Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Eckhard Wolf"'
Autor:
Arne Hinrichs, Jacopo Burrello, Mirko Peitzsch, Na Sun, Axel Walch, Konrad Fischer, Twinkle Vohra, Eckhard Wolf, Elisabeth Kemter, Daniel Teupser, Isabella-Sabrina Kinker, Celso E. Gomez-Sanchez, Jun Wang, Graeme Eisenhofer, Tracy Ann Williams, Britta Dobenecker, Martin Reincke, Elise P. Gomez-Sanchez, Angelika Schnieke
Publikováno v:
Hypertension
Hypertension 76, 1769-1777 (2020)
Hypertension 76, 1769-1777 (2020)
Primary aldosteronism is a frequent form of endocrine hypertension caused by aldosterone overproduction from the adrenal cortex. Regulation of aldosterone biosynthesis has been studied in rodents despite differences in adrenal physiology with humans.
Autor:
Martin Bidlingmaier, Andreas Blutke, Birgit Rathkolb, Mattias Backman, Arne Hinrichs, Eckhard Wolf, Evamaria O. Riedel, Martin Hrabĕ de Angelis, Maik Dahlhoff, Elisabeth Kemter, Jochen Schopohl, Jerzy Adamski, Thomas Fröhlich, Simone Renner, Cornelia Prehn, Georg J. Arnold
Publikováno v:
Molecular Metabolism, Vol 36, Iss, Pp-(2020)
Molecular Metabolism
Mol. Metab. 36:100978 (2020)
Molecular Metabolism
Mol. Metab. 36:100978 (2020)
Objective The liver is a central target organ of growth hormone (GH), which stimulates the synthesis of insulin-like growth factor 1 (IGF1) and affects multiple biochemical pathways. A systematic multi-omics analysis of GH effects in the liver has no
Autor:
Juan Antonio Aguilar-Pimentel, Thomas Klopstock, Eckhard Wolf, Carsten B. Schmidt-Weber, Julia Calzada-Wack, Ralph Fingerhut, Lore Becker, Marie Lucienne, Valerie Gailus-Durner, D. Sean Froese, Nadine Spielmann, Wolfgang Wurst, Philipp Mayer-Kuckuk, Birgit Rathkolb, Lillian Garrett, Martin Hrabě de Angelis, Déborah Mathis, Jan Rozman, Matthias R. Baumgartner, Merima Forny, Dirk H. Busch, Irina Treise, Patricia da Silva-Buttkus, Helmut Fuchs, Oana V. Amarie, Sabine M. Hölter
Publikováno v:
Biochimica et biophysica acta / Molecular basis of disease 1866(3), 165622 (2020). doi:10.1016/j.bbadis.2019.165622
Biochim. Biophys. Acta-Mol. Basis Dis. 1866:165622 (2020)
Biochim. Biophys. Acta-Mol. Basis Dis. 1866:165622 (2020)
Isolated methylmalonic aciduria (MMAuria) is primarily caused by deficiency of methylmalonyl-CoA mutase (MMUT or MUT). Biochemically, MUT deficiency results in the accumulation of methylmalonic acid (MMA), propionyl-carnitine (C3) and other metabolit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3c74a41bb0ba27f5045f882d95511bc
Autor:
Pierre Gianello, Francesco Nicotra, András Wirth, Julianna Kobolák, Suchitra Muenthaisong, Andrea Schnur, Andras Dinnyes, Yi Qiu, Elisabeth Kemter, Laura Russo, Charles-Thibault Burcez, Neal C. Burton, Peter Bartenstein, Sibylle Ziegler, Gabor Nemeth, Eckhard Wolf, Clemens C. Cyran, Eszter Prepost
Publikováno v:
Cell Proliferation
Cell proliferation, Vol. 53, no. 5, p. e12785 [1-9] (2020)
Cell proliferation, Vol. 53, no. 5, p. e12785 [1-9] (2020)
Regenerative medicine using human or porcine β‐cells or islets has an excellent potential to become a clinically relevant method for the treatment of type‐1 diabetes. High‐resolution imaging of the function and faith of transplanted porcine pa
Autor:
Raphaela Kübeck, Eckhard Wolf, Martina Gimpfl, Annette Seibt, Martin Klingenspor, Maik Dahlhoff, Andreas Blutke, Birgit Rathkolb, Soner Öner-Sieben, Jan Rozman, Regina Ensenauer, Martin Hrabě de Angelis, Adelbert A. Roscher
