Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ingrid B. Borecki"'
Autor:
Cashell E. Jaquish, Craig P. Hersh, Emily Barron-Casella, Larry Phillips, James S. Pankow, JoAnn E. Manson, Mariza de Andrade, Vivien A. Sheehan, Norann A. Zaghloul, Yongmei Liu, Sergei Nekhai, Russell P. Tracy, Bruce S. Weir, Pankaj Qasba, Adrienne M. Stilp, Tasha E. Fingerlin, Heather M. Ochs-Balcom, L. Adrienne Cupples, Rongze Yang, David A. Schwartz, Shannon Kelly, Scott E. Devine, Tanja Smith, G.L. Kinney, Beverly Snively, Kent D. Taylor, Manolis Kellis, Ruth J. F. Loos, Seth A. Ament, Kathleen C. Barnes, Robert C. Kaplan, Ulrich Broeckel, Hemant K. Tiwari, Karin F. Hoth, Peter Durda, Julie L. Mikulla, Charles B. Eaton, Cotton Seed, Merry Lynn McDonald, Eric Boerwinkle, Josh Smith, Honghuang Lin, Ingrid B. Borecki, Jeffrey L. Curtis, Emelia J. Benjamin, Kenneth Rice, Sharon L.R. Kardia, Nicholas L. Smith, Coleen M. Damcott, Jeffrey Haessler, Kimberly L. Jones, Elaine Cornell, Nona Sotoodehnia, Adolfo Correa, Rich Johnston, C. Charles Gu, Chii Min Hwu, Peter C. Anderson, Lesley F. Tinker, Colleen Davis, R. Graham Barr, Scott T. Weiss, Leanna Farnam, Chao Hsiung, Brian Silver, Patrick F. McArdle, Lisa W. Martin, Yii-Der Ida Chen, John Barnard, Holly Kramer, Sekar Kathiresan, Gonçalo R. Abecasis, Barry Make, Michael C. Mahaney, Marco V Perez, Donna K. Arnett, Mark Chaffin, Xiuqing Guo, Joshua C. Bis, Pamela Russell, Paul L. Auer, James G. Wilson, Marilyn J. Telen, David K. Levine, Jennifer A. Smith, Christopher Scheller, Meher Preethi Boorgula, Aakrosh Ratan, Kari E. North, Dan E. Arking, Elizabeth A. Regan, Margaret G. Parker, Andres Metspalu, Jai G. Broome, Daniel Taliun, Lynette Ekunwe, Alyna T. Khan, Hao Mei, Dhananjay Vaidya, Ellen M. Schmidt, Stanford Mwasongwe, Joshua P. Lewis, Stacey Gabriel, Christine E. Seidman, Margery Gass, Deborah A. Nickerson, Nicola L. Hawley, Rebecca L. Beer, Afshin Parsa, Steven L. Salzberg, Terri H. Beaty, Stella Aslibekyan, Girish N. Nadkarni, Wei Zhao, David L. Tirschwell, Karen Bunting, Dawn L. DeMeo, Laura J. Rasmussen-Torvik, Julia Powers Becker, Dmitry Prokopenko, Karen Schwander, Bruce D. Gelb, Stephanie Krauter, Laura M. Raffield, Michael E. Hall, Frank C. Sciurba, Lauren Margolin, Nora Franceschini, Daniel N. Harris, Seyedeh M. Zekavat, Dawood Darbar, Keng-Han Lin, Haley Huston, Steven A. Lubitz, Andrea Ganna, Carole Sztalryd, Cathy C. Laurie, Christy Chang, James E. Hixson, Steven A. McCarroll, Barbara A. Konkle, Michael D. Kessler, Scott I. Vrieze, Yingze Zhang, Sarah Ruuska, George J. Papanicolaou, Weiniu Gan, Maris Alver, Elizabeth A. Streeten, Fei Fei Wang, Lu-Chen Weng, Braxton D. Mitchell, Lee-Ming Chuang, Sean P. David, Wei-Min Chen, Susan R. Heckbert, Ryan D. Hernandez, Andrew D. Johnson, Cristen J. Willer, Ani Manichaikul, Jonathan M. Bloom, Timothy D. O’Connor, Sylvia Smoller, Marguerite R. Irvin, Seung Hoan Choi, Ida Surakka, Veikko Salomaa, Diane M. Becker, Ron Do, W. Craig Johnson, Cecelia A. Laurie, Meryl S. LeBoff, Aniket Shetty, Tõnu Esko, Michael C. Zody, Xiaoqi Geng, Da Wei Gong, Snow Xueyan Zhao, Esteban G. Burchard, Xiuwen Zheng, Cara L. Carty, Alexander P. Reiner, Tim Assimes, Deborah A. Meyers, Mina K. Chung, Harald H H Göring, Benjamin M. Neale, Pradeep Natarajan, Yan Gao, Stephen S. Rich, Yun Ju Sung, Susan K. Dutcher, Ferdouse Begum, Stephanie M. Gogarten, John Blangero, Jonathan Cardwell, Kayleen Williams, Rakhi P. Naik, Amol C. Shetty, Sayantan Das, Myriam Fornage, May E. Montasser, Michelle Daya, Edwin K. Silverman, Daniel E. Weeks, Laura J. Kaufman, Dimitrios Avramopoulos, Michael Y. Tsai, Christine M. Albert, Vijay G. Sankaran, Jeffrey R. O'Connell, Thomas W. Blackwell, Stephen T. McGarvey, Robert M. Reed, Leslie A. Lange, Qing Duan, Bruce M. Psaty, Leslie S. Emery, Bertha Hidalgo, Jennifer A. Brody, L. Keoki Williams, Soren Germer, Zhaohui S. Qin, Deepti Jain, Deborah Applebaum-Bowden, Carla Wilson, Degui Zhi, Christoph Lange, Elliott Hong, L.F. Bielak, Wen Jane Lee, Yue Guan, Tarik Walker, Rebecca D. Jackson, Charles R. Farber, Mark J. Daly, Stephanie M. Fullerton, John E. Hokanson, Karol E. Watson, James Luo, Richard Casaburi, Seunggeun Lee, Jill M. Johnsen, Margaret A. Taub, Ryan L. Minster, Ravi Duggirala, Susan K. Mathai, Yun Li, Quenna Wong, Matthew Flickinger, Huichun Xu, Susan Redline, Ulrike Peters, Ivana V. Yang, Jesse M. Engreitz, Sanni Ruotsalainen, Sean K. McFarland, Avram D Walts, Patricia A. Peyser, Allison E. Ashley-Koch, Lewis C. Becker, Nicholette Palmer Allred, James A. Perry, Jody S. Sylvia, Tamar Sofer, Vasan S. Ramachandran, Laura Almasy, Matthew J. Budoff, Ranjan Deka, David M. Herrington, Simeon I. Taylor, Daniel Levy, Chaojie Yang, Sameer Chavan, Kathleen A. Ryan, Josyf C. Mychaleckyj, Ingo Ruczinski, Sebastian Zoellner, Michael Preuss, Tim Poterba, Wendy S. Post, Amber L. Beitelshees, Ben Heavner, Carolina Roselli, Namiko Abe, Jonathon LeFaive, Mark T. Gladwin, Brian Custer, Robert B. Wallace, Simin Liu, Michael H. Cho, Robert E. Handsaker, Dabeeru C. Rao, Bo Juen Chen, Wayne Hui Heng Sheu, Xiang Zhou, Marcos Bezerra, Solomon K. Musani, Eimear E. Kenny, James F. Casella, Kathryn L. Lunetta, Nancy Min, Nicholas Rafaels, Lisa R. Yanek, Min A. Jhun, David C. Glahn, Rasika A. Mathias, Mollie A. Minear, Russell P. Bowler, Jason Ernst, Carolyn J. Crandall, Sara Penchev, Alvaro Alonso, Timothy A. Thornton, Toni I. Pollin, Charles Kooperberg, Ethan M. Lange, Juan M. Peralta, Pramod Anugu, Lucinda Fulton, Adam A. Szpiro, Michael R. DeBaun, M. Benjamin Shoemaker, Sam Phillips, Dan M. Roden, Mao Fu, Daniel I. Chasman, James D. Crapo, Hua Tang, Gina M. Peloso, Hyun Min Kang, Samuli Ripatti, Phuwanat Sakornsakolpat, Christopher R. Gignoux, Peter VandeHaar, Jerome I. Rotter, Dandi Qiao, Emily S. Wan, Shabnam Salimi, Kevin Sandow, Jiang He, Patrick T. Ellinor, Joanne E. Curran
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature communications, vol 9, iss 1
Nature Communications
Nature communications, vol 9, iss 1
Nature Communications
Lipoprotein(a), Lp(a), is a modified low-density lipoprotein particle that contains apolipoprotein(a), encoded by LPA, and is a highly heritable, causal risk factor for cardiovascular diseases that varies in concentrations across ancestries. Here, we
Autor:
Michael A. Province, Hemant K. Tiwari, Bertha Hidalgo, Mary F. Feitosa, Degui Zhi, Paul N. Hopkins, Ingrid B. Borecki, Stella Aslibekyan, Robert J. Straka, Alexis C. Frazier-Wood, Marguerite R. Irvin, Xin Geng, Ping An, Kathleen A. Ryan, Braxton D. Mitchell, Jose M. Ordovas, Vinodh Srinivasasainagendra, Donna K. Arnett, Tushar Dave
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 4, Pp 722-729 (2018)
Our understanding of genetic influences on the response of lipids to specific interventions is limited. In this study, we sought to elucidate effects of rare genetic variants on lipid response to a high-fat meal challenge and fenofibrate (FFB) therap
Autor:
