Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Lorna Rodriguez-Rodriguez"'
Autor:
Bhavna S. Paratala, Jon H. Chung, Casey B. Williams, Bahar Yilmazel, Whitney Petrosky, Kirstin Williams, Alexa B. Schrock, Laurie M. Gay, Ellen Lee, Sonia C. Dolfi, Kien Pham, Stephanie Lin, Ming Yao, Atul Kulkarni, Frances DiClemente, Chen Liu, Lorna Rodriguez-Rodriguez, Shridar Ganesan, Jeffrey S. Ross, Siraj M. Ali, Brian Leyland-Jones, Kim M. Hirshfield
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications
Nature Communications
Fusions involving the oncogenic gene RET have been observed in thyroid and lung cancers. Here we report RET gene alterations, including amplification, missense mutations, known fusions, novel fusions, and rearrangements in breast cancer. Their freque
Publikováno v:
Cancer Research. 81:2432-2432
Background: Signal transducer and activator of transcription 3 (STAT3) activation promotes tumor cell survival, immune evasion, metastasis, and drug resistance in PARP inhibitors and platinum-based chemotherapy. Objective: Based on our in-vitro findi
Autor:
Lorna Rodriguez-Rodriguez, Paula B. Caffrey, Muthu N. Kumaran, Mira Hellmann, Wilberto Nieves-Neira, Brian Buckley, Michael P. Kane, Murugesan Gounder, Darlene Gibbon, Gerald D. Frenkel, Mihae Song, Weichung Shih, Ami Vaidya
Publikováno v:
Gynecologic oncology. 150(3)
Purpose Preclinical studies performed in our laboratory have shown that high-dose selenium inhibits the development of carboplatin drug resistance in an ovarian cancer mouse xenograft model. Based on these data, as well as the potential serious toxic
Autor:
Lorna Rodriguez-Rodriguez, A. Buckley de Meritens, Aliza L. Leiser, Eugenia Girda, David L. Nelson, Ruth Stephenson
Publikováno v:
Gynecologic Oncology. 154:93
Autor:
Lorna Rodriguez-Rodriguez, Olena Taratula, Tamara Minko, Vatsal Shah, Olga B. Garbuzenko, Oleh Taratula
Publikováno v:
Clinical Cancer Research. 19:6193-6204
Purpose: The proposed project is aimed at enhancing the efficiency of epithelial ovarian cancer treatment and reducing adverse side effects of chemotherapy using nanotechnology. Overexpression of the CD44 membrane receptor results in tumor initiation
Autor:
Lorna Rodriguez-Rodriguez, Elisa V. Bandera, Valerie S. Lee, C. Bethan Powell, Lawrence H. Kushi
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 22(23)
Purpose: Among patients with ovarian cancer, African American (AA) women experience poorer survival compared with other race/ethnicity groups. This has been attributed to differences in access to health care. Experimental Design: We evaluated racial/
Autor:
Eugenia Girda, David L. Nelson, Lorna Rodriguez-Rodriguez, Malcolm Finlayson, Aliza L. Leiser, Ruth Stephenson, Alexandre Buckley de Meritens, Michael H. Silverman
Publikováno v:
Journal of Clinical Oncology. 36:TPS5608-TPS5608
TPS5608Background: Ovarian cancer often presents in advanced stages and is treated with platinum-based chemotherapy. However, many patients develop platinum-resistant disease with either failing to...
Autor:
Valerie S. Lee, Lawrence H. Kushi, Lorna Rodriguez-Rodriguez, C. Bethan Powell, Elisa V. Bandera
Publikováno v:
JAMA oncology. 1(6)
Optimal chemotherapy dosing in obese patients remains uncertain, with variation in practice. Dose reduction strategies are often used to avoid chemotoxicity, but recent American Society of Clinical Oncology guidelines recommend full dose.To evaluate
Autor:
Sara H. Olson, Elisa V. Bandera, Melony King, Lisa E. Paddock, Lorna Rodriguez-Rodriguez, Urmila Chandran
Publikováno v:
BMC Women's Health, Vol 11, Iss 1, p 40 (2011)
BMC Women's Health
BMC Women's Health
Background While there is extensive literature evaluating the impact of phytoestrogen consumption on breast cancer risk, its role on ovarian cancer has received little attention. Methods We conducted a population-based case-control study to evaluate
Publikováno v:
Gynecologic Oncology. 137:56