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Autor:
Chiara Finocchiaro, Simona Toscano, Salvatore Lo Fermo, Francesco Patti, Enrico Millefiorini, Eleonora Sgarlata, Clara Grazia Chisari
Publikováno v:
Current Neuropharmacology. 20:1978-1987
Background: Progressive Multifocal Leukoencephalopathy (PML) is an opportunistic infection caused by John Cunningham virus (JCV) reactivation, potentially associated with natalizumab (NTZ) treatment for Multiple Sclerosis (MS). The anti-JCV antibodie
Publikováno v:
Exp Clin Psychopharmacol
Experimental and clinical psychopharmacology, vol 30, iss 3
Experimental and clinical psychopharmacology, vol 30, iss 3
Research on nicotine metabolism has primarily focused on white adults. This study examined associations between nicotine metabolism, tobacco use, and demographic characteristics among Alaska Native adults who smoke cigarettes. Participants (N = 244)
Autor:
Daniel Moj, Nicola Ammer, Babette Aicher, Jan-Georg Wojtyniak, Thorsten Lehr, Michael Teifel, Herbert Sindermann, Hannah Britz, Nina Hanke
Zoptarelin doxorubicin is a fusion molecule of the chemotherapeutic doxorubicin and a luteinizing hormone-releasing hormone receptor (LHRHR) agonist, designed for drug targeting to LHRHR positive tumors. The aim of this study was to establish a physi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28c5e9a18956370d7aca5ee1061fd910
Publikováno v:
Cannabis Cannabinoid Res
INTRODUCTION: Cannabidiol (CBD) is a major cannabinoid extracted from Cannabis sativa with no abuse potential. Data from recent rodent studies suggest that amelioration of alcohol-motivated behaviors may be one of the numerous pharmacological effects
Publikováno v:
Exp Clin Psychopharmacol
Protein kinase C (PKC) is important for the mechanism of action of amphetamine (AMPH). Inhibiting PKC blocks AMPH-stimulated increases in extracellular dopamine levels and AMPH-stimulated locomotor activity. This study examined the effects of PKC inh
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics. 37:556-564
Purpose: To investigate the influence of benzalkonium chloride (BAK) on ocular surface disease (OSD) in glaucoma patients receiving ocular-hypotensive agent. Methods: Patients were randomized to re...
Publikováno v:
Current Drug Safety. 16:259-263
Background: Colistin utilization has gradually increased worldwide with the rising of multidrug-resistant (MDR) gram-negative bacilli despite its nephrotoxicity. Lipid emulsion (LE) is widely used for the toxic overdose treatment of various drugs. Ob
Autor:
Jun Li, Hong Zhou, Yan Yao, Junfa Yang, Ying Hu, Shuang Hu, Tao Xu, Shu-xian Wang, Jing-Li Min, Chen-chen Yang, Ze-Yuan Wei, Yin-Cui Wu, Liang-yun Li
Publikováno v:
Acta Pharmacol Sin
Acetaminophen (APAP) is one of the major causes of drug-induced acute liver injury, and ethanol may aggravate APAP-induced liver injury. The problem of ethanol- and APAP-induced liver injury becomes increasingly prominent, but the mechanism of ethano
Autor:
Ali Unlu, Gulsum Abusoglu, Fatma Humeyra Yerlikaya, Dilek Tezcan, Duygu Eryavuz Onmaz, Sema Yilmaz, Mustafa Onmaz, Sedat Abusoglu
Publikováno v:
Inflammopharmacology
Hydroxychloroquine has attracted attention in the treatment of COVID-19. Many conflicting findings have been reported regarding the efficacy and safety of this drug, which has been used safely in the rheumatological diseases for years. However, these
Publikováno v:
British Journal of Clinical Pharmacology. 88:1885-1896
Aim: Metamizole (dipyrone) is a prodrug not detectable in serum or urine after oral ingestion. The primary metabolite is 4-methylaminoantipyrine (4-MAA), which can be N-demethylated to 4-aminoantipyrine (4-AA) or oxidized to 4-formylaminoantipyrine (