Benjamin F. Voight, Stefania Bandinelli, Pascal Bovet, Latonya F. Been, Ci Song, Luigi Ferrucci, Johannes Kettunen, Andrew D. Morris, Mary Susan Burnett, Ronald M. Krauss, Igor Rudan, Heleen M. den Hertog, Stavroula Kanoni, G. Kees Hovingh, Elina Hyppönen, Kauko Heikkilä, Richard S. Cooper, Daniel I. Chasman, Bruna Gigante, Stefan Gustafsson, Jian'an Luan, Sarah H. Wild, Patricia B. Munroe, Göran Hallmans, Jeffrey R. O'Connell, Danish Saleheen, Aarno Palotie, Leena Moilanen, Jerome I. Rotter, Caroline Hayward, Jennifer L. Bragg-Gresham, Nicholas G. Martin, Claudia Langenberg, George Dedoussis, Carlo Sidore, Ulf Gyllensten, Marika Kaakinen, Jing Hua Zhao, Aimo Ruokonen, Diana Kuh, Maria Dimitriou, Shih-Yi Lin, Gina M. Peloso, Marcus E. Kleber, Christopher J. Groves, Alena Stančáková, Michel Burnier, Patrik K. E. Magnusson, John C. Chambers, Giancarlo Cesana, Francis S. Collins, Gabrielle Müller, Angela Döring, Colin A. McKenzie, Paul Elliott, Lars Lind, Vilmundur Gudnason, Dharambir K. Sanghera, Jean Ferrières, Toshiko Tanaka, Stefan R. Bornstein, Gershim Asiki, Jacques S. Beckmann, Anneli Pouta, Timo A. Lakka, Daniel J. Rader, Elizabeth H. Young, Kelly A. Volcik, Dena G. Hernandez, Ann-Kristin Petersen, Kristian Hveem, Amy J. Swift, Murielle Bochud, Pierre Meneton, Paul M. Ridker, Kathleen Stirrups, Stephen S. Rich, Isleifur Olafsson, Ruth J. F. Loos, Serena Sanna, Markus Perola, Meena Kumari, Cameron D. Palmer, Carlos Iribarren, Nancy L. Pedersen, Mark O. Goodarzi, Panos Deloukas, Norman Klopp, Cristina Pomilla, Stephen E. Epstein, Antti Jula, Themistocles L. Assimes, Martina Müller-Nurasyid, Marjo-Riitta Järvelin, Chao A. Hsiung, Sonia Shah, Christian Gieger, Toby Johnson, Cornelia M. van Duijn, Samuli Ripatti, Nicholas J. Wareham, Krista Fischer, Wendy L. McArdle, Linda S. Adair, Kay-Tee Khaw, Bruce M. Psaty, André G. Uitterlinden, Aaron Isaacs, Tõnu Esko, Jennifer L. Bolton, Rebecca N. Nsubuga, Eric Boerwinkle, L. Joost van Pelt, Jouko Saramies, François Mach, Pierre Fontanillas, Teresa Ferreira, Lars Wallentin, Michael Boehnke, Christa Meisinger, Wayne Huey-Herng Sheu, Gonçalo R. Abecasis, Inês Barroso, Franklyn I. Bennett, Dmitry Shungin, Jaakko Kaprio, Kirsten Ohm Kyvik, Deepti Gurdasani, Anne U. Jackson, Paolo Brambilla, Georg Ehret, Cecilia M. Lindgren, Fernando Rivadeneira, Theodore Papamarkou, Jaakko Tuomilehto, Cristen J. Willer, Martin L. Buchkovich, Antero Kesäniemi, Hubert Scharnagl, Xiaohui Li, Elena Tremoli, Nelson B. Freimer, Mika Kähönen, Ron Do, Karen L. Mohlke, Thomas Illig, Gudmar Thorleifsson, Peter J. Koudstaal, Andres Metspalu, Ulf de Faire, Dominique Arveiler, Harald Grallert, Jaana Lindström, Laurence Tiret, Jaspal S. Kooner, Braxton D. Mitchell, Sebanti Sengupta, Gonneke Willemsen, Anna-Liisa Hartikainen, Terho Lehtimäki, Steve E. Humphries, Peter Schwarz, Dorret I. Boomsma, Harry Campbell, Ellen M. Schmidt, Tom Wilsgaard, Janet Seeley, Alex S. F. Doney, Alan R. Shuldiner, John Whitfield, Markku Laakso, Peter Vollenweider, Gudmundur I. Eyjolfsson, Winfried März, Mika Kivimäki, Ying Wu, Johanna Kuusisto, Andrew A. Hicks, Bruce H. R. Wolffenbuttel, May E. Montasser, Bamidele O. Tayo, Unnur Thorsteinsdottir, Muredach P. Reilly, Leo-Pekka Lyytikäinen, Eric Kim, John Danesh, Ida Surakka, Åsa Johansson, Anders Hamsten, Thomas Quertermous, Hsing-Yi Chang, Jin Chen, Agneta Siegbahn, Narisu Narisu, Samia Mora, Erik Ingelsson, Colin N. A. Palmer, Sekar Kathiresan, Manjinder S. Sandhu, Leif Groop, Jose M. Ordovas, Alan B. Feranil, Evelin Mihailov, Hilma Holm, Pontiano Kaleebu, Lindsay L. Waite, Ramaiah Nagaraja, Andrew Wong, Rona J. Strawbridge, David P. Strachan, Yii-Der Ida Chen, Tamara B. Harris, Jackie F. Price, Aravinda Chakravarti, Veikko Salomaa, Sailaja Vedantam, Albert Hofman, Devin Absher, Ross M. Fraser, Kaisa Silander, Pirjo Komulainen, Yi Jen Hung, Peter P. Pramstaller, Kari Stefansson, Aroon D. Hingorani, Tanya M. Teslovich, Matti Uusitupa, L. Adrienne Cupples, Cisca Wijmenga, Lori L. Bonnycastle, Ilja M. Nolte, Andrea Ganna, Ken K. Ong, Inger Njølstad, Bernhard O. Boehm, Nicholas W.J. Wainwright, Richa Saxena, Rainer Rauramaa, Louise A. Donnelly, James F. Wilson, Matthew Jones, Ingrid B. Borecki, Steven C. Hunt, Weihua Zhang, Massimo Mangino, John J.P. Kastelein, Martha L. Gravito, Mark I. McCarthy, Evita G. Van Den Herik, Joel N. Hirschhorn, Nilesh J. Samani, Daniel F. Freitag, Ayse Demirkan, Mary F. Feitosa, Tuomo Nieminen, Tim D. Spector, Paul W. Franks, Chris Power
Publikováno v:
Nature Genetics; Vol 45
Nature Genetics, 45(11), 1274-1283. Nature Publishing Group
Willer, C J, Schmidt, E M, Sengupta, S, Peloso, G M, Gustafsson, S, Kanoni, S, Ganna, A, Chen, J, Buchkovich, M L, Mora, S, Beckmann, J S, Bragg-Gresham, J L, Chang, H-Y, Demirkan, A, Den Hertog, H M, Do, R, Donnelly, L A, Ehret, G B, Esko, T, Feitosa, M F, Ferreira, T, Fischer, K, Fontanillas, P, Fraser, R M, Freitag, D F, Gurdasani, D, Heikkilä, K, Hyppönen, E, Isaacs, A, Jackson, A U, Johansson, A, Johnson, T, Kaakinen, M, Kettunen, J, Kleber, M E, Li, X, Luan, J, Lyytikäinen, L-P, Magnusson, P K E, Mangino, M, Mihailov, E, Montasser, M E, Bolton, J L, Hayward, C, Rudan, I, Wild, S H, Wilson, J F, Campbell, H & Morris, A & Price, J F 2013, ' Discovery and refinement of loci associated with lipid levels ', Nature Genetics, vol. 45, no. 11, pp. 1274-83 . https://doi.org/10.1038/ng.2797
Nature genetics
Nature genetics, 45(11), 1274-1283. Nature Publishing Group
Nature Genetics, Vol. 45, No 11 (2013) pp. 1274-83
Nature Genetics, 45(11), 1274-+. Nature Publishing Group
NATURE GENETICS
Willer, C J, Schmidt, E M, Sengupta, S, Peloso, G M, Gustafsson, S, Kanoni, S, Ganna, A, Chen, J, Buchkovich, M L, Mora, S, Beckmann, J S, Bragg-Gresham, J L, Chang, H Y, Demirkan, A, den Hertog, H M, Do, R, Donnelly, L A, Ehret, G B, Esko, T, Feitosa, M F, Ferreira, T, Fischer, K, Fontanillas, P, Fraser, R M, Freitag, D F, Gurdasani, D, Heikkilä, K, Hyppönen, E, Isaacs, A, Jackson, A U, Johansson, A, Johnson, T, Kaakinen, M, Kettunen, J, Kleber, M E, Li, X, Luan, J, Lyytikäinen, L P, Magnusson, P K, Mangino, M, Mihailov, E, Montasser, M E, Müller-Nurasyid, M, Nolte, I M, O'Connell, J R, Palmer, C D, Perola, M, Petersen, A K, Sanna, S, Saxena, R, Service, S K, Shah, S, Shungin, D, Sidore, C, Song, C, Strawbridge, R J, Surakka, I, Tanaka, T, Teslovich, T M, Thorleifson, G, van den Herik, E G, Voight, B F, Volcik, K A, Waite, L L, Wong, A, Wu, Y, Zhang, W, Absher, D, Asiki, G, Barroso, I, Been, L F, Bolton, J L, Bonnycastle, L L, Brambilla, P, Burnett, M S, Cesana, G, Dimitriou, M, Doney, A S F, Döring, A, Elliott, P, Epstein, S E, Eyjolfsson, G I, Gigante, B, Goodarzi, M O, Grallert, H, Gravito, M L, Groves, C J, Hallmans, G, Hartikainen, A L, Hayward, C, Hernandez, D, Hicks, A A, Holm, H, Hung, Y J, Illig, T, Jones, M R, Kaleebu, P, Kastelein, J J, Khaw, K T, Kim, E, Klopp, N, Komulainen, P, Kumari, M, Langenberg, C, Lehtimäki, T, Lin, S Y, Lindström, J, Loos, R J, Mach, F, McArdle, W L, Meisinger, C, Mitchell, B D, Müller, G, Nagaraja, R, Narisu, N, Nieminen, T V, Nsubuga, R N, Olafsson, I, Ong, K K, Palotie, A, Papamarkou, T, Pomilla, C, Pouta, A, Rader, D J, Reilly, M P, Ridker, P M, Rivadeneira, F, Rudan, I, Ruokonen, A, Samani, N J, Scharnagl, H, Seeley, J, Silander, K, Stancakova, A, Stirrups, K, Swift, A J, Tiret, L, Uitterlinden, A G, van Pelt, L J, Vedantam, S, Wainwright, N W, Wijmenga, C, Wild, S H, Willemsen, G, Wilsgaard, T, Wilson, J F, Young, E H, Zhao, J H, Adair, L S, Arveiler, D, Assimes, T L, Bandinelli, S, Bennett, F, Bochud, M, Boehm, B O, Boomsma, D I, Borecki, I B, Bornstein, S R, Bovet, P, Burnier, M, Campbell, H, Chakravarti, A, Chambers, J C, Chen, Y D, Collins, F S, Cooper, R S, Danesh, J, Dedoussis, G, de Faire, U, Feranil, A B, Ferrières, J, Ferrucci, L, Freimer, N B, Gieger, C, Groop, L C, Gudnason, V, Gyllensten, U, Hamsten, A, Harris, T B, Hingorani, A D, Hirschhorn, J N, Hofman, A, Hovingh, K G, Hsiung, C A, Humphries, S E, Hunt, S C, Hveem, K, Iribarren, C, Järvelin, M R, Jula, A, Kähönen, M, Kaprio, J, Kesäniemi, A, Kivimaki, M, Kooner, J S, Koudstaal, P J, Krauss, R M, Kuh, D, Kuusisto, J, Kyvik, K O, Laakso, M, Lakka, T A, Lind, L, Lindgren, C M, Martin, N G, März, W, McCarthy, M I, McKenzie, C A, Meneton, P, Metspalu, A, Moilanen, L, Morris, A D, Munroe, P B, Njolstad, I, Pedersen, N L, Power, C, Pramstaller, P P, Price, J F, Psaty, B M, Quertermous, T, Rauramaa, R, Saleheen, D, Salomaa, V, Sanghera, D K, Saramies, J, Schwarz, P E, Sheu, W H, Shuldiner, A R, Siegbahn, A, Spector, T D, Stefansson, K, Strachan, D P, Tayo, B O, Tremoli, E, Tuomilehto, J, Uusitupa, M, van Duijn, C M, Vollenweider, P, Wallentin, L, Wareham, N J, Whitfield, J B, Wolffenbuttel, B H, Ordovas, J, Boerwinkle, E, Palmer, C N, Thorsteinsdottir, U, Chasman, D I, Rotter, J I, Franks, P W, Ripatti, S, Cupples, L A, Sandhu, M S, Rich, S S, Boehnke, M, Deloukas, P, Kathiresan, S, Mohlke, K L, Ingelsson, E & Abecasis, G R 2013, ' Discovery and refinement of loci associated with lipid levels ', Nature Genetics, vol. 45, no. 11, pp. 1274-1283 . https://doi.org/10.1038/ng.2797
Willer, C J, Schmidt, E M, Sengupta, S, Peloso, G M, Gustafsson, S, Kanoni, S, Ganna, A, Chen, J, Buchkovich, M L, Mora, S, Beckmann, J S, Bragg-Gresham, J L, Chang, H Y, Demirkan, A, Den Hertog, H M, Do, R, Donnelly, L A, Ehret, G B, Esko, T, Feitosa, M F, Ferreira, T, Fischer, K, Fontanillas, P, Fraser, R M, Freitag, D F, Gurdasani, D, Heikkila, K, Hypponen, E, Isaacs, A, Jackson, A U, Johansson, A, Johnson, T, Kaakinen, M, Kettunen, J, Kleber, M E, Li, X H, Luan, J A, Lyytikainen, L P, Magnusson, P K E, Mangino, M, Mihailov, E, Montasser, M E, Muller-Nurasyid, M, Nolte, I M, O'Connell, J R, Palmer, C D, Perola, M, Petersen, A K, Sanna, S, Saxena, R, Service, S K, Shah, S, Shungin, D, Sidore, C, Song, C, Strawbridge, R J, Surakka, I, Tanaka, T, Teslovich, T M, Thorleifsson, G, Van den Herik, E G, Voight, B F, Volcik, K A, Waite, L L, Wong, A, Wu, Y, Zhang, W H, Absher, D, Asiki, G, Barroso, I, Been, L F, Bolton, J L, Bonnycastle, L L, Brambilla, P, Burnett, M S, Cesana, G, Dimitriou, M, Doney, A S F, Doring, A, Elliott, P, Epstein, S E, Eyjolfsson, G I, Gigante, B, Goodarzi, M O, Grallert, H, Gravito, M L, Groves, C J, Hallmans, G, Hartikainen, A L, Hayward, C, Hernandez, D, Hicks, A A, Holm, H, Hung, Y J, Illig, T, Jones, M R, Kaleebu, P, Kastelein, J J P, Khaw, K T, Kim, E, Klopp, N, Komulainen, P, Kumari, M, Langenberg, C, Lehtimaki, T, Lin, S Y, Lindstrom, J, Loos, R J F, Mach, F, McArdle, W L, Meisinger, C, Mitchell, B D, Muller, G, Nagaraja, R, Narisu, N, Nieminen, T V M, Nsubuga, R N, Olafsson, I, Ong, K K, Palotie, A, Papamarkou, T, Pomilla, C, Pouta, A, Rader, D J, Reilly, M P, Ridker, P M, Rivadeneira, F, Rudan, I, Ruokonen, A, Samani, N, Scharnagl, H, Seeley, J, Silander, K, Stancakova, A, Stirrups, K, Swift, A J, Tiret, L, Uitterlinden, A G, van Pelt, L J, Vedantam, S, Wainwright, N, Wijmenga, C, Wild, S H, Willemsen, G, Wilsgaard, T, Wilson, J F, Young, E H, Zhao, J H, Adair, L S, Arveiler, D, Assimes, T L, Bandinelli, S, Bennett, F, Bochud, M, Boehm, B O, Boomsma, D I, Borecki, I B, Bornstein, S R, Bovet, P, Burnier, M, Campbell, H, Chakravarti, A, Chambers, J C, Chen, Y D I, Collins, F S, Cooper, R S, Danesh, J, Dedoussis, G, de Faire, U, Feranil, A B, Ferrieres, J, Ferrucci, L, Freimer, N B, Gieger, C, Groop, L C, Gudnason, V, Gyllensten, U, Hamsten, A, Harris, T B, Hingorani, A, Hirschhorn, J N, Hofman, A, Hovingh, G K, Hsiung, C A, Humphries, S E, Hunt, S C, Hveem, K, Iribarren, C, Jarvelin, M R, Jula, A, Kahonen, M, Kaprio, J, Kesaniemi, A, Kivimaki, M, Kooner, J S, Koudstaal, P J, Krauss, R M, Kuh, D, Kuusisto, J, Kyvik, K O, Laakso, M, Lakka, T A, Lind, L, Lindgren, C M, Martin, N G, Marz, W, McCarthy, M I, McKenzie, C A, Meneton, P, Metspalu, A, Moilanen, L, Morris, A D, Munroe, P B, Njolstad, I, Pedersen, N L, Power, C, Pramstaller, P P, Price, J F, Psaty, B M, Quertermous, T, Rauramaa, R, Saleheen, D, Salomaa, V, Sanghera, D K, Saramies, J, Schwarz, P E H, Sheu, W H H, Shuldiner, A R, Siegbahn, A, Spector, T D, Stefansson, K, Strachan, D P, Tayo, B O, Tremoli, E, Tuomilehto, J, Uusitupa, M, van Duijn, C M, Vollenweider, P, Wallentin, L, Wareham, N J, Whitfield, J B, Wolffenbuttel, B H R, Ordovas, J M, Boerwinkle, E, Palmer, C N A, Thorsteinsdottir, U, Chasman, D I, Rotter, J I, Franks, P W, Ripatti, S, Cupples, L A, Sandhu, M S, Rich, S S, Boehnke, M, Deloukas, P, Kathiresan, S, Mohlke, K L, Ingelsson, E, Abecasis, G R & Global Lipids Genetics, C 2013, ' Discovery and refinement of loci associated with lipid levels ', Nature Genetics, vol. 45, pp. 1274-1283 . https://doi.org/10.1038/ng.2797
Nature Genetics
Nature Genetics, vol. 45, no. 11, pp. 1274-1283
Nature Genetics, 45(11), 1274-1283. Nature Publishing Group
Willer, C J, Schmidt, E M, Sengupta, S, Peloso, G M, Gustafsson, S, Kanoni, S, Ganna, A, Chen, J, Buchkovich, M L, Mora, S, Beckmann, J S, Bragg-Gresham, J L, Chang, H-Y, Demirkan, A, Den Hertog, H M, Do, R, Donnelly, L A, Ehret, G B, Esko, T, Feitosa, M F, Ferreira, T, Fischer, K, Fontanillas, P, Fraser, R M, Freitag, D F, Gurdasani, D, Heikkilä, K, Hyppönen, E, Isaacs, A, Jackson, A U, Johansson, A, Johnson, T, Kaakinen, M, Kettunen, J, Kleber, M E, Li, X, Luan, J, Lyytikäinen, L-P, Magnusson, P K E, Mangino, M, Mihailov, E, Montasser, M E, Bolton, J L, Hayward, C, Rudan, I, Wild, S H, Wilson, J F, Campbell, H & Morris, A & Price, J F 2013, ' Discovery and refinement of loci associated with lipid levels ', Nature Genetics, vol. 45, no. 11, pp. 1274-83 . https://doi.org/10.1038/ng.2797
Nature genetics
Nature genetics, 45(11), 1274-1283. Nature Publishing Group
Nature Genetics, Vol. 45, No 11 (2013) pp. 1274-83
Nature Genetics, 45(11), 1274-+. Nature Publishing Group
NATURE GENETICS
Willer, C J, Schmidt, E M, Sengupta, S, Peloso, G M, Gustafsson, S, Kanoni, S, Ganna, A, Chen, J, Buchkovich, M L, Mora, S, Beckmann, J S, Bragg-Gresham, J L, Chang, H Y, Demirkan, A, den Hertog, H M, Do, R, Donnelly, L A, Ehret, G B, Esko, T, Feitosa, M F, Ferreira, T, Fischer, K, Fontanillas, P, Fraser, R M, Freitag, D F, Gurdasani, D, Heikkilä, K, Hyppönen, E, Isaacs, A, Jackson, A U, Johansson, A, Johnson, T, Kaakinen, M, Kettunen, J, Kleber, M E, Li, X, Luan, J, Lyytikäinen, L P, Magnusson, P K, Mangino, M, Mihailov, E, Montasser, M E, Müller-Nurasyid, M, Nolte, I M, O'Connell, J R, Palmer, C D, Perola, M, Petersen, A K, Sanna, S, Saxena, R, Service, S K, Shah, S, Shungin, D, Sidore, C, Song, C, Strawbridge, R J, Surakka, I, Tanaka, T, Teslovich, T M, Thorleifson, G, van den Herik, E G, Voight, B F, Volcik, K A, Waite, L L, Wong, A, Wu, Y, Zhang, W, Absher, D, Asiki, G, Barroso, I, Been, L F, Bolton, J L, Bonnycastle, L L, Brambilla, P, Burnett, M S, Cesana, G, Dimitriou, M, Doney, A S F, Döring, A, Elliott, P, Epstein, S E, Eyjolfsson, G I, Gigante, B, Goodarzi, M O, Grallert, H, Gravito, M L, Groves, C J, Hallmans, G, Hartikainen, A L, Hayward, C, Hernandez, D, Hicks, A A, Holm, H, Hung, Y J, Illig, T, Jones, M R, Kaleebu, P, Kastelein, J J, Khaw, K T, Kim, E, Klopp, N, Komulainen, P, Kumari, M, Langenberg, C, Lehtimäki, T, Lin, S Y, Lindström, J, Loos, R J, Mach, F, McArdle, W L, Meisinger, C, Mitchell, B D, Müller, G, Nagaraja, R, Narisu, N, Nieminen, T V, Nsubuga, R N, Olafsson, I, Ong, K K, Palotie, A, Papamarkou, T, Pomilla, C, Pouta, A, Rader, D J, Reilly, M P, Ridker, P M, Rivadeneira, F, Rudan, I, Ruokonen, A, Samani, N J, Scharnagl, H, Seeley, J, Silander, K, Stancakova, A, Stirrups, K, Swift, A J, Tiret, L, Uitterlinden, A G, van Pelt, L J, Vedantam, S, Wainwright, N W, Wijmenga, C, Wild, S H, Willemsen, G, Wilsgaard, T, Wilson, J F, Young, E H, Zhao, J H, Adair, L S, Arveiler, D, Assimes, T L, Bandinelli, S, Bennett, F, Bochud, M, Boehm, B O, Boomsma, D I, Borecki, I B, Bornstein, S R, Bovet, P, Burnier, M, Campbell, H, Chakravarti, A, Chambers, J C, Chen, Y