J 2009, ' Role of tyrosine phosphatase inhibitors in cancer treatment with emphasis on SH2 domain-containing tyrosine phosphatases (SHPs) ', Anti-Cancer Agents in Medicinal Chemistry, vol. 9, no. 2, pp. 212-20 .
Anti-Cancer Agents in Medicinal Chemistry, 9(2), 212-220. Bentham Science Publishers B.V.
Irandoust, M, van den Berg, T K, Kaspers, G J L & Cloos, J 2009, ' Role of tyrosine phosphatase inhibitors in cancer treatment with emphasis on SH2 domain-containing tyrosine phosphatases (SHPs) ', Anti-Cancer Agents in Medicinal Chemistry, vol. 9, no. 2, pp. 212-20 .
Anti-Cancer Agents in Medicinal Chemistry, 9(2), 212-220. Bentham Science Publishers B.V.
Protein tyrosine phosphorylation is one of the key mechanisms involved in signal transduction pathways. This modification is regulated by concerted action of protein tyrosine phosphatases and protein tyrosine kinases. Deregulation of either of these
Autor:
Jacqueline Alblas, Christine D. Dijkstra, Chantal Renardel de Lavalette, Timo K. van den Berg, Marion H. Brown, Henk Honing
Publikováno v:
Alblas, J, Honing, H, de Lavalette, C R, Brown, M H, Dijkstra, C D & van den Berg, T K 2005, ' Signal regulatory protein alpha ligation induces macrophage nitric oxide production through JAK/STAT-and phosphatidylinositol 3-kinase/Rac1/NAPDH oxidase/H2O2-dependent pathways ', Molecular and Cellular Biology, vol. 25, no. 16, pp. 7181-7192 . https://doi.org/10.1128/MCB.25.16.7181-7192.2005
Molecular and Cellular Biology, 25(16), 7181-7192
Molecular and cellular biology, 25(16), 7181-7192. American Society for Microbiology
Molecular and Cellular Biology, 25(16), 7181-7192
Molecular and cellular biology, 25(16), 7181-7192. American Society for Microbiology
Signal regulatory protein alpha (SIRPalpha) is a glycoprotein receptor that recruits and signals via the tyrosine phosphatases SHP-1 and SHP-2. In macrophages SIRPalpha can negatively regulate the phagocytosis of host cells and the production of tumo
Autor:
Timo K. van den Berg, Véronique Gomord, Irma van Die, Frans N. J. Kooyman, Lonneke Vervelde, Richard D. Cummings
Publikováno v:
FEBS Letters, 463(1-2), 189-93. Wiley-Blackwell
FEBS letters, 463(1-2), 189-193. Wiley-Blackwell
FEBS letters, 463(1-2), 189-193. Wiley-Blackwell
Synthesis of parasite specific IgE plays a critical role in the defence against helminth infections. We report here that IgE from serum from Schistosoma mansoni infected mice and Haemonchus contortus infected sheep recognizes complex-type N-glycans f
Autor:
Christine D. Dijkstra, Helga E. de Vries, Timo K. van den Berg, Sarah Floris, Annemarie Ledeboer, John G.J.M. Bol, F. J. H. Tilders, Anne-Marie van Dam, Chantal Renardel de Lavalette, Anne Wierinckx
Publikováno v:
Ledeboer, A, Wierinckx, A, Bol, J G J M, Floris, S, Renardel de Lavalette, C, De Vries, H E, van den Berg, T K, Dijkstra, C D, Tilders, F J H & van dam, A-M 2003, ' Regional and temporal expression patterns of interleukin-10, interleukin-10 receptor and adhesion molecules in the rat spinal cord during chronic relapsing EAE ', Journal of Neuroimmunology, vol. 136, no. 1-2, pp. 94-103 .
Journal of Neuroimmunology, 136(1-2), 94-103. Elsevier
Journal of neuroimmunology, 136(1-2), 94-103. Elsevier
Journal of Neuroimmunology, 136(1-2), 94-103. Elsevier
Journal of neuroimmunology, 136(1-2), 94-103. Elsevier
Adhesion molecules intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) mediate leukocyte infiltration into the CNS, in experimental autoimmune encephalomyelitis (EAE) and multiple sclerosis (MS). Because exogenou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::979fa41267ffc11f505f833378d140d5
https://research.vumc.nl/en/publications/b25719ef-4a26-4638-9f18-eb578c75175e
https://research.vumc.nl/en/publications/b25719ef-4a26-4638-9f18-eb578c75175e