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Autor:
Sanaz Keshavarz Shahbaz, Muhammed Majeed, Amirhossein Sahebkar, Khadijeh Koushki, Thozhukat Sathyapalan
Publikováno v:
Current Neuropharmacology. 20:309-323
Progressive degeneration and dysfunction of the nervous system because of oxidative stress, aggregations of misfolded proteins, and neuroinflammation are the key pathological features of neurodegenerative diseases. Alzheimer's disease is a chronic ne
Autor:
Tomomi Kuwahara, Hitoshi Yamaoka, A. Hajime Koyama, Tomohiko Fujisawa, Tamiko Nagao, Haruyuki Nakayama-Imaohji, Hisataka Goda, Ayano Tada
Publikováno v:
Journal of Infection and Chemotherapy. 28:67-72
Introduction Human norovirus (HuNoV) is a leading cause of infectious gastroenteritis. Since HuNoV shows resistance to alcohol, chlorine-based sanitizers are applied to decontaminate the virus on environmental surfaces. Chlorous acid water (CA) has b
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 17, Iss, Pp 84-91 (2021)
International Journal for Parasitology: Drugs and Drug Resistance
International Journal for Parasitology: Drugs and Drug Resistance
Benzimidazole (BZ) drugs are frequently used to treat infections with the equine ascarid Parascaris univalens due to increasing resistance to macrocyclic lactones and pyrantel. Benzimidazole resistance is rare in ascarids in contrast to strongyle par
Autor:
Bryan K. Yamamoto, Eric A. Rodriguez
Publikováno v:
Current Neuropharmacology. 19:2092-2107
Methamphetamine (Meth) abuse presents a global problem and commonly occurs with stress and/or alcohol use disorders. Regardless, the biological causes and consequences of these comorbidities are unclear. Whereas the mechanisms of Meth, stress, and al
Autor:
Xiu-Min Lu, Yong-Tang Wang, Xing-Dong Chen, Hua Huang, Shuang Feng, Feng-Nian Lu, Jun-Jie Tang
Publikováno v:
Current Neuropharmacology. 19:2180-2187
Chlorogenic acid (CGA) is a kind of traditional Chinese medicine, abundant in honeysuckle and eucommia, and has a wide range of biological activities, and pharmacological effects. Previous studies have shown that CGA can regulate learning, memory, co
Publikováno v:
Current Drug Safety. 16:252-258
Background: Clopidogrel has been commonly prescribed as a selective P2Y12 receptor antagonist to reduce heart attack and stroke risk. Nearly 10% of absorbed clopidogrel is metabolized to active forms by cytochrome P450 (CYP) enzymes in the liver and
Autor:
Fidel Martínez-Gutiérrez, Denisse de Loera, Lluvia Itzel López-López, Cecilia Villarreal-Reyes, Ernesto Rivera-Avalos
Publikováno v:
Chemotherapy. 67:102-109
Background: The synthesis and biological evaluation of 1,4-naphthoquinone derivatives are of great interest since these compounds exhibit strong antibacterial, antifungal, antimalarial, and anticancer activities. The electronic properties of naphthoq
Publikováno v:
Journal of Dietary Supplements. 20:284-311
The genomic reshuffling, mutagenicity, and high transmission rate of the SARS-CoV-2 pathogen highlights an urgent need for effective antiviral interventions for COVID-19 control. Targeting the highly conserved viral genes and/or gene-encoded viral pr
Publikováno v:
Tropical Journal of Pharmaceutical Research; Vol. 20 No. 10 (2021); 2213-2218
Purpose: To determine the curative impact of mesalazine (MSZ)-BTVCs combination on ulcerative colitis (UC), and its influence on inflammation and oxidative stress in the patients.Methods: 100 UC patients were randomely assigned to a control group giv
Publikováno v:
Tropical Journal of Pharmaceutical Research; Vol. 20 No. 10 (2021); 2029-2034
Purpose: To investigate the effect of forsythiaside A on heart failure.Methods: An in vitro cell model of myocardial injury was established by incubating H9c2 primary cardiomyocytes with hydrogen peroxide (H2O2). Apoptosis was measured by flow cytome