D, Collins, F S, Cooper, R S, Danesh, J, Dedoussis, G, de Faire, U, Feranil, A B, Ferrières, J, Ferrucci, L, Freimer, N B, Gieger, C, Groop, L C, Gudnason, V, Gyllensten, U, Hamsten, A, Harris, T B, Hingorani, A D, Hirschhorn, J N, Hofman, A, Hovingh, K G, Hsiung, C A, Humphries, S E, Hunt, S C, Hveem, K, Iribarren, C, Järvelin, M R, Jula, A, Kähönen, M, Kaprio, J, Kesäniemi, A, Kivimaki, M, Kooner, J S, Koudstaal, P J, Krauss, R M, Kuh, D, Kuusisto, J, Kyvik, K O, Laakso, M, Lakka, T A, Lind, L, Lindgren, C M, Martin, N G, März, W, McCarthy, M I, McKenzie, C A, Meneton, P, Metspalu, A, Moilanen, L, Morris, A D, Munroe, P B, Njolstad, I, Pedersen, N L, Power, C, Pramstaller, P P, Price, J F, Psaty, B M, Quertermous, T, Rauramaa, R, Saleheen, D, Salomaa, V, Sanghera, D K, Saramies, J, Schwarz, P E, Sheu, W H, Shuldiner, A R, Siegbahn, A, Spector, T D, Stefansson, K, Strachan, D P, Tayo, B O, Tremoli, E, Tuomilehto, J, Uusitupa, M, van Duijn, C M, Vollenweider, P, Wallentin, L, Wareham, N J, Whitfield, J B, Wolffenbuttel, B H, Ordovas, J, Boerwinkle, E, Palmer, C N, Thorsteinsdottir, U, Chasman, D I, Rotter, J I, Franks, P W, Ripatti, S, Cupples, L A, Sandhu, M S, Rich, S S, Boehnke, M, Deloukas, P, Kathiresan, S, Mohlke, K L, Ingelsson, E & Abecasis, G R 2013, ' Discovery and refinement of loci associated with lipid levels ', Nature Genetics, vol. 45, no. 11, pp. 1274-1283 . https://doi.org/10.1038/ng.2797
Willer, C J, Schmidt, E M, Sengupta, S, Peloso, G M, Gustafsson, S, Kanoni, S, Ganna, A, Chen, J, Buchkovich, M L, Mora, S, Beckmann, J S, Bragg-Gresham, J L, Chang, H Y, Demirkan, A, Den Hertog, H M, Do, R, Donnelly, L A, Ehret, G B, Esko, T, Feitosa, M F, Ferreira, T, Fischer, K, Fontanillas, P, Fraser, R M, Freitag, D F, Gurdasani, D, Heikkila, K, Hypponen, E, Isaacs, A, Jackson, A U, Johansson, A, Johnson, T, Kaakinen, M, Kettunen, J, Kleber, M E, Li, X H, Luan, J A, Lyytikainen, L P, Magnusson, P K E, Mangino, M, Mihailov, E, Montasser, M E, Muller-Nurasyid, M, Nolte, I M, O'Connell, J R, Palmer, C D, Perola, M, Petersen, A K, Sanna, S, Saxena, R, Service, S K, Shah, S, Shungin, D, Sidore, C, Song, C, Strawbridge, R J, Surakka, I, Tanaka, T, Teslovich, T M, Thorleifsson, G, Van den Herik, E G, Voight, B F, Volcik, K A, Waite, L L, Wong, A, Wu, Y, Zhang, W H, Absher, D, Asiki, G, Barroso, I, Been, L F, Bolton, J L, Bonnycastle, L L, Brambilla, P, Burnett, M S, Cesana, G, Dimitriou, M, Doney, A S F, Doring, A, Elliott, P, Epstein, S E, Eyjolfsson, G I, Gigante, B, Goodarzi, M O, Grallert, H, Gravito, M L, Groves, C J, Hallmans, G, Hartikainen, A L, Hayward, C, Hernandez, D, Hicks, A A, Holm, H, Hung, Y J, Illig, T, Jones, M R, Kaleebu, P, Kastelein, J J P, Khaw, K T, Kim, E, Klopp, N, Komulainen, P, Kumari, M, Langenberg, C, Lehtimaki, T, Lin, S Y, Lindstrom, J, Loos, R J F, Mach, F, McArdle, W L, Meisinger, C, Mitchell, B D, Muller, G, Nagaraja, R, Narisu, N, Nieminen, T V M, Nsubuga, R N, Olafsson, I, Ong, K K, Palotie, A, Papamarkou, T, Pomilla, C, Pouta, A, Rader, D J, Reilly, M P, Ridker, P M, Rivadeneira, F, Rudan, I, Ruokonen, A, Samani, N, Scharnagl, H, Seeley, J, Silander, K, Stancakova, A, Stirrups, K, Swift, A J, Tiret, L, Uitterlinden, A G, van Pelt, L J, Vedantam, S, Wainwright, N, Wijmenga, C, Wild, S H, Willemsen, G, Wilsgaard, T, Wilson, J F, Young, E H, Zhao, J H, Adair, L S, Arveiler, D, Assimes, T L, Bandinelli, S, Bennett, F, Bochud, M, Boehm, B O, Boomsma, D I, Borecki, I B, Bornstein, S R, Bovet, P, Burnier, M, Campbell, H, Chakravarti, A, Chambers, J C, Chen, Y D I, Collins, F S, Cooper, R S, Danesh, J, Dedoussis, G, de Faire, U, Feranil, A B, Ferrieres, J, Ferrucci, L, Freimer, N B, Gieger, C, Groop, L C, Gudnason, V, Gyllensten, U, Hamsten, A, Harris, T B, Hingorani, A, Hirschhorn, J N, Hofman, A, Hovingh, G K, Hsiung, C A, Humphries, S E, Hunt, S C, Hveem, K, Iribarren, C, Jarvelin, M R, Jula, A, Kahonen, M, Kaprio, J, Kesaniemi, A, Kivimaki, M, Kooner, J S, Koudstaal, P J, Krauss, R M, Kuh, D, Kuusisto, J, Kyvik, K O, Laakso, M, Lakka, T A, Lind, L, Lindgren, C M, Martin, N G, Marz, W, McCarthy, M I, McKenzie, C A, Meneton, P, Metspalu, A, Moilanen, L, Morris, A D, Munroe, P B, Njolstad, I, Pedersen, N L, Power, C, Pramstaller, P P, Price, J F, Psaty, B M, Quertermous, T, Rauramaa, R, Saleheen, D, Salomaa, V, Sanghera, D K, Saramies, J, Schwarz, P E H, Sheu, W H H, Shuldiner, A R, Siegbahn, A, Spector, T D, Stefansson, K, Strachan, D P, Tayo, B O, Tremoli, E, Tuomilehto, J, Uusitupa, M, van Duijn, C M, Vollenweider, P, Wallentin, L, Wareham, N J, Whitfield, J B, Wolffenbuttel, B H R, Ordovas, J M, Boerwinkle, E, Palmer, C N A, Thorsteinsdottir, U, Chasman, D I, Rotter, J I, Franks, P W, Ripatti, S, Cupples, L A, Sandhu, M S, Rich, S S, Boehnke, M, Deloukas, P, Kathiresan, S, Mohlke, K L, Ingelsson, E, Abecasis, G R & Global Lipids Genetics, C 2013, ' Discovery and refinement of loci associated with lipid levels ', Nature Genetics, vol. 45, pp. 1274-1283 . https://doi.org/10.1038/ng.2797
Nature Genetics
Nature Genetics, vol. 45, no. 11, pp. 1274-1283
Levels of low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, triglycerides and total cholesterol are heritable, modifiable risk factors for coronary artery disease. To identify new loci and refine known loci influe
Autor:
Albert Hofman, Megan L. Grove, Jennifer A. Brody, Adolfo Correa, Kim Lawson, Jose M. Ordovas, Yingchang Lu, André G. Uitterlinden, Riccardo E. Marioni, Nathan O. Stitziel, Oscar H. Franco, Yongmei Liu, Ingrid B. Borecki, Aron Y. Joon, Lindsay M. Reynolds, Ozren Polasek, Kelli K. Ryckman, Muredach P. Reilly, Johanna Jakobsdottir, Abbas Dehghan, L. Adrienne Cupples, Tamara B. Harris, Michael Griswold, Judy Wang, Christopher S. Carlson, Caroline Hayward, Leslie A. Lange, Stephen S. Rich, Kenneth Rice, Jacy R Crosby, Diego Ardissino, Charles Kooperberg, Gudny Eiriksdottir, Rachel H. Mackey, Ani Manichaikul, Martin Farrall, Jennifer E. Huffman, Albert V. Smith, Vilmundur Gudnason, Aniruddh P. Patel, Ruth J. F. Loos, Sumeet A. Khetarpal, Daniel J. Rader, Domenico Girelli, Eric Boerwinkle, Qunyuan Zhang, Valeska Redon, Anuj Goel, Cornelia M. van Duijn, Bruce M. Psaty, Ruth McPherson, Piera Angelica Merlini, Daniel Levy, Ian J. Deary, Christopher J. O'Donnell, Kurt Lohman, Josyf C. Mychaleckyj, Brian W. Davis, Mary F. Feitosa, Kent D. Taylor, James S. Pankow, Marju Orho-Melander, Alanna C. Morrison, Igor Rudan, Alexander P. Reiner, William E. Kraus, Ulrike Peters, Paul L. Auer, Paolo Zanoni, Svati H. Shah, Olle Melander, Jennifer G. Robinson, Joshua C. Bis, Erwin P. Bottinger, Mingyao Li, George Hindy, Omri Gottesman, Stefano Duga, Herman A. Taylor, Y.-D. Ida Chen, David S. Siscovick, Aaron Isaacs, Michael Y. Tsai, Sekar Kathiresan, James G. Wilson, Pamela J. Schreiner, Nicola Martinelli, Myriam Fornage, Serkalem Demissie, Lenore J. Launer, Hugh Watkins, Arend Voorman, Jerome I. Rotter, Jeanette M. Stafford, John M. Starr, Gina M. Peloso, Rosanna Asselta, Gail Davies, Rebecca D. Jackson
Publikováno v:
American Journal of Human Genetics, 94(2), 223-232. Cell Press
American Journal of Human Genetics, 94(2), 223-32. Cell Press
American Journal of Human Genetics, 94(2), 223-32. Cell Press
Low-frequency coding DNA sequence variants in the proprotein convertase subtilisin/kexin type 9 gene (PCSK9) lower plasma low-density lipoprotein cholesterol (LDL-C), protect against risk of coronary heart disease (CHD), and have prompted the develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e58bcf3c1a5b72ab8d097dcaa1bd728d
https://doi.org/10.1016/j.ajhg.2014.01.009
https://doi.org/10.1016/j.ajhg.2014.01.009
