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Autor:
Martin Haluzik, Peter Novodvorský
Publikováno v:
Expert Opinion on Drug Safety. 21:349-361
Introduction Recent development of novel antidiabetic drugs with proven cardiovascular (CV) and renal benefit and positive effect on body weight enable to take a more complex approach toward the management of type 2 diabetes mellitus (T2DM). Fixed-ra
Publikováno v:
Journal of Dietary Supplements. 20:391-410
Depression is a severely debilitating psychiatric disorder that influences more than 15% of the population worldwide. It has been demonstrated that it is associated with a high risk of developing other diseases such as cardiovascular diseases, diabet
Autor:
Maurizio de Martino, Luisa Galli, Marco Antonio Motisi, Agnese Tamborino, Sara Parigi, Elena Chiappini
Publikováno v:
Journal of Chemotherapy. 34:73-86
Viral infections are particularly common among children. They often have a mild course, are self-limiting and do not need any specific treatment. However, in some cases, the disease can be severe and lead to permanent disabilities. A variety of antiv
Autor:
Caroline Fenton, Connie Kang
Publikováno v:
Drugs & Therapy Perspectives. 37:503-507
Cutaneous warts, common in children and immunocompromised patients, can be painful and socially and functionally restricting. Caused by several human papillomavirus types, they may resolve spontaneously or respond to traditional treatments. If not, p
Autor:
Iain Gardner, Oliver Hatley, Lisa Almond, Ben G Small, Klaus Romero, Mian Zhang, Helen Humphries, Xian Pan, Masoud Jamei, Alexander Berg
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 11, Pp 1382-1395 (2021)
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 11, Pp 1382-1395 (2021)
Tuberculosis (TB) remains a global health problem and there is an ongoing effort to develop more effective therapies and new combination regimes that can reduce duration of treatment. The purpose of this study was to demonstrate utility of a physiolo
Publikováno v:
J Antimicrob Chemother
Background The cyclic anionic lipopeptide daptomycin is used in the treatment of severe infections caused by Gram-positive pathogens, including MRSA. Daptomycin resistance, although rare, often results in treatment failure. Paradoxically, in MRSA, da
Autor:
H.J.M. van Kan, Peter E. Spronk, E. J F Franssen, T H Geersing, P. H. J. van der Voort, M den Reijer
Publikováno v:
The Journal of antimicrobial chemotherapy, 77(1), 246-252. Oxford University Press
Background Continuous infusion of conventional amphotericin B (CCAB) is used in ICUs for pre-emptive treatment of invasive fungal infections. Amphotericin B has previously been associated with nephrotoxicity. Objectives To investigate if CCAB with th
Autor:
Thomas P. Lodise, Monique R Bidell
Publikováno v:
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. 41:915-931
Oral tetracyclines have been used in clinical practice for over 60 years. One of the most common indications for use of oral tetracyclines is for treatment of adult outpatients with skin and soft infections (SSTIs), including acute bacterial skin and
Autor:
Masahiro Sugawara, Yoshihiko Saito, Takahiro Hayashi, Kenichi Tsujita, Shinya Hiramitsu, Masako Waki, Yutaka Wakasa, Naoto Yokota, Naoki Kawai, Hisao Mori, Hideaki Jinnouchi, Ichiro Hisatome, Kunihiko Matsui, Hisao Ogawa, Kazuo Kimura, Yusuke Ohya, Kazuaki Uchiyama, Sunao Kojima, Febuxostat for Cerebral, Hirokazu Kakuda, Cardiorenovascular Events Prevention Study (Freed) investigators, Eiichi Tokutake
Publikováno v:
Rheumatology. 61:2346-2359
Objectives Hyperuricaemia is recognized as an independent risk marker for cardiovascular and renal diseases. However, uric acid is a powerful free-radical scavenger, and the optimal level of serum uric acid (SUA) determining outcomes is unknown. This
Autor:
Tieli Zhou, Tao Chen, Wenya Xu, Ye Xu, Wenli Liao, Jianzhong Ye, Huaiyu Jia, Weiliang Zeng, Ying Zhang, Qing Wu, Jianming Cao
Publikováno v:
Infection and Drug Resistance. 14:4395-4407
Huaiyu Jia,1 Ying Zhang,2 Jianzhong Ye,1 Wenya Xu,1 Ye Xu,1 Weiliang Zeng,2 Wenli Liao,1 Tao Chen,1 Jianming Cao,2 Qing Wu,1 Tieli Zhou1 1Department of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejian