Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ye Zheng"'
Autor:
Ryan C. Gimple, Guoxin Zhang, Linjie Zhao, Leo J.Y. Kim, Jia Z. Shen, Cheryl Kim, Briana C. Prager, Xujun Wang, Jean A. Bernatchez, Xiang-Dong Fu, Jeremy N. Rich, Kailin Yang, Jair L. Siqueira-Neto, Deobrat Dixit, Zhixin Qiu, Lukas Chavez, Zhe Zhu, Deguan Lv, Ye Zheng, Denise Hinz, Zhengyu Liang, Charles Spruck, Xiuxing Wang, Chunyu Jin, Qiyuan Yang, Qiulian Wu, Lihua Min, Katherine A. Jones, Zhen Dong, Shruti Bhargava
Publikováno v:
Cancer Discov
Glioblastoma (GBM) is the most lethal primary brain cancer characterized by therapeutic resistance, which is promoted by GBM stem cells (GSC). Here, we interrogated gene expression and whole-genome CRISPR/Cas9 screening in a large panel of patient-de
Autor:
Yuqiong Liang, Michael Downes, Theodore M. Kamenecka, Ruth T. Yu, Annette R. Atkins, Ye Zheng, Ronald M. Evans, Thomas P. Burris, Chin-San Loo, Laura A. Solt, Sagar P Bapat, Mathias Leblanc, Han Cho, Christina L. Chang, Xuan Zhao
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Th17 cells are a subset of T cells that produce interleukin 17 and other proinflammatory cytokines. They are involved in the development of autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. Previous studies illustr
Autor:
Joshua J. Coon, Gary M. Wilson, Ye Zheng, Jing Fan, Ruiqi Liao, Gretchen L. Seim, Yuannyu Zhang, Xin Liu, Jian Xu, Nobuyuki Tanimura, Sunduz Keles, Peiman Hematti, Emery H. Bresnick
Publikováno v:
Cell Reports, Vol 31, Iss 13, Pp 107832-(2020)
Cell Rep
Cell Rep
Summary: Protein ensembles control genome function by establishing, maintaining, and deconstructing cell-type-specific chromosomal landscapes. A plethora of small molecules orchestrate cellular functions and therefore may link physiological processes
Autor:
Ruiqi Liao, Emery H. Bresnick, Yuannyu Zhang, Jian Xu, Joshua J. Coon, Nobuyuki Tanimura, Matthew R. Dent, Peiman Hematti, Gary M. Wilson, Ye Zheng, Xin Liu, Miao Cao, Judith N. Burstyn, Sunduz Keles
Publikováno v:
Developmental cell. 46(5)
By functioning as an enzyme cofactor, hemoglobin component, and gene regulator, heme is vital for life. One mode of heme-regulated transcription involves amplifying the activity of GATA-1, a key determinant of erythrocyte differentiation. To discover
Autor:
Lauren A. Mack, Christopher Liddle, Sigal Gery, Zhengshan Chen, Qi Cao, Henry Yang, Xianping Shi, Xuan Zhao, Haibo Sun, De-Chen Lin, Qi Chen, Jonathan W. Said, Serhan Alkan, Jing-Wen Bai, Ruishu Deng, Ling Wa Chong, Markus Müschen, Michael Downes, Ronald M. Evans, Jian-Jun Xie, Han Cho, Ruth T. Yu, Annette R. Atkins, Ye Zheng, Quan Zhen Li, H. Phillip Koeffler
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 114, iss 47
The circadian system regulates numerous physiological processes including immune responses. Here, we show that mice deficient of the circadian clock genes Cry1 and Cry2 [Cry double knockout (DKO)] develop an autoimmune phenotype including high serum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec83e67eefb01b297a9051e42544974f
https://escholarship.org/uc/item/6wn972xv
https://escholarship.org/uc/item/6wn972xv
Publikováno v:
Immunity. 16:257-270
Despite the established role of dendritic cells (DCs) in regulating T lymphocyte activation, intracellular mechanisms responsible for controlling DC function are largely undefined. Here, we have studied DCs from mice deficient in the p50, RelA, and c
Autor:
Fan Wang, Wen Zhang, Jianhua Li, Min Wu, Zhenghong Yuan, Peng Xiuhua, Jieliang Chen, Junyu Lin, Cuncun Chen, Ye Zheng
The hepatitis B virus (HBV) is a DNA virus that can cause chronic hepatitis B (CHB) in humans. Current therapies for CHB infection are limited in efficacy and do not target the pre-existing viral genomic DNA, which are present in the nucleus as a cov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b60473638492d473db13a0c812ed396
https://europepmc.org/articles/PMC3916035/
https://europepmc.org/articles/PMC3916035/
Autor:
Junmei Wang, Shomyseh Sanjabi, Amer A. Beg, Ye Zheng, Sofia Hussain, Xingyu Wang, Fatah Ouaaz
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 178(11)
TLRs play a critical role in inducing inflammatory and immune responses against microbial agents. In this study, we have investigated the role of NF-κB transcription factors in regulating TLR-induced gene expression in dendritic cells, a key APC typ