Autor:
Jose M. Ordovas, Robert J. Straka, Ida Y.D. Chen, Stella Aslibekyan, Jerome I. Rotter, Degui Zhi, Skylar W. Marvel, Marguerite R. Irvin, John B. Buse, Steven A. Claas, Donna K. Arnett, Bertha Hidalgo, Vinodh Srinivasasainagendra, Michael J. Wagner, Daniel M. Rotroff, Xiuqing Guo, Alison A. Motsinger-Reif, Ingrid B. Borecki
Fibrates are commonly prescribed for hypertriglyceridemia, but they also lower LDL cholesterol and increase HDL cholesterol. Large interindividual variations in lipid response suggest that some patients may benefit more than others and genetic studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51bbdae09847be01c80822eec11056cc
Autor:
Richard N. Bergman, Markku S. Nieminen, Peter Vollenweider, André G. Uitterlinden, Luigi Ferrucci, Iris M. Heid, Lynda M. Rose, Brenda W.J.H. Penninx, Nicholas G. Martin, Joshua C. Bis, Aaron Isaacs, Jaspal S. Kooner, Gavin Lucas, Caroline Hayward, Masahiro Koseki, Andrew A. Hicks, Maja Barbalić, Marju Orho-Melander, Xueling Sim, James Scott, Manjinder S. Sandhu, Damien C. Croteau-Chonka, Andreas Ziegler, Wilmar Igi, Igor Rudan, Aki S. Havulinna, Leslie A. Lange, Hilma Holm, James G. Wilson, Albert V. Smith, Chiara Sabatti, Candace Guiducci, Paul Elliott, A. Cecile J.W. Janssens, Dorret I. Boomsma, Harry Campbell, Lee M. Kaplan, Ruth J. F. Loos, Robert Luben, Veikko Salomaa, Kyunga Kim, James F. Wilson, Mark Seielstad, Ben A. Oostra, Robert Y.L. Zee, Talin Haritunians, Stacey Gabriel, Michael Boehnke, Ida Surakka, Alex N. Parker, Serena Sanna, Fabio Marroni, Leif Groop, Ingrid B. Borecki, Weihua Zhang, John R. Thompson, Paul M. Ridker, James P. Pirruccello, Nicole Soranzo, Ulf Gyllensten, G. Kees Hovingh, Jian'an Luan, Wendy L. McArdle, Alistair S. Hall, Yurii S. Aulchenko, Thomas Meitinger, John Whitfield, Gonçalo R. Abecasis, Yii-Der Ida Chen, Tien Yin Wong, Deborah A. Nickerson, Jaakko Tuomilehto, Kijoung Song, Reijo Laaksonen, Jeanette Erdmann, Daniel J. Rader, Jing Hua Zhao, Irene Pichler, Robert A. Hegele, Marjo-Riitta Järvelin, Guillaume Paré, Juha Sinisalo, Andrew C. Edmondson, Peter P. Pramstaller, E-Shyong Tai, Vilmundur Gudnason, Linda S. Adair, Min Jin Go, Heather M. Stringham, Nancy L. Pedersen, Bruce M. Psaty, Åsa Johansson, Guillaume Lettre, Tamara B. Harris, Christian Gieger, Toby Johnson, Cornelia M. van Duijn, Samuli Ripatti, Johannes H. Smit, Sigrid W. Fouchier, Gonneke Willemsen, Mark J. Rieder, Nicholas D. Hastie, Leena Peltonen, Jacqueline C. M. Witteman, David Schlessinger, Kiran Musunuru, Eric Boerwinkle, Kay-Tee Khaw, Massimo Mangino, Themistocles L. Assimes, Claudia Langenberg, Yoon Shin Cho, Elena Gonzalez, Eric J.G. Sijbrands, Toshiko Tanaka, Inês Barroso, Vincent Mooser, Eco J. C. de Geus, Karen L. Mohlke, Jaakko Kaprio, Eric E. Schadt, Gudmar Thorleifsson, Nelson B. Freimer, H.-Erich Wichmann, Francis S. Collins, Grant W. Montgomery, John J.P. Kastelein, Inke R. Koenig, Xiuqing Guo, Ruth McPherson, Benjamin F. Voight, Stefania Bandinelli, Sally L. Ricketts, S. Matthijs Boekholdt, Xin Yuan, David Altshuler, Marja-Liisa Lokki, Lori L. Bonnycastle, Aimo Ruokonen, Noël P. Burtt, Unnur Thorsteinsdottir, Markus Perola, Edward G. Lakatta, Serkalem Demissie, Kenechi Ejebe, Muredach P. Reilly, Florian Kronenberg, Panagiotis Deloukas, Gabriel Crawford, Lenore J. Launer, David P. Strachan, Xiaohui Li, Christian Hengstenberg, Olle Melander, Juha Saharinen, Ulf de Faire, Joshua D. Smith, Heribert Schunkert, Thomas Quertermous, Young Jin Kim, Alan R. Tall, Anna F. Dominiczak, Nicholas J. Wareham, Robert Roberts, Mark J. Caulfield, Tanya M. Teslovich, Daniel I. Chasman, Manuela Uda, Jong-Young Lee, Erik Ingelsson, Christopher W. Kuzawa, Jerome I. Rotter, Gina M. Peloso, Christie M. Ballantyne, Mingyao Li, Alan F. Wright, Albert Hofman, Angelo Scuteri, Rick Twee-Hee Ong, L. Adrienne Cupples, Taesung Park, Veronique Vitart, Kaisa Silander, Jouke-Jan Hottenga, Kari Stefansson, Christopher J. O'Donnell, Mary F. Feitosa, Tim D. Spector, Mark I. McCarthy, Nilesh J. Samani, Christopher T. Johansen, David Masson, Cristian Pattaro, Ioannis M. Stylianou, Angela Doering, Patricia B. Munroe, Herman A. Taylor, Patrik K. E. Magnusson, John C. Chambers, Claudia Lamina, Sekar Kathiresan, Dawn M. Waterworth, Jose M. Ordovas, Alan B. Feranil, Cristen J. Willer, Kirsten Ohm Kyvik, Gérard Waeber, Ronald M. Krauss
Publikováno v:
Teslovich, T M, Musunuru, K, Smith, A V, Edmondson, A C, Stylianou, I M, Willemsen, G, Uitterlinden, A G, Penninx, B W J H, Montgomery, GW, Martin, N G, Hottenga, J J, de Geus, E J C, Boomsma, D I, van Duijn, C M, Peltonen, L, Abecasis, G R, Boehnke, M & Kathiresan, S 2010, ' Biological, clinical and population relevance of 95 loci for blood lipids ', Nature, vol. 466, no. 7307, pp. 707-713 . https://doi.org/10.1038/nature09270
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Nature, 466(7307), 707-713. Nature Publishing Group
Nature
Nature; Vol 466
Teslovich, T M, Musunuru, K, Smith, A V, Edmondson, A C, Stylianou, I M, Koseki, M, Pirruccello, J P, Ripatti, S, Chasman, D I, Willer, C J, Johansen, C T, Fouchier, S W, Isaacs, A, Peloso, G M, Barbalic, M, Ricketts, S L, Bis, J C, Aulchenko, Y S, Thorleifsson, G, Feitosa, M F, Chambers, J, Orho-Melander, M, Melander, O, Johnson, T, Li, X, Guo, X, Li, M, Cho, Y S, Go, M J, Kim, Y J, Lee, J-Y, Park, T, Kim, K, Sim, X, Ong, R T-H, Croteau-Chonka, D C, Lange, L A, Smith, J D, Song, K, Zhao, J H, Yuan, X, Luan, J, Lamina, C, Ziegler, A, Zhang, W, Zee, R Y L, Wright, A, Witteman, J C M, Wilson, J, Willemsen, G, Wichmann, H-E, Whitfield, J B, Waterworth, D M, Wareham, N J, Waeber, G, Vollenweider, P, Voight, B F, Vitart, V, Uitterlinden, A G, Uda, M, Tuomilehto, J, Thompson, J R, Tanaka, T, Surakka, I, Stringham, H M, Spector, T D, Soranzo, N, Smit, J H, Sinisalo, J, Silander, K, Sijbrands, E J G, Scuteri, A, Scott, J, Schlessinger, D, Sanna, S, Salomaa, V, Saharinen, J, Sabatti, C, Ruokonen, A, Rudan, I, Rose, L M, Roberts, R, Rieder, M, Psaty, B M, Pramstaller, P P, Pichler, I, Perola, M, Penninx, B W J H, Pedersen, N L, Pattaro, C, Parker, A N, Pare, G, Oostra, B A, O'Donnell, C J, Nieminen, M S, Nickerson, D A, Montgomery, G W, Meitinger, T, McPherson, R, McCarthy, M I, McArdle, W, Masson, D, Martin, N G, Marroni, F, Mangino, M, Magnusson, P K E, Lucas, G, Luben, R, Loos, R J F, Lokki, M-L, Lettre, G, Langenberg, C, Launer, L J, Lakatta, E G, Laaksonen, R, Kyvik, K O, Kronenberg, F, Koenig, I R, Khaw, K-T, Kaprio, J, Kaplan, L M, Johansson, A, Jarvelin, M-R, Janssens, A C J W, Ingelsson, E, Igi, W, Hovingh, G K, Hottenga, J-J, Hofman, A, Hicks, A A, Hengstenberg, C, Heid, I M, Hayward, C, Havulinna, A S, Hastie, N, Harris, T B, Haritunians, T, Hall, A S, Gyllensten, U, Guiducci, C, Groop, L C, Gonzalez, E, Gieger, C, Freimer, N B, Ferrucci, L, Erdmann, J, Elliott, P, Ejebe, K G, Doering, A, Dominiczak, A F, Demissie, S, Deloukas, P, de Geus, E J C, de Faire, U, Crawford, G, Collins, F S, Chen, Y I, Caulfield, M J, Campbell, H, Burtt, N P, Bonnycastle, L L, Boomsma, D I, Boekholdt, S M, Bergman, R N, Barroso, I, Bandinelli, S, Ballantyne, C M, Assimes, T L, Quertermous, T, Altshuler, D, Seielstad, M, Wong, T Y, Tai, E-S, Feranil, A B, Kuzawa, C W, Adair, L S, Taylor, H A, Borecki, I B, Gabriel, S B, Wilson, J G, Holm, H, Thorsteinsdottir, U, Gudnason, V, Krauss, R M, Mohlke, K L, Ordovas, J M, Munroe, P B, Kooner, J S, Tall, A R, Hegele, R A, Kastelein, J J P, Schadt, E E, Rotter, J I, Boerwinkle, E, Strachan, D P, Mooser, V, Stefansson, K, Reilly, M P, Samani, N J, Schunkert, H, Cupples, L A, Sandhu, M S, Ridker, P M, Rader, D J, van Duijn, C M, Peltonen, L, Abecasis, G R, Boehnke, M & Kathiresan, S 2010, ' Biological, clinical and population relevance of 95 loci for blood lipids ', Nature, vol. 466, no. 7307, pp. 707-713 . https://doi.org/10.1038/nature09270
