Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Michael Lee"'
Autor:
Cédric Diot, Aurian P. García-González, Andre F. Vieira, Melissa Walker, Megan Honeywell, Hailey Doyle, Olga Ponomarova, Yomari Rivera, Huimin Na, Hefei Zhang, Michael Lee, Carissa P. Olsen, Albertha J.M. Walhout
Publikováno v:
Nature communications. 13(1)
Tamoxifen is a selective estrogen receptor (ER) modulator that is used to treat ER-positive breast cancer, but that at high doses kills both ER-positive and ER-negative breast cancer cells. We recapitulate this off-target effect in Caenorhabditis ele
Publikováno v:
The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology
Autophagy regulators are often effective as potential cancer therapeutic agents. Here, we investigated paclitaxel sensitivity in cells with knockout (KO) of ATG5 gene. The ATG5 KO in multidrug resistant v-Ha-ras-transformed NIH 3T3 cells (Ras-NIH 3T3
Autor:
Sung-Hee Hwang, Michael Lee
Publikováno v:
Animal Cells and Systems
Animal Cells and Systems, Vol 24, Iss 1, Pp 17-25 (2020)
Animal Cells and Systems, Vol 24, Iss 1, Pp 17-25 (2020)
Several studies have revealed the functional importance of autophagy in both adipogenesis and carcinogenesis. Here, we investigated autophagy as a link between tumorigenesis and adipogenesis using 3T3-L1 cells, which have been shown to closely mimic
Publikováno v:
Biochemical and Biophysical Research Communications. 513:234-241
Autophagy plays a contradictory role in cell survival and death. Here, we investigated changes in paclitaxel sensitivity of cells with an ATG5 gene-knockout (KO), incapable of synthesizing an E3 ubiquitin ligase necessary for autophagy. The ATG5 KO i
Autor:
Samuel P. Veres, J. Michael Lee
Publikováno v:
Journal of Applied Physiology. 126:832-841
Advanced glycation end-products (AGEs) are formed in vivo from the nonenzymatic reaction between sugars and proteins. AGEs accumulate in long-lived tissues like tendons, cross-linking neighboring collagen molecules, and are in part complicit in conne
Publikováno v:
International Biodeterioration & Biodegradation. 137:153-157
This study evaluated the termite susceptibility of Papua New Guinea (PNG) balsa (Ochroma pyramidale) against Australia's most economically important wood-destroying termite species, Coptotermes acinaciformis. Samples of envelope treated PNG balsa wit
Autor:
Christopher Ré, Tsung-Lu Michael Lee, Samuel C. Kou, Kun-Hsing Yu, Michael Snyder, Yu-Ju Chen, Isaac S. Kohane, Jung-Hsien Chiang
Publikováno v:
Journal of Proteome Research. 17:4345-4357
Targeted metabolomics and biochemical studies complement the ongoing investigations led by the Human Proteome Organization (HUPO) Biology/Disease-driven-Human Proteome Project (B/D-HPP). However, it is challenging to identify and prioritize metabolit
Publikováno v:
Indonesian Food Science & Technology Journal; Vol. 3 No. 2 (2020): Vol 3 No 2, July 2020; 34-37
— A method consist of co-crystallization, agglomeration, drying has been applied to develop a powder drink from butterfly pea flower (Clitoria ternatea) extract. The butterfly pea flower extract was concentrated by vacuum evaporation and incorporat
Autor:
Alexander P. Sobinoff, Michael Lee, Joshua A. M. Allen, Tatjana Kilo, Hilda A. Pickett, Raja S. Vasireddy, Christopher B. Nelson, Vivian Francília Silva Kahl
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Telomeres are repetitive regions of DNA bound by specialized proteins at the termini of linear chromosomes that prevent the natural chromosome ends from being recognized as DNA double strand breaks. Telomeric DNA is gradually eroded with each round o
Autor:
Sumanta K. Pal, Maya Otto-Duessel, Michael Lee, Meghan Salgia, Ben T. Copeland, David K. Ann, Catherine C. Elix, Christopher Yoo, Jeremy O. Jones, Ben Yi Tew
Publikováno v:
Prostate
Background Prostate cancer (PC) remains a leading cause of cancer mortality and the most successful chemopreventative and treatment strategies for PC come from targeting the androgen receptor (AR). Although AR plays a key role, it is likely that othe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67bc7e64a8eeadf86757d61a294a2675
https://europepmc.org/articles/PMC8985763/
https://europepmc.org/articles/PMC8985763/