Publikováno v:
Biochim. Biophys. Acta-Mol. Basis Dis. 1863, 1605-1614 (2017)
Peri-conceptional exposure to maternal obesogenic nutrition is associated with in utero programming of later-life overweight and metabolic disease in the offspring. We aimed to investigate whether dietary intervention with a modified fatty acid quali
Autor:
Maximilian K. Marschall, Andrea Ofner, Marlon R. Schneider, Andreas Herbst, Felix Hiltwein, Jens Neumann, Jessica I. Grill, Frank T. Kolligs, Heike Zierahn, Eckhard Wolf
Publikováno v:
Molecular and Cellular Endocrinology. 439:286-296
To investigate the role of DRO1 in obesity and adipogenesis in vivo, we generated a constitutive Dro1 knockout mouse model and analyzed the effect of DRO1 loss on body growth under standard and high fat diet feeding conditions. Loss of DRO1 resulted
Autor:
Jerzy Adamski, Martin Hrabé de Angelis, Sabine M. Hölter, Helmut Fuchs, Dirk H. Busch, Thomas Klopstock, Lore Becker, Sabine Windhorst, Eckhard Wolf, Julia Calzada-Wack, Christine Blechner, Cornelia Prehn, Valerie Gailus-Durner, Michael J. Schmeisser, Lillian Garrett, Birgit Rathkolb, Susanne Conrad, Fabio Morellini, Thure Adler
Publikováno v:
Neuroscience letters 735, 135206-(2020). doi:10.1016/j.neulet.2020.135206
Inositol-1,4,5-trisphosphate 3-kinase-A (ITPKA) is the neuronal isoform of ITPKs and exhibits both actin bundling and InsP3kinase activity. In addition to neurons, ITPKA is ectopically expressed in tumor cells, where its oncogenic activity increases
Autor:
Istvan Novak, Martin Hrabĕ de Angelis, Eckhard Wolf, Georg Dhom, Britta Dobenecker, Timo D. Müller, Anna Götz, Armin M. Scholz, Steffanie Senf, Matthias H. Tschöp, Birgit Rathkolb, Brian Finan, Ellen Kienzle, Christoffer Clemmensen, Mathias Ritzmann, Andreas Blutke, Richard D. DiMarchi, Simone Renner, Susanne Zöls, Rüdiger Wanke, Mirjam Roth, Susanna M. Hofmann, Maren Bernau
Publikováno v:
Mol. Metab., DOI: 10.1016/j.molmet.2018.06.015 (2018)
Molecular Metabolism, Vol 16, Iss, Pp 180-190 (2018)
Molecular Metabolism, Vol 16, Iss, Pp 180-190 (2018)
Objective: The worldwide prevalence of obesity has increased to 10% in men and 15% in women and is associated with severe comorbidities such as diabetes, cancer, and cardiovascular disease. Animal models of obesity are central to experimental studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d06f94c47c106ec3a39510589fec9e69
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=53746
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=53746
Autor:
Ingrid Renner-Müller, Bernd Kost, Eckhard Wolf, Ansgar Brüning, Marlene Weiß, Ioannis Mylonas
Publikováno v:
Cardiovascular Toxicology. 16:90-99
The non-nucleoside reverse transcriptase inhibitor efavirenz is a widely prescribed antiretroviral drug used in combined antiretroviral therapy. Despite being an essential and life-saving medication, the required lifelong use of HIV drugs has been as
Autor:
Eckhard Wolf, Jessica I. Grill, Jens Neumann, Frank T. Kolligs, Heike Zierahn, Andreas Herbst, Andrea Ofner, Maximilian K. Marschall
Publikováno v:
Carcinogenesis. 39(9)
Colorectal carcinogenesis is a progressive multistep process involving the sequential accumulation of genetic alterations in tumor suppressor genes and oncogenes. Downregulated by oncogenes 1 (Dro1/Ccdc80) has been shown to be a potent tumor suppress