Teslovich, T M, Musunuru, K, Smith, A V, Edmondson, A C, Stylianou, I M, Koseki, M, Pirruccello, J P, Ripatti, S, Chasman, D I, Willer, C J, Johansen, C T, Fouchier, S W, Isaacs, A, Peloso, G M, Barbalic, M, Ricketts, S L, Bis, J C, Aulchenko, Y S, Thorleifsson, G, Feitosa, M F, Chambers, J, Orho-Melander, M, Melander, O, Johnson, T, Li, X, Guo, X, Li, M, Shin Cho, Y, Jin Go, M, Jin Kim, Y, Lee, J-Y, Park, T, Kim, K, Sim, X, Twee-Hee Ong, R, Croteau-Chonka, D C, Lange, L A, Smith, J D, Song, K, Hua Zhao, J, Yuan, X, Luan, J, Lamina, C, Ziegler, A, Zhang, W, Zee, R Y L, Wright, A F, Witteman, J C M, Wilson, J F, Willemsen, G, Wichmann, H-E, Whitfield, J B, Waterworth, D M, Wareham, N J, Waeber, G, Vollenweider, P, Voight, B F, Vitart, V, Uitterlinden, A G, Uda, M, Tuomilehto, J, Thompson, J R, Tanaka, T, Surakka, I, Stringham, H M, Spector, T D, Soranzo, N, Smit, J H, Sinisalo, J, Silander, K, Sijbrands, E J G, Scuteri, A, Scott, J, Schlessinger, D, Sanna, S, Salomaa, V, Saharinen, J, Sabatti, C, Ruokonen, A, Rudan, I, Rose, L M, Roberts, R, Rieder, M, Psaty, B M, Pramstaller, P P, Pichler, I, Perola, M, Penninx, B W J H, Pedersen, N L, Pattaro, C, Parker, A N, Pare, G, Oostra, B A, O'Donnell, C J, Nieminen, M S, Nickerson, D A, Montgomery, G W, Meitinger, T, McPherson, R, McCarthy, M I, McArdle, W, Masson, D, Martin, N G, Marroni, F, Mangino, M, Magnusson, P K E, Lucas, G, Luben, R, Loos, R J F, Lokki, M-L, Lettre, G, Langenberg, C, Launer, L J, Lakatta, E G, Laaksonen, R, Kyvik, K O, Kronenberg, F, König, I R, Khaw, K-T, Kaprio, J, Kaplan, L M, Johansson, A, Jarvelin, M-R, Janssens, A C J W, Ingelsson, E, Igl, W, Kees Hovingh, G, Hottenga, J-J, Hofman, A, Hicks, A A, Hengstenberg, C, Heid, I M, Hayward, C, Havulinna, A S, Hastie, N D, Harris, T B, Haritunians, T, Hall, A S, Gyllensten, U, Guiducci, C, Groop, L C, Gonzalez, E, Gieger, C, Freimer, N B, Ferrucci, L, Erdmann, J, Elliott, P, Ejebe, K G, Döring, A, Dominiczak, A F, Demissie, S, Deloukas, P, de Geus, E J C, de Faire, U, Crawford, G, Collins, F S, Chen, Y I, Caulfield, M J, Campbell, H, Burtt, N P, Bonnycastle, L L, Boomsma, D I, Boekholdt, S M, Bergman, R N, Barroso, I, Bandinelli, S, Ballantyne, C M, Assimes, T L, Quertermous, T, Altshuler, D, Seielstad, M, Wong, T Y, Tai, E-S, Feranil, A B, Kuzawa, C W, Adair, L S, Taylor, H A, Borecki, I B, Gabriel, S B, Wilson, J G, Holm, H, Thorsteinsdottir, U, Gudnason, V, Krauss, R M, Mohlke, K L, Ordovas, J M, Munroe, P B, Kooner, J S, Tall, A R, Hegele, R A, Kastelein, J J P, Schadt, E E, Rotter, J I, Boerwinkle, E, Strachan, D P, Mooser, V, Stefansson, K, Reilly, M P, Samani, N J, Schunkert, H, Cupples, L A, Sandhu, M S, Ridker, P M, Rader, D J, van Duijn, C M, Peltonen, L, Abecasis, G R, Boehnke, M & Kathiresan, S 2010, ' Biological, clinical and population relevance of 95 loci for blood lipids ', Nature, vol. 466, no. 7307, pp. 707-13 . https://doi.org/10.1038/nature09270
Nature, 466(7307), 707-713. Nature Publishing Group
Nature
Nature; Vol 466
Teslovich, T M, Musunuru, K, Smith, A V, Edmondson, A C, Stylianou, I M, Koseki, M, Pirruccello, J P, Ripatti, S, Chasman, D I, Willer, C J, Johansen, C T, Fouchier, S W, Isaacs, A, Peloso, G M, Barbalic, M, Ricketts, S L, Bis, J C, Aulchenko, Y S, Thorleifsson, G, Feitosa, M F, Chambers, J, Orho-Melander, M, Melander, O, Johnson, T, Li, X, Guo, X, Li, M, Cho, Y S, Go, M J, Kim, Y J, Lee, J-Y, Park, T, Kim, K, Sim, X, Ong, R T-H, Croteau-Chonka, D C, Lange, L A, Smith, J D, Song, K, Zhao, J H, Yuan, X, Luan, J, Lamina, C, Ziegler, A, Zhang, W, Zee, R Y L, Wright, A, Witteman, J C M, Wilson, J, Willemsen, G, Wichmann, H-E, Whitfield, J B, Waterworth, D M, Wareham, N J, Waeber, G, Vollenweider, P, Voight, B F, Vitart, V, Uitterlinden, A G, Uda, M, Tuomilehto, J, Thompson, J R, Tanaka, T, Surakka, I, Stringham, H M, Spector, T D, Soranzo, N, Smit, J H, Sinisalo, J, Silander, K, Sijbrands, E J G, Scuteri, A, Scott, J, Schlessinger, D, Sanna, S, Salomaa, V, Saharinen, J, Sabatti, C, Ruokonen, A, Rudan, I, Rose, L M, Roberts, R, Rieder, M, Psaty, B M, Pramstaller, P P, Pichler, I, Perola, M, Penninx, B W J H, Pedersen, N L, Pattaro, C, Parker, A N, Pare, G, Oostra, B A, O'Donnell, C J, Nieminen, M S, Nickerson, D A, Montgomery, G W, Meitinger, T, McPherson, R, McCarthy, M I, McArdle, W, Masson, D, Martin, N G, Marroni, F, Mangino, M, Magnusson, P K E, Lucas, G, Luben, R, Loos, R J F, Lokki, M-L, Lettre, G, Langenberg, C, Launer, L J, Lakatta, E G, Laaksonen, R, Kyvik, K O, Kronenberg, F, Koenig, I R, Khaw, K-T, Kaprio, J, Kaplan, L M, Johansson, A, Jarvelin, M-R, Janssens, A C J W, Ingelsson, E, Igi, W, Hovingh, G K, Hottenga, J-J, Hofman, A, Hicks, A A, Hengstenberg, C, Heid, I M, Hayward, C, Havulinna, A S, Hastie, N, Harris, T B, Haritunians, T, Hall, A S, Gyllensten, U, Guiducci, C, Groop, L C, Gonzalez, E, Gieger, C, Freimer, N B, Ferrucci, L, Erdmann, J, Elliott, P, Ejebe, K G, Doering, A, Dominiczak, A F, Demissie, S, Deloukas, P, de Geus, E J C, de Faire, U, Crawford, G, Collins, F S, Chen, Y I, Caulfield, M J, Campbell, H, Burtt, N P, Bonnycastle, L L, Boomsma, D I, Boekholdt, S M, Bergman, R N, Barroso, I, Bandinelli, S, Ballantyne, C M, Assimes, T L, Quertermous, T, Altshuler, D, Seielstad, M, Wong, T Y, Tai, E-S, Feranil, A B, Kuzawa, C W, Adair, L S, Taylor, H A, Borecki, I B, Gabriel, S B, Wilson, J G, Holm, H, Thorsteinsdottir, U, Gudnason, V, Krauss, R M, Mohlke, K L, Ordovas, J M, Munroe, P B, Kooner, J S, Tall, A R, Hegele, R A, Kastelein, J J P, Schadt, E E, Rotter, J I, Boerwinkle, E, Strachan, D P, Mooser, V, Stefansson, K, Reilly, M P, Samani, N J, Schunkert, H, Cupples, L A, Sandhu, M S, Ridker, P M, Rader, D J, van Duijn, C M, Peltonen, L, Abecasis, G R, Boehnke, M & Kathiresan, S 2010, ' Biological, clinical and population relevance of 95 loci for blood lipids ', Nature, vol. 466, no. 7307, pp. 707-713 . https://doi.org/10.1038/nature09270
Plasma concentrations of total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and triglycerides are among the most important risk factors for coronary artery disease (CAD) and are targets for therapeutic interv
Autor:
Tuomo Rankinen, James S. Skinner, Mary F. Feitosa, Jean-Pierre Després, Michael A. Province, Yvon C. Chagnon, Claude Bouchard, Jack H. Wilmore, Arthur S. Leon, Treva Rice, Jacques Gagnon, D. C. Rao, Ingrid B. Borecki
Publikováno v:
Atherosclerosis. 182:349-360
Fasting triglyceride (TG) levels in total plasma and in lipoprotein subfractions were assessed both at baseline and after a 20-week exercise training intervention in 99 White and 101 Black families. A genome-wide multipoint variance component linkage
Autor:
Jacques Gagnon, Ping An, Tuomo Rankinen, Olavi Ukkola, Roland Rosmond, James S. Skinner, Treva Rice, Dabeeru C. Rao, Arthur S. Leon, Ingrid B. Borecki, Jack H. Wilmore, Claude Bouchard
Publikováno v:
Metabolism. 50:1315-1322
A genome-wide linkage scan was performed to identify genomic regions that influence levels of dehydroepiandrosterone (DHEA), DHEA sulfate (DHEAS), and DHEA fatty acid esters (DHEA-FA) at baseline and in response to 20 weeks of endurance exercise trai
Autor:
