Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Ryo, Ito"'
Autor:
Mai Mochizuki, Sadafumi Kawamura, Kazuto Matsuura, Keiichi Tamai, Takayuki Imai, Wataru Iwai, Jun Yasuda, Akira Sugawara, Yukinori Asada, Makoto Abue, Tomoko Yamazaki, Haruna Fujimori, Rie Shibuya-Takahashi, Satoshi Saijoh, Ryo Ito, Yukio Katori, Mao Nakamura-Shima, Kazuo Sugamura, Kazunori Yamaguchi, Yu Katayose, Yuta Wakui, Kennichi Satoh
Publikováno v:
Biochemical and Biophysical Research Communications. 537:132-139
Cancer stem cells (CSCs) are believed to cause cancer metastasis and recurrence. BEX2 (brain expressed X-linked gene 2) is a CSC-related gene that is expressed in dormant CSCs in cholangiocarcinoma and induces resistance against chemotherapy. The aim
Publikováno v:
Biochemical and Biophysical Research Communications. 534:672-679
Aldosterone is synthesized in the adrenal by the aldosterone synthase CYP11B2. Although the control of CYP11B2 expression is important to maintain the mineral homeostasis, its overexpression induced by the depolarization-induced calcium (Ca2+) signal
Autor:
Ryo Ito, Yoshitomi Yayoi, Koji Watanabe, Teruki Hamada, Yasuhiro Hirata, Yasufumi Miyamoto, Seiji Miwatashi, Nobuyuki Takakura, Kazuaki Takami, Yoshihiko Hirozane, Naoyoshi Noguchi, Yusuke Moritoh, Mitsugi Ookawara, Hideki Furukawa, Jumpei Aida, Masanori Watanabe, Hitomi Yuko, Tsuyoshi Maekawa
Publikováno v:
Journal of Medicinal Chemistry. 63:10352-10379
GPR40/FFAR1 is a G-protein-coupled receptor expressed in pancreatic β-cells and enteroendocrine cells. GPR40 activation stimulates secretions of insulin and incretin, both of which are the pivotal regulators of glycemic control. Therefore, a GPR40 a
FABP7 Regulates Acetyl-CoA Metabolism Through the Interaction with ACLY in the Nucleus of Astrocytes
Autor:
Yuji Owada, Masayuki Kanamori, Kosuke Jozaki, Shuhei Kobayashi, Subrata Kumar Shil, Ryo Zama, Hiroshi Kogo, Ariful Islam, Kazuhiko Igarashi, Hirofumi Miyazaki, Chie Shimamoto-Mitsuyama, Yoshiteru Kagawa, Shin Ichiro Kanno, Banlanjo Abdulaziz Umaru, Shun Sato, Ryo Ito, Teiji Tominaga, Hiroki Shima, Akira Yasui, Kohji Fukunaga, Yui Yamamoto, Takeo Yoshikawa, Norihiro Sugino, Akira Sugawara
Publikováno v:
Molecular Neurobiology
Fatty acid binding protein 7 (FABP7) is an intracellular fatty acid chaperon that is highly expressed in astrocytes, oligodendrocyte-precursor cells, and malignant glioma. Previously, we reported that FABP7 regulates the response to extracellular sti
Autor:
Takayuki Anazawa, Nobuya Inagaki, Junji Fujikura, Masahito Ogura, Hideaki Okajima, Ryo Ito, Toshihiro Nakamura, Shinji Uemoto
Publikováno v:
Journal of Diabetes Investigation, Vol 11, Iss 2, Pp 363-372 (2020)
Journal of Diabetes Investigation
Journal of Diabetes Investigation
Aims/Introduction To investigate the long‐term efficacy and safety of islet transplantation (ITx) compared with multiple daily injections (MDI) or continuous subcutaneous insulin infusion (CSII). Materials and Methods Among 619 patients diagnosed a
Autor:
Hiroki Shima, Ikuko Sato, Kazuhiko Igarashi, Koji Masuda, Akira Sugawara, Ryo Ito, Katsuhiko Shirahige, Hiroki Shimada, Atsushi Yokoyama
Publikováno v:
Endocrine journal. 68(4)
Angiotensin II (Ang II) is a well-known peptide that maintains the balance of electrolytes in the higher vertebrates. Ang II stimulation in the adrenal gland induces the synthesis of mineralocorticoids, mainly aldosterone, through the up-regulation o
Autor:
Shota Suzuki, Saki Izumi, Ken-ichi Nunoya, Takafumi Komori, Ryo Ito, Haruo Imawaka, Hidetaka Akita, Kenta Umehara, Keita Kitamura, Tomomi Furihata, Naomi Wakayama, Naohiko Anzai, Yoshiyuki Yamaura
Publikováno v:
Molecular pharmaceutics. 16(11)
Brain microvascular endothelial cells (BMEC), together with astrocytes and pericytes, form the blood-brain barrier (BBB) that strictly restricts drug penetration into the brain. Therefore, in central nervous system drug development, the establishment
Publikováno v:
Chemical Communications. 54:7609-7612
An oxidation system in which iodic acid (HIO3) is used as an oxidant in the presence of N-hydroxyphthalimide (NHPI) permitted the selective hydroxylation of tertiary C-H bonds and the lactonization of carboxylic acids containing a tertiary carbon cen
Publikováno v:
Biochemical and Biophysical Research Communications. 489:21-28
CYP11B2 is a key enzyme involved in the synthesis of the mineralocorticoid aldosterone. CYP11B2 expression in the adrenal glands is controlled by the renin-angiotensin system (RAS), and plays an important role in the maintenance of electrolyte metabo
Autor:
Kenji Takahashi, Ryohei Kakuchi, Kazuaki Ninomiya, Hadi Abroshan, Hyung J. Kim, Shuhei Nomura, Ryo Ito, Tomoyuki Ikai, Katsuhiro Maeda
Publikováno v:
RSC Advances. 7:9423-9430
Detailed insights into the organocatalytic properties of imidazolium-based ionic liquids (Im-ILs) for transesterification of cellulose with isopropenyl acetate (IPA) are presented. According to model transesterification reactions and their computatio