Zobrazeno 1 - 10
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pro vyhledávání: ''
Autor:
Lorinda Simms, Shehkar Patil, David R. Gandara, Anders Mellemgaard, Raghunadharao Digumarti, Bonne Biesma, Johan Vansteenkiste, Mauro Zukin, Joachim von Pawel, Katherine P. Sugarman, Keunchil Park, Christian Manegold, Filippo de Marinis, Tuncay Göksel, Janusz Rolski, Piotr Serwatowski, Jin S. Lee, Giorgio V. Scagliotti, Ulrich Gatzemeier, Purvish M. Parikh
Publikováno v:
Journal of Clinical Oncology. 41:2458-2466
PURPOSE Cisplatin plus gemcitabine is a standard regimen for first-line treatment of advanced non–small-cell lung cancer (NSCLC). Phase II studies of pemetrexed plus platinum compounds have also shown activity in this setting. PATIENTS AND METHODS
Autor:
David H. Johnson, Roy S. Herbst, Corey J. Langer, Louis Fehrenbacher, William Novotny, Eric Holmgren, Jacques Gaudreault, John Nemunaitis, David M. Jablons, Fairooz F. Kabbinavar, Russell F. DeVore, Lisa A. Damico
Publikováno v:
Journal of Clinical Oncology. 41:2305-2312
Purpose To investigate the efficacy and safety of bevacizumab plus carboplatin and paclitaxel in patients with advanced or recurrent non-small-cell lung cancer. Patients and Methods In a phase II trial, 99 patients were randomly assigned to bevacizum
Autor:
Kullervo Hynynen, Vlad Agache, David E. Goertz, Raffi Karshafian, Margarita Todorova, Branson Chen, Omid Mortazavi
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52307 (2012)
PLoS ONE
PLoS ONE
Ultrasound stimulated microbubbles (USMB) are being investigated for their potential to promote the uptake of anticancer agents into tumor tissue by exploiting their ability to enhance microvascular permeability. At sufficiently high ultrasound trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41f9f11662324da4f80905974fc88751
https://doi.org/10.32920/14668866
https://doi.org/10.32920/14668866
Autor:
Foteinos-Ioannis Dimitrakopoulos, Kyriaki Papadopoulou, Dimitrios Pectasides, Anna Batistatou, Kitty Pavlakis, George Fountzilas, Helen P. Kourea, Sofia Chrisafi, George Pentheroudakis, Vassiliki Kotoula, Pavlos Papakostas, Eleni Galani, Eleni Res, Dimitrios Bafaloukos, Angelos Koutras, Georgia-Angeliki Koliou, Mattheos Bobos, Kyriakos Chatzopoulos, Anthoula Asimaki-Vlachopoulou
Publikováno v:
Cancer Research and Treatment. 54:1053-1064
Purpose Angiogenesis is a crucial phenomenon in the development and progression of breast cancer (BC), but the clinical significance of angiogenesis-related proteins in metastatic BC remains unknown. This study investigates the prognostic value of va
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 37:673-683
Background: Triple-negative breast cancer (TNBC) is the most serious subtype of breast cancer (BC) and has been a great health threat to females. Although chemotherapeutic agent contributes a lot to TNBC treatment, drug resistance has been a great ob
Autor:
Lauren Schaff, Christian Grommes
Publikováno v:
Blood. 140:971-979
Primary central nervous system lymphoma (PCNSL) is a rare extranodal lymphomatous malignancy that affects the brain, spinal cord, leptomeninges, or vitreoretinal space, without evidence of systemic involvement. The diagnosis of PCNSL requires a high
Publikováno v:
Recent Patents on Anti-Cancer Drug Discovery. 17:268-283
Background: The ubiquitin-proteasome system (UPS) is critical in cellular protein degradation and widely involved in the regulations of cancer hallmarks. Targeting the UPS pathway has emerged as a promising novel treatment in hematological malignanci
Autor:
A.G. Van Der Heijden, L.A.L.M. Kiemeney, Niven Mehra, Richard P. Meijer, M.S. Van Der Heijden, Anke Richters, Joost L. Boormans, Katja K.H. Aben
Publikováno v:
European Urology Focus, 8, 995-1002
European Urology Focus, 8, 4, pp. 995-1002
European Urology Focus, 8(4), 995-1002. Elsevier
European Urology Focus, 8, 4, pp. 995-1002
European Urology Focus, 8(4), 995-1002. Elsevier
Background: Cisplatin is preferred to carboplatin when treating metastatic urothelial carcinoma of the bladder (mUCB), despite its greater toxicity. Randomised studies underpinning this have been performed in noncontemporary populations with limitati
Autor:
Xin Chen, Xinhui Li, Xiangmei Zhang, Jidong Zhao, Yang Zhao, Yunjiang Liu, Liyan Zhao, Dan Li, Ming He, Jie Li
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 37:324-331
Background: We conducted a trial to evaluate the efficacy and safety of apatinib, a tyrosine inhibitor against vascular endothelial growth factor receptor 2, combined with neoadjuvant chemotherapy ...
Autor:
Otis W. Brawley, Jeromie Ballreich, Lin Wang, Hwanhee Hong, Channing J. Paller, G. Caleb Alexander
Publikováno v:
Value Health
Objectives To assess the cost-effectiveness of systemic treatments for metastatic castration-sensitive prostate cancer from the US healthcare sector perspective with a lifetime horizon. Methods We built a partitioned survival model based on a network