Jacqueline C.M. Witteman, Nicole Probst-Hensch, Gail Davies, Anna Köttgen, Qunyuan Zhang, Pio D'Adamo, Nicholas G. Martin, Silvia Tore, Stephan J. L. Bakker, Gian Andri Thun, Cinzia Sala, Peter P. Pramstaller, Tamara B. Harris, Aaron Isaacs, Sheila Ulivi, Rossella Sorice, Xuan Liu, Andrew A. Hicks, Henry Völzke, Daniela Ruggiero, Arnold von Eckardstein, Yukinori Okada, Andres Metspalu, Jeffrey Metter, Serena Sanna, Jennifer E. Huffman, Philipp S. Wild, Florian Ernst, Eva Albrecht, Mary F. Feitosa, Claudia Schurmann, Kathrin Budde, Veikko Salomaa, Darina Czamara, Elizabeth G. Holliday, Marcel Bruinenberg, Laura Portas, Maris Laan, Alan J. Gow, Caroline Hayward, Tim D. Spector, Ozren Polasek, Ilja M. Nolte, Rodney J. Scott, Massimo Mangino, David S. Siscovick, Nilesh J. Samani, Toomas Haller, Laura Frogheri, A. Jula, Mika Kähönen, Bruce H. R. Wolffenbuttel, Caroline S. Fox, David R. Jacobs, Julia Shi, Yusuke Nakamura, Daniel I. Chasman, Fabian J. Theis, Alan F. Wright, Ayse Demirkan, Francesco Cucca, Paolo Gasparini, Paul M. Ridker, Olli T. Raitakari, Daniela Toniolo, Maristella Steri, Mario Pirastu, Susan Campbell, Maksim Struchalin, So-Youn Shin, Mark J. Caulfield, H.-Erich Wichmann, Grant W. Montgomery, Åsa Johansson, Alexander Teumer, Ulf Gyllensten, Robert M. Plenge, Michel Burnier, Michael Schallert, Jan Krumsiek, Jing Hua Zhao, Andres Salumets, Poorva Mudgal, Anke Tönjes, James F. Meschia, Gauti Kjartan Gislason, Perttu Salo, Angela Döring, Afshin Parsa, Vilmundur Gudnason, Patrick F. McArdle, Rita P. S. Middelberg, W. H. Linda Kao, Aldi Kraja, Christopher Oldmeadow, Adrienne Tin, Loic Yengo, Murielle Bochud, Gerjan Navis, Christian Gieger, Toshiko Tanaka, Cornelia M. van Duijn, Samuli Ripatti, Terho Lehtimäki, Claudia Langenberg, Bernhard O. Boehm, Conall M. O'Seaghdha, Eric Boerwinkle, Nicole Soranzo, Tõnu Esko, Susan M. Farrington, Mike A. Nalls, John F. Peden, Hyon K. Choi, Anuj Goel, Andrew D. Johnson, Norman Klopp, Anne Grotevendt, Halit Ongen, Marcus E. Kleber, Myriam Fornage, Malcolm G. Dunlop, Igor Rudan, Federico Murgia, Beverley Balkau, Jorma Viikari, Christopher P. Nelson, Gérard Waeber, Lenore J. Launer, Ivana Persico, Inga Prokopenko, Guo Li, Tatijana Zemunik, Elisabetta Trabetti, Tanja Zeller, Hugh Watkins, Qiong Yang, James F. Wilson, Peter Vollenweider, Veronique Vitart, Markus Perola, Nicola Pirastu, Olivier Devuyst, Irene Mateo Leach, John Attia, Bruce M. Psaty, Nicholas J. Wareham, Susanne Lucae, Josef Coresh, Ingrid B. Borecki, Claudia Hundertmark, Weihua Zhang, Luigi Ferrucci, Jaspal S. Kooner, Stefan Kloiber, Lynda M. Rose, Naoyuki Kamatani, Zoltán Kutalik, Giovanni Malerba, Ian J. Deary, Albert V. Smith, Helena Schmidt, Eva Lattka, Philippe Froguel, Harry Campbell, Medea Imboden, Antonio Lupo, Angelo L. Gaffo, Vasiliki Lagou, Alan R. Shuldiner, John Whitfield, Abbas Dehghan, Winfried März, Elin Org, Albert Hofman, Margus Viigimaa, Konstantin Strauch, Toshihiro Tanaka, Andrew B. Singleton, Stefania Bandinelli, Christian Hengstenberg, Xinzhong Li, Wiek H. van Gilst, Pim van der Harst, Giorgio Pistis, Jerome I. Rotter, Maria Grazia Piras, Gary C. Curhan, Brenda W.J.H. Penninx, Ramaiah Nagaraja, Nabila Bouatia-Naji, Christian Müller, Ronald P. Stolk, Pau Navarro, Lorna M. Lopez, Ruth J. F. Loos, Albert Tenesa, Johannes H. Smit, Peter Kraft, Giovanni Gambaro, Sarah H. Wild, Patricia B. Munroe, André G. Uitterlinden, Ivana Kolcic, Bernhard R. Winkelmann, Pankaj Sharma, John C. Chambers, Nicholas D. Hastie, Matthias Nauck, Harold Snieder, Michael Stumvoll, Reinhold Schmidt, Hans L. Hillege, Kiang Liu, Fernando Rivadeneira, Owen M. Woodward, Morris J. Brown, Margus Putku, Sabine Schipf, Mirna Kirin, Kay-Tee Khaw, Melanie Waldenberger, Evropi Theodoratou, Marina Ciullo, Michiaki Kubo
Publikováno v:
Nature Genetics, 45(2), 145-154. Nature Publishing Group
Nature Genetics
Nature Genetics, 45(2), 145-54. Nature Publishing Group
Kottgen, A, Albrecht, E, Teumer, A, Vitart, V, Krumsiek, J, Hundertmark, C, Pistis, G, Ruggiero, D, O'Seaghdha, C M, Haller, T, Yang, Q, Johnson, A D, Kutalik, Z, Smith, A V, Shi, J L, Struchalin, M, Middelberg, R P S, Brown, M J, Gaffo, A L, Pirastu, N, Li, G, Hayward, C, Zemunik, T, Huffman, J, Yengo, L, Zhao, J H, Demirkan, A, Feitosa, M F, Liu, X, Malerba, G, Lopez, L M, van der Harst, P, Li, X Z, Kleber, M E, Hicks, A A, Nolte, I M, Johansson, A, Murgia, F, Wild, S H, Bakker, S J L, Peden, J F, Dehghan, A, Steri, M, Tenesa, A, Lagou, V, Salo, P, Mangino, M, Rose, L M, Lehtimaki, T, Woodward, O M, Okada, Y, Tin, A, Muller, C, Oldmeadow, C, Putku, M, Czamara, D, Kraft, P, Frogheri, L, Thun, G A, Grotevendt, A, Gislason, G K, Harris, T B, Launer, L J, McArdle, P, Shuldiner, A R, Boerwinkle, E, Coresh, J, Schmidt, H, Schallert, M, Martin, N G, Montgomery, G W, Kubo, M, Nakamura, Y, Tanaka, T, Munroe, P B, Samani, N J, Jacobs, D R, Liu, K, d'Adamo, P, Ulivi, S, Rotter, J I, Psaty, B M, Vollenweider, P, Waeber, G, Campbell, S, Devuyst, O, Navarro, P, Kolcic, I, Hastie, N, Balkau, B, Froguel, P, Esko, T, Salumets, A, Khaw, K T, Langenberg, C, Wareham, N J, Isaacs, A, Kraja, A, Zhang, Q Y, Penninx, B W J H, Smit, J H, Bochud, M & Gieger, C 2013, ' Genome-wide association analyses identify 18 new loci associated with serum urate concentrations ', Nature Genetics, vol. 45, no. 2, pp. 145-154 . https://doi.org/10.1038/ng.2500
Köttgen, A, Albrecht, E, Teumer, A, Vitart, V, Krumsiek, J, Hundertmark, C, Pistis, G, Ruggiero, D, O'Seaghdha, C M, Haller, T, Yang, Q, Tanaka, T, Johnson, A D, Kutalik, Z, Smith, A V, Shi, J, Struchalin, M, Middelberg, R P S, Brown, M J, Gaffo, A L, Pirastu, N, Li, G, Hayward, C, Zemunik, T, Huffman, J, Yengo, L, Zhao, J H, Demirkan, A, Feitosa, M F, Liu, X, Malerba, G, Lopez, L M, van der Harst, P, Li, X, Kleber, M E, Wild, S H, Tenesa, A, Navarro, P, Hastie, N, Davies, G, Gow, A J, Wilson, J F, Farrington, S M, Theodoratou, E, Polasek, O, Campbell, H, Rudan, I, Deary, I J & Wright, A F & Dunlop, M G 2013, ' Genome-wide association analyses identify 18 new loci associated with serum urate concentrations ', Nature Genetics, vol. 45, no. 2, pp. 145-154 . https://doi.org/10.1038/ng.2500
Nature genetics
(2013). doi:10.1038/ng.2500
info:cnr-pdr/source/autori:Köttgen A, Albrecht E, Teumer A, Vitart V, Krumsiek J, Hundertmark C, Pistis G, Ruggiero D, O'Seaghdha CM, Haller T, Yang Q, Tanaka T, Johnson AD, Kutalik Z, Smith AV, Shi J, Struchalin M, Middelberg RP, Brown MJ, Gaffo AL, Pirastu N, Li G, Hayward C, Zemunik T, Huffman J, Yengo L, Zhao JH, Demirkan A, Feitosa MF, Liu X, Malerba G, Lopez LM, van der Harst P, Li X, Kleber ME, Hicks AA, Nolte IM, Johansson A, Murgia F, Wild SH, Bakker SJ, Peden JF, Dehghan A, Steri M, Tenesa A, Lagou V, Salo P, Mangino M, Rose LM, Lehtimäki T, Woodward OM, Okada Y, Tin A, Müller C, Oldmeadow C, Putku M, Czamara D, Kraft P, Frogheri L, Thun GA, Grotevendt A, Gislason GK, Harris TB, Launer LJ, McArdle P, Shuldiner AR, Boerwinkle E, Coresh J, Schmidt H, Schallert M, Martin NG, Montgomery GW, Kubo M, Nakamura Y, Tanaka T, Munroe PB, Samani NJ, Jacobs DR Jr, Liu K, D'Adamo P, Ulivi S, Rotter JI, Psaty BM, Vollenweider P, Waeber G, Campbell S, Devuyst O, Navarro P, Kolcic I, Hastie N, Balkau B, Froguel P, Esko T, Salumets A, Khaw KT, Langenberg C, Wareham NJ, Isaacs A, Kraja A, Zhang Q, Wild PS, Scott RJ, Holliday EG, Org E, Viigimaa M, Bandinelli S, Metter JE, Lupo A, Trabetti E, Sorice R, Döring A, Lattka E, Strauch K, Theis F, Waldenberger M, Wichmann HE, Davies G, Gow AJ, Bruinenberg M; LifeLines Cohort Study, Stolk RP, Kooner JS, Zhang W, Winkelmann BR, Boehm BO, Lucae S, Penninx BW, Smit JH, Curhan G, Mudgal P, Plenge RM, Portas L, Persico I, Kirin M, Wilson JF, Mateo Leach I, van Gilst WH, Goel A, Ongen H, Hofman A, Rivadeneira F, Uitterlinden AG, Imboden M, von Eckardstein A, Cucca F, Nagaraja R, Piras MG, Nauck M, Schurmann C, Budde K, Ernst F, Farrington SM, Theodoratou E, Prokopenko I, Stumvoll M, Jula A, Perola M, Salomaa V, Shin SY, Spector TD, Sala C, Ridker PM, Kähönen M, Viikari J, Hengstenberg C, Nelson CP; CARDIoGRAM Consortium; DIAGRAM Consortium; ICBP Consortium; MAGIC Consortium, Meschia JF, Nalls MA, Sharma P, Singleton AB, Kamatani N, Zeller T, Burnier M, Attia J, Laan M, Klopp N, Hillege HL, Kloiber S, Choi H, Pirastu M, Tore S, Probst-Hensch NM, Völzke H, Gudnason V, Parsa A, Schmidt R, Whitfield JB, Fornage M, Gasparini P, Siscovick DS, Pola?ek O, Campbell H, Rudan I, Bouatia-Naji N, Metspalu A, Loos RJ, van Duijn CM, Borecki IB, Ferrucci L, Gambaro G, Deary IJ, Wolffenbuttel BH, Chambers JC, März W, Pramstaller PP, Snieder H, Gyllensten U, Wright AF, Navis G, Watkins H, Witteman JC, Sanna S, Schipf S, Dunlop MG, Tönjes A, Ripatti S, Soranzo N, Toniolo D, Chasman DI, Raitakari O, Kao WH, Ciullo M, Fox CS, Caulfield M, Bochud M, Gieger C./titolo:Genome-wide association analyses identify 18 new loci associated with serum urate concentrations/doi:10.1038%2Fng.2500/rivista:Nature genetics (Print)/anno:2013/pagina_da:/pagina_a:/intervallo_pagine:/volume
