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Autor:
Zay Htet, Mahzuz Karim
Publikováno v:
Journal of the Royal Society of Medicine. 114(7)
Recent years have seen a paradigm shift in the management of patients with diabetes mellitus. Rather than good glycaemic control being the sole primary aim, the therapeutic focus has broadened to consider potential additional cardiovascular and renal
Autor:
Teena Mohan, Larisa V. Gubareva
Publikováno v:
Cold Spring Harbor perspectives in medicine. 12(1)
The neuraminidase (NA) of influenza A and B viruses plays a distinct role in viral replication and has a highly conserved catalytic site. Numerous sialic (neuraminic) acid analogs that competitively bind to the NA active site and potently inhibit enz
Autor:
Tonya Orchard, Tial TinKai, Rachel M. Cole, A. Courtney DeVries, Rebecca Andridge, Kate Ormiston, Maryam B. Lustberg, Julie Fitzgerald, Monica M. Gaudier-Diaz
Publikováno v:
Nutritional neuroscience. 25(12)
Chemotherapy can result in toxic side effects in the brain. Intake of marine-based omega-3 polyunsaturated fatty acids (n-3 PUFAs), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), alter brain fatty acids, potentially improving brain funct
Autor:
Adam Ioannou
Publikováno v:
BMJ case reports. 14(11)
Takotsubo cardiomyopathy is characterised by left ventricular apical ballooning, in the absence of coronary artery disease, and classically occurs at times of intense stress. Due to the striking preponderance of Takotsubo cardiomyopathy occurring in
Publikováno v:
BMJ case reports. 14(11)
This is a case of a young woman who developed neurological and psychiatric symptoms 3 days after resection of an immature teratoma. She was diagnosed with anti-NMDA receptor encephalitis via positive serum antibody titres, which was later confirmed w
Publikováno v:
Cochrane Database Syst Rev
The Cochrane Library
The Cochrane Library
Inhaled antibiotics are commonly used to treat persistent airway infection with Pseudomonas aeruginosa that contributes to lung damage in people with cystic fibrosis. Current guidelines recommend inhaled tobramycin for individuals with cystic fibrosi
Autor:
Christopher O. Miles, Alexander K. Leynse, Alison Robertson, Elizabeth M. Mudge, Pearse McCarron
Publikováno v:
J Chromatogr B Analyt Technol Biomed Life Sci
Gambierdiscus spp. are epi-benthic dinoflagellates that have been associated with ciguatera poisoning. These microalgae can have complex secondary metabolite profiles including ciguatoxins, maitotoxins, and gambierones, with varying compositions and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50204503654d059c06bc042c487e56cd
https://nrc-publications.canada.ca/eng/view/object/?id=ed81c52b-e8b5-47c9-964c-0608c19c2133
https://nrc-publications.canada.ca/eng/view/object/?id=ed81c52b-e8b5-47c9-964c-0608c19c2133
Autor:
Lorinda Simms, Shehkar Patil, David R. Gandara, Anders Mellemgaard, Raghunadharao Digumarti, Bonne Biesma, Johan Vansteenkiste, Mauro Zukin, Joachim von Pawel, Katherine P. Sugarman, Keunchil Park, Christian Manegold, Filippo de Marinis, Tuncay Göksel, Janusz Rolski, Piotr Serwatowski, Jin S. Lee, Giorgio V. Scagliotti, Ulrich Gatzemeier, Purvish M. Parikh
Publikováno v:
Journal of Clinical Oncology. 41:2458-2466
PURPOSE Cisplatin plus gemcitabine is a standard regimen for first-line treatment of advanced non–small-cell lung cancer (NSCLC). Phase II studies of pemetrexed plus platinum compounds have also shown activity in this setting. PATIENTS AND METHODS
Autor:
David H. Johnson, Roy S. Herbst, Corey J. Langer, Louis Fehrenbacher, William Novotny, Eric Holmgren, Jacques Gaudreault, John Nemunaitis, David M. Jablons, Fairooz F. Kabbinavar, Russell F. DeVore, Lisa A. Damico
Publikováno v:
Journal of Clinical Oncology. 41:2305-2312
Purpose To investigate the efficacy and safety of bevacizumab plus carboplatin and paclitaxel in patients with advanced or recurrent non-small-cell lung cancer. Patients and Methods In a phase II trial, 99 patients were randomly assigned to bevacizum
Autor:
Julian M. Jimenez, Chenwei Duan, Craig J. Goergen, Abigail Cox, Preeti M. Sivasankar, Sarah Calve
Publikováno v:
J Voice
Summary Objectives The understanding of vocal fold hydration state, including dehydrated, euhydrated, rehydrated tissue, and how hydration affects vocal fold biomechanical properties is still evolving. Although clinical observations support the benef