Zobrazeno 1 - 10
of 59
pro vyhledávání: '"James Blanchard"'
Autor:
Andrew Robert Drews, Sandeep Tamrakar, Patrick James Blanchard, Yuxiang Wang, Tiffany R. Walsh, Alper Kiziltas
Publikováno v:
Biomacromolecules. 22(9)
The use of cellulose has considerable promise in a wide range of industrial applications but is hampered by degradation in mechanical properties due to ambient moisture uptake. Existing models of equilibrium moisture content can predict the impact of
Autor:
Isra Khatib, David Cipolla, Hak-Kim Chan, Dipesh Khanal, James Blanchard, Juanfang Ruan, Francis Dayton
Publikováno v:
International Journal of Pharmaceutics
This study was conducted to evaluate the feasibility of developing inhalable dry powders of liposomal encapsulated ciprofloxacin nanocrystals (LECN) for controlled drug release. Dry powders of LECN were produced by freeze-thaw followed by spray dryin
Autor:
Brooke Grasperge, James Blanchard, Jeffrey D. Lifson, Michael Benson, Nina Derby, José A. Fernández-Romero, Olga Mizenina, Walid Heneine, M. Melissa Peet, Zachary Lloyd, Aixa Rodriguez, Shweta R. Ugaonkar, Meropi Aravantinou, Agegnehu Gettie, Thomas M. Zydowsky, Patrick Barnable, Manshun Lai, Manjari Lal, Asa Wesenberg, Melissa Robbiani, Natalia Teleshova, Barry R. O'Keefe, Larisa Kizima, Elena Martinelli, Kyle R. Kleinbeck, Keith Levendosky
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Human immunodeficiency virus (HIV) pre-exposure prophylaxis (PrEP) strategies with proven in vivo efficacy rely on antiretroviral drugs, creating the potential for drug resistance and complicated treatment options in individuals who become infected.
Publikováno v:
Heliyon
Heliyon, Vol 5, Iss 10, Pp e02698-(2019)
Heliyon, Vol 5, Iss 10, Pp e02698-(2019)
Carbon fibre composites offer considerable potential for mass reduction in automotive applications. However, raw material cost is one of the major factors that constraints its extensive use in this mass market. Here we report a systematic study that
Autor:
Francis Dayton, Patricia Tang, Hak-Kim Chan, Isra Khatib, Juanfang Ruan, David Cipolla, James Blanchard
Publikováno v:
International Journal of Pharmaceutics
The present study was conducted to harness spray drying technology as a novel method of producing Ciprofloxacin nanocrystals inside liposomes (CNL) for inhalation delivery. Liposomal ciprofloxacin dispersions were spray dried with sucrose as a lyopro
Autor:
James Blanchard, Agegnehu Gettie, Ines Frank, Elena Martinelli, Melissa Robbiani, Natalia Guerra-Perez, Filippo Veglia, Diana J. Goode, Meropi Aravantinou
Publikováno v:
The Journal of Immunology. 194:2415-2423
The tissue microenvironment shapes the characteristics and functions of dendritic cells (DCs), which are important players in HIV infection and dissemination. Notably, DCs in the gut have the daunting task of orchestrating the balance between immune
Autor:
Al Ozonoff, Raina N. Fichorova, Joe M. Beaurline, Dhohyung Kim, John P. Vasilakos, Cecily C. Midkiff, Willemina Foppen, Simon D. van Haren, Lynn Fresh, Terese B. Theriot, James Blanchard, Christy J. Mancuso, Mark A. Tomai, Annette Scheid, Dmitri Smirnov, David J. Dowling, Andrew A. Lackner, Margaret H. Gilbert, Xavier Alvarez, Ofer Levy, Pyone P. Aye, Ilana Bergelson
Publikováno v:
JCI insight. 2(6)
Infection is the most common cause of mortality in early life, and immunization is the most promising biomedical intervention to reduce this burden. However, newborns fail to respond optimally to most vaccines. Adjuvantation is a key approach to enha
Autor:
Kumar Sridharan, Zhenqiang Ma, Todd M. Allen, Darryl P. Butt, Solomon Mikael, James Blanchard, Hongyi Mi
Publikováno v:
Journal of Nuclear Materials. 445:7-11
In order to observe Zircaloy-4 (Zr-4) cladding oxidation within a spent fuel canister, cladding oxidized in air at 500 °C was investigated by micro-Raman spectroscopy to measure the oxide layer thickness. Systematic Raman scans were performed to stu
Autor:
Darryl P. Butt, Kumar Sridharan, Solomon Mikael, Jung-Hun Seo, Edward Swinnich, Shaoqin Gong, Todd R. Allen, Hongyi Mi, James Blanchard, Zhenqiang Ma, Sean M. McDeavitt
Publikováno v:
Nano. 13:1850015
As the expected life of dry cask storage installations increases, it becomes increasingly desirable to monitor the state and performance of the cask internals to ensure that they continue to safely contain the radioactive materials in the fuel. One a
Autor:
Kristina Rodriguez, Chasity D. Andrews, Martin Markowitz, Hiroshi Mohri, Agegnehu Gettie, Cecilia Cheng-Mayer, David D. Ho, Mar Boente-Carrera, Kasi E. Russell-Lodrigue, Zhi Hong, William Spreen, Leslie St. Bernard, Yun Lan Yueh, James Blanchard, Susan L. Ford
Publikováno v:
Science Translational Medicine. 7
Long-acting GSK1265744 (GSK744 LA) is a strand transfer inhibitor of the HIV/SIV (simian immunodeficiency virus) integrase and was shown to be an effective preexposure prophylaxis (PrEP) agent in a low-dose intrarectal SHIV (simian-human immunodefici