Nature Genetics; Vol 45
Nature Genetics, vol. 45, no. 2, pp. 145-154
Human Genetics, 45(2):145, 154-11. Springer-Verlag
Nature Genetics
Nature Genetics, 45(2), 145-54. Nature Publishing Group
Kottgen, A, Albrecht, E, Teumer, A, Vitart, V, Krumsiek, J, Hundertmark, C, Pistis, G, Ruggiero, D, O'Seaghdha, C M, Haller, T, Yang, Q, Johnson, A D, Kutalik, Z, Smith, A V, Shi, J L, Struchalin, M, Middelberg, R P S, Brown, M J, Gaffo, A L, Pirastu, N, Li, G, Hayward, C, Zemunik, T, Huffman, J, Yengo, L, Zhao, J H, Demirkan, A, Feitosa, M F, Liu, X, Malerba, G, Lopez, L M, van der Harst, P, Li, X Z, Kleber, M E, Hicks, A A, Nolte, I M, Johansson, A, Murgia, F, Wild, S H, Bakker, S J L, Peden, J F, Dehghan, A, Steri, M, Tenesa, A, Lagou, V, Salo, P, Mangino, M, Rose, L M, Lehtimaki, T, Woodward, O M, Okada, Y, Tin, A, Muller, C, Oldmeadow, C, Putku, M, Czamara, D, Kraft, P, Frogheri, L, Thun, G A, Grotevendt, A, Gislason, G K, Harris, T B, Launer, L J, McArdle, P, Shuldiner, A R, Boerwinkle, E, Coresh, J, Schmidt, H, Schallert, M, Martin, N G, Montgomery, G W, Kubo, M, Nakamura, Y, Tanaka, T, Munroe, P B, Samani, N J, Jacobs, D R, Liu, K, d'Adamo, P, Ulivi, S, Rotter, J I, Psaty, B M, Vollenweider, P, Waeber, G, Campbell, S, Devuyst, O, Navarro, P, Kolcic, I, Hastie, N, Balkau, B, Froguel, P, Esko, T, Salumets, A, Khaw, K T, Langenberg, C, Wareham, N J, Isaacs, A, Kraja, A, Zhang, Q Y, Penninx, B W J H, Smit, J H, Bochud, M & Gieger, C 2013, ' Genome-wide association analyses identify 18 new loci associated with serum urate concentrations ', Nature Genetics, vol. 45, no. 2, pp. 145-154 . https://doi.org/10.1038/ng.2500
Köttgen, A, Albrecht, E, Teumer, A, Vitart, V, Krumsiek, J, Hundertmark, C, Pistis, G, Ruggiero, D, O'Seaghdha, C M, Haller, T, Yang, Q, Tanaka, T, Johnson, A D, Kutalik, Z, Smith, A V, Shi, J, Struchalin, M, Middelberg, R P S, Brown, M J, Gaffo, A L, Pirastu, N, Li, G, Hayward, C, Zemunik, T, Huffman, J, Yengo, L, Zhao, J H, Demirkan, A, Feitosa, M F, Liu, X, Malerba, G, Lopez, L M, van der Harst, P, Li, X, Kleber, M E, Wild, S H, Tenesa, A, Navarro, P, Hastie, N, Davies, G, Gow, A J, Wilson, J F, Farrington, S M, Theodoratou, E, Polasek, O, Campbell, H, Rudan, I, Deary, I J & Wright, A F & Dunlop, M G 2013, ' Genome-wide association analyses identify 18 new loci associated with serum urate concentrations ', Nature Genetics, vol. 45, no. 2, pp. 145-154 . https://doi.org/10.1038/ng.2500
Nature genetics
(2013). doi:10.1038/ng.2500
info:cnr-pdr/source/autori:Köttgen A, Albrecht E, Teumer A, Vitart V, Krumsiek J, Hundertmark C, Pistis G, Ruggiero D, O'Seaghdha CM, Haller T, Yang Q, Tanaka T, Johnson AD, Kutalik Z, Smith AV, Shi J, Struchalin M, Middelberg RP, Brown MJ, Gaffo AL, Pirastu N, Li G, Hayward C, Zemunik T, Huffman J, Yengo L, Zhao JH, Demirkan A, Feitosa MF, Liu X, Malerba G, Lopez LM, van der Harst P, Li X, Kleber ME, Hicks AA, Nolte IM, Johansson A, Murgia F, Wild SH, Bakker SJ, Peden JF, Dehghan A, Steri M, Tenesa A, Lagou V, Salo P, Mangino M, Rose LM, Lehtimäki T, Woodward OM, Okada Y, Tin A, Müller C, Oldmeadow C, Putku M, Czamara D, Kraft P, Frogheri L, Thun GA, Grotevendt A, Gislason GK, Harris TB, Launer LJ, McArdle P, Shuldiner AR, Boerwinkle E, Coresh J, Schmidt H, Schallert M, Martin NG, Montgomery GW, Kubo M, Nakamura Y, Tanaka T, Munroe PB, Samani NJ, Jacobs DR Jr, Liu K, D'Adamo P, Ulivi S, Rotter JI, Psaty BM, Vollenweider P, Waeber G, Campbell S, Devuyst O, Navarro P, Kolcic I, Hastie N, Balkau B, Froguel P, Esko T, Salumets A, Khaw KT, Langenberg C, Wareham NJ, Isaacs A, Kraja A, Zhang Q, Wild PS, Scott RJ, Holliday EG, Org E, Viigimaa M, Bandinelli S, Metter JE, Lupo A, Trabetti E, Sorice R, Döring A, Lattka E, Strauch K, Theis F, Waldenberger M, Wichmann HE, Davies G, Gow AJ, Bruinenberg M; LifeLines Cohort Study, Stolk RP, Kooner JS, Zhang W, Winkelmann BR, Boehm BO, Lucae S, Penninx BW, Smit JH, Curhan G, Mudgal P, Plenge RM, Portas L, Persico I, Kirin M, Wilson JF, Mateo Leach I, van Gilst WH, Goel A, Ongen H, Hofman A, Rivadeneira F, Uitterlinden AG, Imboden M, von Eckardstein A, Cucca F, Nagaraja R, Piras MG, Nauck M, Schurmann C, Budde K, Ernst F, Farrington SM, Theodoratou E, Prokopenko I, Stumvoll M, Jula A, Perola M, Salomaa V, Shin SY, Spector TD, Sala C, Ridker PM, Kähönen M, Viikari J, Hengstenberg C, Nelson CP; CARDIoGRAM Consortium; DIAGRAM Consortium; ICBP Consortium; MAGIC Consortium, Meschia JF, Nalls MA, Sharma P, Singleton AB, Kamatani N, Zeller T, Burnier M, Attia J, Laan M, Klopp N, Hillege HL, Kloiber S, Choi H, Pirastu M, Tore S, Probst-Hensch NM, Völzke H, Gudnason V, Parsa A, Schmidt R, Whitfield JB, Fornage M, Gasparini P, Siscovick DS, Pola?ek O, Campbell H, Rudan I, Bouatia-Naji N, Metspalu A, Loos RJ, van Duijn CM, Borecki IB, Ferrucci L, Gambaro G, Deary IJ, Wolffenbuttel BH, Chambers JC, März W, Pramstaller PP, Snieder H, Gyllensten U, Wright AF, Navis G, Watkins H, Witteman JC, Sanna S, Schipf S, Dunlop MG, Tönjes A, Ripatti S, Soranzo N, Toniolo D, Chasman DI, Raitakari O, Kao WH, Ciullo M, Fox CS, Caulfield M, Bochud M, Gieger C./titolo:Genome-wide association analyses identify 18 new loci associated with serum urate concentrations/doi:10.1038%2Fng.2500/rivista:Nature genetics (Print)/anno:2013/pagina_da:/pagina_a:/intervallo_pagine:/volume
Nature Genetics; Vol 45
Nature Genetics, vol. 45, no. 2, pp. 145-154
Human Genetics, 45(2):145, 154-11. Springer-Verlag
Elevated serum urate concentrations can cause gout, a prevalent and painful inflammatory arthritis. By combining data from >140,000 individuals of European ancestry within the Global Urate Genetics Consortium (GUGC), we identified and replicated 28 g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc47fb35390519f51b5ff7c2f271262b
https://www.bib.irb.hr/639277
https://www.bib.irb.hr/639277
Autor:
Treva Rice, Tuomo Rankinen, Ingrid B. Borecki, Mary F. Feitosa, John Blangero, James S. Skinner, D. C. Rao, Jean-Pierre Després, Arthur S. Leon, Claude Bouchard
Publikováno v:
Scopus-Elsevier
To determine whether a common quantitative trait locus (QTL) influences the variation of fasting triglyceride (TG) and high-density lipoprotein cholesterol (HDL-C) levels, we used a bivariate multipoint linkage analysis with 654 polymorphic markers i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7185dc1b5660a25bf3442c791ae9310c
http://www.scopus.com/inward/record.url?eid=2-s2.0-33845569867&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-33845569867&partnerID=MN8TOARS