Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jeremy A. Leonard"'
Autor:
Miyoung Yoon, Rebecca A. Clewell, Chantel I. Nicolas, Jerry L. Campbell, Jeremy A. Leonard, Harvey J. Clewell, Alina Efremenko, Melvin E. Andersen, Yu-Mei Tan, Katherine Phillips, Patrick D. McMullen
Publikováno v:
Toxicol In Vitro
Advancements in measurement and modeling capabilities are providing unprecedented access to estimates of chemical exposure and bioactivity. With this influx of new data, there is a need for frameworks that help organize and disseminate information on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::860210bee5556db4f1820d5500e0bd42
https://europepmc.org/articles/PMC8204916/
https://europepmc.org/articles/PMC8204916/
Autor:
Shih Heng Chen, Mingri Guo, Shuo Li, Yueh Feng Sung, Chun Hsien Chu, Jau-Shyong Hong, Jeremy A. Leonard, Esteban A. Oyarzabal, Qingshan Wang, Ru Band Lu, Shiou Lan Chen, Yu Mei Tan
Publikováno v:
Molecular Neurobiology. 55:8001-8013
This study investigated the physiological regulation of brain immune homeostasis in rat primary neuron-glial cultures by sub-nanomolar concentrations of prostaglandin E2 (PGE(2)). We demonstrated that 0.01 to 10 nM PGE(2) protected dopaminergic neuro
Autor:
Marjory Moreau, Yu-Mei Tan, Martin B. Phillips, Katherine Phillips, Harvey J. Clewell, Sherrie Smith, Kristin Isaacs, Jeremy A. Leonard, Salil N. Pendse, Miyoung Yoon, Chantel I. Nicolas, Jerry L. Campbell, Harish Pudukodu
Publikováno v:
Chemosphere
A few different exposure prediction tools were evaluated for use in the new in vitro -based safety assessment paradigm using di-2-ethylhexyl phthalate (DEHP) and dibutyl phthalate (DnBP) as case compounds. Daily intake of each phthalate was estimated
Autor:
Jeremy A. Leonard, Hannah Pope-Varsalona, Anna Lowit, Yu-Mei Tan, Evisabel Craig, Mark D. Nelms, Monique M. Perron, Sarah Dobreniecki
Publikováno v:
Regulatory Toxicology and Pharmacology. 107:104419
In 2016, the United States Environmental Protection Agency's (EPA) Office of Pesticide Programs published guidelines for establishing candidate common mechanism groups (CMGs) for cumulative risk assessment (CRA) weight-of-evidence-based screenings. A
Autor:
J. Christopher Taylor, Emily K. Cira, Michael S. Wetz, Benjamin D. McGlaughon, Jeremy A. Leonard, David G. Kimmel, Hans W. Paerl
Publikováno v:
Estuarine, Coastal and Shelf Science. 157:59-68
Estuaries often have distinct zones of high chlorophyll a concentrations, known as chlorophyll maximum (CMAX). The persistence of these features is often attributed to physical (mixing and light availability) and chemical (nutrient availability) feat
Publikováno v:
Aquatic Microbial Ecology. 63:133-143
We assessed the role of top-down versus bottom-up factors in regulating picophyto- plankton (PicoP) growth and overall phytoplankton size structure in a eutrophic estuary. PicoP bio- mass reached an annual maximum in summer/fall and was positively co
Autor:
Jeremy A. Leonard, Jingtao Lu, Christopher M. Grulke, Martin B. Phillips, Miyoung Yoon, Kathleen J Brown, Robin McDougall, Yu-Mei Tan, Bruce Young, William Lefew
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 73(3)
Sources of uncertainty involved in exposure reconstruction for short half-life chemicals were characterized using computational models that link external exposures to biomarkers. Using carbaryl as an example, an exposure model, the Cumulative and Agg