Zobrazeno 1 - 10
of 173
pro vyhledávání: '"Li, Wei"'
Autor:
Zhou Liang, Wang Run-ling, Yang Wenyu, Du Shan, Wu JingWei, Li LiPeng, Ma Ying, Li Wei-Ya, Ma Yang-Chun
Publikováno v:
Molecular Diversity. 26:1567-1580
SHP2 is a protein tyrosine phosphatase (PTP) that can regulate the tyrosine phosphorylation level. Overexpression of SHP2 will promote the development of cancer diseases, so SHP2 has become one of the popular targets for the treatment of cancer. Stud
Publikováno v:
The Journal of Organic Chemistry. 86:9861-9868
A direct enaminone C-N bond coupling functionalization that generates a new C-P bond using dialkyl phosphonate for the efficient and stereoselective synthesis of (E)-alkenylphosphonates is reported. The reactions toward target products proceed well w
Publikováno v:
Journal of Natural Products. 84:1022-1033
The discovery of efficient and specific HIV-latency-reversing agents is critical for HIV therapy. Here, we developed wikstroelide E, a daphnane diterpene from the buds of Wikstroemia chamaedaphne, as a potential HIV-latency-reversing agent that is 25
Autor:
Xiao-Qing Guan, Yi-Shu Zhao, Xiaoze Bao, Li-Wei Zou, Yang Yang, Xing-Kai Qian, Hong Wang, Pei-Fang Song, Jing Zhang
Publikováno v:
ChemMedChem. 16:1600-1604
Pancreatic lipase (PL), a key target for the prevention and treatment of obesity, plays crucial roles in the hydrolysis and absorption of in dietary fat. In this study, a series of pyrazolones were synthesized and their inhibitory effects against PL
Publikováno v:
Synlett. 32:833-837
An efficient copper-catalyzed addition of arylboronic esters to (Boc)2O was developed. The reaction can be conducted under exceedingly mild conditions and is compatible with a variety of synthetically relevant functional groups. It therefore represen
Autor:
Shao-Jiang Song, Li-Wei Lu, Han Zhang, Xiao-Xiao Huang, Le Zhou, Rui Guo, Ye-Qing Du, Qing-Bo Liu
Publikováno v:
Journal of Natural Products. 84:20-25
The structural elucidation of chiral molecules with more than one stereocenter is usually a tricky problem. In this paper, efficient 1H NMR spectroscopic approaches for assigning the erythro and threo configurations of 1-oxygenated 1,2-diarylpropan-3
Publikováno v:
Organic & Biomolecular Chemistry. 19:3359-3369
Various β-indolyl sulfoximidoyl amides were efficiently prepared from ortho-iodoanilines, propargyl bromides, 1 atm of CO, and substituted NH-sulfoximines, through a palladium-catalyzed indole annulation/carbonyl insertion/C-N bond formation cascade
Publikováno v:
Main Group Chemistry. 18:427-436
This article has been retracted, and the online PDF has been watermarked “RETRACTION”. The retraction notice is available at http://doi.org/10.3233/MGC-220954.
Publikováno v:
Organic Process Research & Development. 23:2388-2393
N-Nitrodiethanolamine dinitrate (DINA) is a nitramine explosive containing both O-nitro and N-nitro groups. In this work, the synthesis of DINA by nitration of diethanolamine hydrochloride (DEAHC) ...
Autor:
Hsin-Ling Yang, Yan-Zhen Zhang, Li-Wei Wang, Yugandhar Vudhya Gowrisankar, Pei-Jane Huang, You-Cheng Hseu, Hung-Rong Yen, Xuan-Zao Chen
Publikováno v:
Redox Biology, Vol 44, Iss, Pp 102007-(2021)
Redox Biology
Redox Biology
Pterostilbene (Pt) is a natural polyphenol found in blueberries and several grape varieties. Pt's pharmacological importance was well documented. Nevertheless, the depigmenting effects are not demonstrated. We evaluated the Pt's depigmenting effects