Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Quansheng Zhou"'
Autor:
Zhe Zhao, Shufen Xiang, Bin Zhang, Chunping Lv, Zihe Huo, Zhifei Cao, Mei Meng, Gaochuan Zhang, Quansheng Zhou, Liang Dong, Lan Yang, Bo Yang, Pan Zhang, Shucheng Shi, Xingdong Xu
Publikováno v:
Cell Death Differ
Cancer cells are defective in DNA repair, so they experience increased DNA strand breaks, genome instability, gene mutagenesis, and tumorigenicity; however, multiple classic DNA repair genes and pathways are strongly activated in malignant tumor cell
Autor:
Jindan Qi, Shufen Xiang, Tong Zhang, Quansheng Zhou, Mengli Zhang, Yijun Wei, Mei Meng, Jun Yao, Xiaohua Wang, Zhe Zhao
Publikováno v:
Cell Death and Disease, Vol 11, Iss 5, Pp 1-14 (2020)
Cell Death & Disease
Cell Death & Disease
Salvador homolog-1 (SAV1) is a tumor suppressor required for activation of the tumor-suppressive Hippo pathway and inhibition of tumorigenesis. SAV1 is defective in several cancer types. SAV1 deficiency in cells promotes tumorigenesis and cancer meta
Publikováno v:
Toxicology and applied pharmacology. 388
Gastric cancer ranks as the third leading cause of cancer-related death worldwide. The uncontrolled tumor growth and robust metastasis are key factors to cause the cancer patient death. Mechanistically, aberrant activation of Notch and NF-κB signali
Publikováno v:
Journal of cellular physiology. 234(7)
Metastatic melanoma accounts for 60% of death for skin cancer. Although great efforts have been made to treat the disease, effective drugs against metastatic melanoma still lack at the clinical setting. In the current study, we found that lycorine, a
Publikováno v:
Science China. Chemistry
Lycorine is the major active component from the amaryllidaceae family plant Lycoris radiate, a represent traditional Chinese medicinal herb, and is one of the typical alkaloids with pyrrolophenanthridine nucleus core. Lycorine has drawn great interes
Autor:
Wu-Zhong Shen, Peter J. Sims, Zhen-Gang Peng, Xi Li, Guo-Qiang Chen, Ke-Wen Zhao, Dong Li, Zhu Chen, Qian Zhao, Therese Wiedmer, Quansheng Zhou, Ji Zhao, Ying Huang
Publikováno v:
Blood. 104:3731-3738
Although phospholipid scramblase 1 (PLSCR1) was originally identified based on its capacity to promote transbilayer movement of membrane phospholipids, subsequent studies also provided evidence for its role in cell proliferation, maturation, and apop
Autor:
Ji Zhao, Aimin Zhou, Peter J. Sims, Robert H. Silverman, Jeanna Guenther, Roger Slee, Beihua Dong, Ronald N. Harty, Amiya K. Banerjee, Santanu Bose, Therese Wiedmer, Bryan R.G. Williams, Quansheng Zhou
Publikováno v:
Journal of Virology. 78:8983-8993
Interferons (IFNs) are the principal cytokines responsible for mediating innate immunity against viral infections (7). How IFNs establish an antiviral state in cells has been a subject of investigation since their discovery (21). Nevertheless, mechan
Autor:
Shilong Fu, Gaochuan Zhang, Quansheng Zhou, Di Yu, Wenming Liu, Meimei Bao, Zhifei Cao, Yanyan Pan
Publikováno v:
Toxicology letters. 226(3)
Uncontrolled cell proliferation and robust angiogenesis play critical roles in osteosarcoma growth and metastasis. In this study we explored novel agents derived from traditional Chinese medicinal herbs that potently inhibit osteosarcoma growth and m
Autor:
Robert H. Silverman, Fahad Al-Zoghaibi, Ji Zhao, Quansheng Zhou, Therese Wiedmer, Aimin Zhou, Peter J. Sims
Publikováno v:
Blood. 95:2593-2599
Interferons (IFNs) mediate their diverse biologic activities through induction of the expression of multiple genes. Whereas the mode of action of certain of these IFN-regulated genes has been well characterized, most of the molecular and cellular eve
Publikováno v:
Blood. 92:1707-1712
Scott syndrome is a rare inherited bleeding disorder in which platelets and other blood cells fail to promote normal assembly of the membrane-stabilized proteases of the plasma coagulation system. The defect in Scott blood cells is known to reflect i