Zobrazeno 1 - 10
of 12
pro vyhledávání: '"David G. Hoel"'
Autor:
Fabiana Manservisi, Fiorella Belpoggi, Michela Padovani, Livio Giuliani, Morando Soffritti, Eva Tibaldi, David G. Hoel, Laura Falcioni, Michelina Lauriola, Luciano Bua, Marco Manservigi
Publikováno v:
American Journal of Industrial Medicine. 59:509-521
Background Experimental rodent bioassays performed up to now have failed to provide conclusive confirmation of the carcinogenicity of extremely low frequency magnetic fields (ELFMF). Objectives To evaluate the potential synergistic carcinogenic effec
Autor:
Lawrence C. Mohr, Apryl Bronley-DeLancey, David J. Jollow, David G. Hoel, JoEllyn M McMillan, David C. McMillan
Publikováno v:
Environmental Health Perspectives
BACKGROUND: Trichloroethylene (TCE) is a suspected human carcinogen and a common groundwater contaminant. Chloral hydrate (CH) is the major metabolite of TCE formed in the liver by cytochrome P450 2E1. CH is metabolized to the hepatocarcinogen trichl
Autor:
Paul J. Nietert, Susan E. Sutherland, Richard M. Silver, Rebecca G. Knapp, Janardan P. Pandey, David G. Hoel, Mustafa Dosemeci
Publikováno v:
Arthritis & Rheumatism. 41:1111-1118
Objective The primary objective was to determine whether occupational exposure to organic solvents is related to an increased risk of systemic sclerosis (SSc; scleroderma). Methods Occupational histories were obtained from 178 SSc patients and 200 co
Publikováno v:
Mathematical Biosciences. 149:107-136
When ionizing radiation strikes a cell it induces DNA double strand breaks (DSBs). Subsequently, some of the DSBs misrejoin and thus cause alterations in the size distribution of the DNA fragments. We derive a system of non-linear integro-differentia
Autor:
David C. McMillan, Jeffrey W. Fisher, James V. Bruckner, David J. Jollow, Lawrence C. Mohr, David G. Hoel
Publikováno v:
Critical reviews in toxicology. 39(9)
Trichloroethylene (TCE) is a widespread environmental contaminant that is carcinogenic when given in high, chronic doses to certain strains of mice and rats. The capacity of TCE to cause cancer in humans is less clear. The current maximum contaminant
Autor:
David G. Hoel, Roger O. McClellan, Richard Reiss, Carroll E. Cross, Elizabeth L. Anderson, Suresh H. Moolgavkar, George Hidy
Publikováno v:
Inhalation toxicology. 19(5)
Ambient particulate matter (PM) is a complex mixture of inorganic and organic compounds. The U.S. Environmental Protection Agency (EPA) regulates PM as a criteria pollutant and promulgates National Ambient Air Quality Standards for it. The PM indicat
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 20(4)
Predictive Strategies for Selecting 379 NCI/NTP Chemicals Evaluated for Carcinogenic Potential: Scientific and Public Health Impact. Fung, V. A., Huff, J. H., Weisburger, E. K., and Hoel, D. G. (1993). Fundam. Appl. Toxicol. 20, 413-436. The a priori
Autor:
Tomas Radivoyevitch, David G. Hoel, Philip J. Hahnfeldt, Björn Rydberg, Rainer K. Sachs, Bjorn Rydberg
Publikováno v:
Radiation Research. 149:52
The temporal evolution of unrejoined and misrejoined DNA double-strand breaks (DSBs) produced by high doses (80-160 Gy) of X rays has been estimated using pulsed-field gel electrophoresis (PFGE) (Lobrich et al., Proc. Natl. Acad. Sci. USA 92, 12050-1
Publikováno v:
Toxicology and Applied Pharmacology. 55:154-161
A general scheme is proposed which relates the carcinogenic responses to the amount of DNA-carcinogen adduct formed instead of applied dose. Based on the present understanding of the mechanism of carcinogenesis, we believe this to be a more rational
Autor:
David G. Hoel, Walter W. Piegorsch
Publikováno v:
Mutation Research/Reviews in Genetic Toxicology. 196:161-175
Salmonella mutagenic and rodent carcinogenic potencies are calculated for 112 compounds recently studied by the U.S. National Toxicology Program. 28 of the 112 compounds are seen to exhibit simultaneous non-zero mutagenic and carcinogenic potencies.