Zobrazeno 1 - 10
of 209
pro vyhledávání: '"Paul J. Nestel"'
Autor:
Graeme I. Lancaster, Denis Sviridov, Nigora Mukhamedova, Takahiro Kameda, Gerard Pernes, Peter J. Meikle, Ryunosuke Ohkawa, Boris L. Vaisman, Andrew J. Murphy, Ayuko Hara, Ying Fu, Michael Ditiatkovski, Shao-Jui Lai, Paul J. Nestel, Alan T. Remaley, Hann Low, Dmitri Sviridov, Minoru Tozuka, Yuna Horiuchi, Mai Sasaoka, Azusa Yamazaki
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 12, Pp 1577-1588 (2020)
J Lipid Res
J Lipid Res
Lipoproteins play a key role in transport of cholesterol to and from tissues. Recent studies have also demonstrated that red blood cells (RBCs), which carry large quantities of free cholesterol in their membrane, play an important role in reverse cho
Autor:
Adam Alexander T. Smith, Man K.S. Lee, Michelle Cinel, Bronwyn A. Kingwell, Sudip Paul, Paul J. Nestel, Kevin Culham, Natalie A. Mellett, Kaushala S. Jayawardana, Kevin A. Gunawan, Peter J. Meikle, Jacqueline M. Weir, Graeme I. Lancaster, Andrew J. Murphy
Publikováno v:
Journal of Lipid Research
Journal of Lipid Research, Vol 62, Iss, Pp 100092-(2021)
Journal of Lipid Research, Vol 62, Iss, Pp 100092-(2021)
Plasmalogens are membrane glycerophospholipids with diverse biological functions. Reduced plasmalogen levels have been observed in metabolic diseases; hence, increasing their levels might be beneficial in ameliorating these conditions. Shark liver oi
Autor:
Terje R. Pedersen, Gregory G. Schwartz, Andrew Tonkin, Anastasia Lesogor, Helen M. Colhoun, Christiane Drechsler, Florian Kronenberg, Peter Willeit, John Simes, Paul M. Ridker, Sotirios Tsimikas, Anders G. Olsson, Samia Mora, Paul J. Nestel, Christoph Wanner
Publikováno v:
Willeit, P, Ridker, P M, Nestel, P J, Simes, J, Tonkin, A M, Pedersen, T R, Schwartz, G G, Olsson, A G, Colhoun, H M, Kronenberg, F, Drechsler, C, Wanner, C, Mora, S, Lesogor, A & Tsimikas, S 2018, ' Baseline and on-statin treatment lipoprotein(a) levels for prediction of cardiovascular events : individual patient-data meta-analysis of statin outcome trials ', The Lancet, vol. 392, no. 10155, pp. 1311-1320 . https://doi.org/10.1016/S0140-6736(18)31652-0
BACKGROUND: Elevated lipoprotein(a) is a genetic risk factor for cardiovascular disease in general population studies. However, its contribution to risk for cardiovascular events in patients with established cardiovascular disease or on statin therap
Autor:
Anmar A. Khan, Nora E. Straznicky, Gavin W. Lambert, Piyushkumar A. Mundra, Gerard Wong, Theodore W.K. Ng, Zahir H Alshehry, Paul J. Nestel, Ricardo Tan, Christopher K. Barlow, Natalie A. Mellett, Peter J. Meikle, Bronwyn A. Kingwell, Kevin Huynh, Jacquelyn M. Weir
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38:438-447
Objective— High-density lipoprotein (HDL) lipid composition and function may better reflect cardiovascular risk than HDL cholesterol concentration. This study characterized the relationships between HDL composition, metabolism, and function in meta
Autor:
Nora E. Straznicky, Piyushkumar A. Mundra, Kaushala S. Jayawardana, Gavin W. Lambert, Anmar A. Khan, Paul J. Nestel, Natalie A. Mellett, Peter J. Meikle
Publikováno v:
Atherosclerosis. 256:21-28
Background and aims Plasma sphingolipids including ceramides, and gangliosides are associated with insulin resistance (IR) through effects on insulin signalling and glucose metabolism. Our studies of subjects with metabolic syndrome (MetS) showed clo
Autor:
Zahir H Alshehry, Graham S. Hillis, Kaushala S. Jayawardana, Piyushkumar A. Mundra, Christopher K. Barlow, Sophia Zoungas, Natalie A. Mellett, Paul J. Nestel, Malcolm J. McConville, Elizabeth H Barnes, John Simes, Bronwyn A. Kingwell, Andrew Tonkin, David R. Sullivan, Kevin Huynh, Ian C. Marschner, Peter J. Meikle, Corey Giles, Gerard Wong, Adrienne Kirby, Peter L. Thompson, Mark Woodward, John Chalmers
Publikováno v:
JCI Insight. 4
BACKGROUND: Statins have pleiotropic effects on lipid metabolism. The relationship between these effects and future cardiovascular events is unknown. We characterized the changes in lipids upon pravastatin treatment and defined the relationship with
Autor:
Paul J. Nestel
Publikováno v:
Current hypertension reports. 21(2)
Do dietary fats lower blood pressure? This review covers total fats, individual fatty acids and foods that provide specific fats. Evidence for blood pressure lowering is stronger for supplements providing individual marine fatty acids than for fish i
Autor:
Lesley Cheng, Jennifer F Hoy, Tatiana Pushkarsky, Larisa Dubrovsky, Nigora Mukhamedova, Michael Bukrinsky, Dmitri Sviridov, Andrew F. Hill, Maria Silvana Di Yacovo, Elizabeth M Dewar, Gary L. Simon, Anthony M. Dart, Paul J. Nestel, Maria Saumoy, Catherine Downs, Anh Hoang, Hann Low, Michael L. Fitzgerald
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215620 (2019)
HIV infection is known to be associated with cardiometabolic abnormalities; here we investigated the progression and causes of these abnormalities. Three groups of participants were recruited: HIV-negative subjects and two groups of treatment-naive H
Autor:
David Espinoza, Wendy Hague, John Elliott, Andrew Tonkin, Anthony C Keech, Ralph A.H. Stewart, Kristy P. Robledo, Lipid Study Investigators, Paul Glasziou, Harvey D. White, David R. Sullivan, Paul J. Nestel, Stefan Blankenberg, John Simes, Tanja Zeller
Publikováno v:
Circulation. 138(7)
Background: D-dimer, a degradation product of cross-linked fibrin, is a marker for hypercoagulability and thrombotic events. Moderately elevated levels of D-dimer are associated with the risk of venous and arterial events in patients with vascular di
Autor:
Lipid Study Investigators, Paul J. Nestel, Kristy Mann, Stefan Blankenberg, David Colquhoun, David Hunt, David R. Sullivan, John Simes, Ralph A.H. Stewart, Andrew Tonkin, Anthony C Keech, Peter L. Thompson, Malcolm J. West, Harvey D. White
Publikováno v:
Journal of the American College of Cardiology. 63(4):345-354
Objectives This study sought to assess whether baseline and change in contemporary sensitive troponin I (TnI) levels predicts coronary heart disease (CHD) death and myocardial infarction (MI), and to determine the effects of pravastatin on TnI levels