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Autor:
Sabina Holland, Soya S. Sam, Allison DeLong, Samuel Ayaya, Akarsh Manne, Ashley Chory, Angela M. Caliendo, Joseph W. Hogan, Eslyne Jepkemboi, Rachel C. Vreeman, Winstone Nyandiko, Millicent Orido, Rami Kantor, Vladimir Novitsky, Josephine Aluoch, Anthony Ngeresa
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 89:231-239
BACKGROUND Long-term impact of drug resistance in perinatally-infected children and adolescents living with HIV (CALWH) is poorly understood. We determined drug resistance and examined its long-term impact on failure and mortality in Kenyan CALWH fai
Publikováno v:
Journal of Infection and Chemotherapy. 28:29-34
As a newly emerging pathogen, Candida auris has spread rapidly and caused a serious invasive infection. Candida auris often appeared high resistance to classical antifungal drugs. Drug combination therapy is emerging as an effective and well-establis
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 17, Iss, Pp 84-91 (2021)
International Journal for Parasitology: Drugs and Drug Resistance
International Journal for Parasitology: Drugs and Drug Resistance
Benzimidazole (BZ) drugs are frequently used to treat infections with the equine ascarid Parascaris univalens due to increasing resistance to macrocyclic lactones and pyrantel. Benzimidazole resistance is rare in ascarids in contrast to strongyle par
Autor:
Carlos Tong Rios, Julia Penna-Coutinho, Jansen Fernandes Medeiros, Nubia Boechat, Antoniana U. Krettli, Dhelio Batista Pereira, Maisa da Silva Araujo, Anna Caroline Campos Aguiar, Paula Miranda Sá
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 17, Iss, Pp 150-155 (2021)
International Journal for Parasitology: Drugs and Drug Resistance
International Journal for Parasitology: Drugs and Drug Resistance
Human malaria continues to be a public health problem and an important cause of morbidity and mortality in the world. Malaria control is achieved through both individual protection against mosquito bites and drug treatment, which is hampered by the s
Autor:
Ajib Diptyanusa, Ika Puspa Sari
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 17, Iss, Pp 128-138 (2021)
International Journal for Parasitology: Drugs and Drug Resistance
International Journal for Parasitology: Drugs and Drug Resistance
The global burden of diarrhea caused by Cryptosporidium parasite is underestimated. In immunocompromised hosts, chronic and severe presentation of intestinal cryptosporidiosis can result in long-term morbidity and high illness costs. The evidence of
Autor:
Prapon Wilairat, Maria G. Gomez-Lorenzo, Thanat Chookajorn, Kesinee Chotivanich, Krittikorn Kümpornsin, Laura M. Sanz, Cristina de Cozar, Marcus C. S. Lee, Namfon Kotanan, Duangkamon Loesbanluechai, Nicholas J. White, Francisco-Javier Gamo
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 17, Iss, Pp 186-190 (2021)
International Journal for Parasitology: Drugs and Drug Resistance
International Journal for Parasitology: Drugs and Drug Resistance
Emerging artemisinin resistance in Plasmodium falciparum malaria has the potential to become a global public health crisis. In Southeast Asia, this phenomenon clinically manifests in the form of delayed parasite clearance following artemisinin treatm
Publikováno v:
Journal of Chemotherapy. 34:166-172
Several antimicrobial combination therapies are used to treat multiple drug resistant (MDR) and extensively drug resistant (XDR) Acinetobacter baumannii infections. A novel antibiotic, eravacycline, shows a higher potency than tigecycline. The effica
Autor:
Gilles Peytavin, Florence Damond, Sophie Matheron, A. Bachelard, Samuel Lebourgeois, Gilles Collin, Charlotte Charpentier, Jade Ghosn, Quentin Le Hingrat, Diane Descamps, Valentine Marie Ferré
Publikováno v:
Journal of Antimicrobial Chemotherapy. 77:409-412
Background HIV-2 resistance to integrase strand-transfer inhibitors (INSTIs) is characterized by two main pathways: (i) mutations at codons 143, 148 and155; and (ii) amino acid insertion after integrase codon 231 (231ins). Objectives To complete INST
Autor:
Ravindra K. Gupta, Judith Breuer, Sunando Roy, Caroline A. Sabin, Obinna Ogbanufe, Man Charurat, Rawlings Datir, Fati Murtala-Ibrahim, Patrick Dakum, Vivian Kwaghe, Nicaise Ndembi, Kate El Bouzidi, Dan Frampton
Publikováno v:
Journal of Antimicrobial Chemotherapy
Background Deep sequencing could improve understanding of HIV treatment failure and viral population dynamics. However, this tool is often inaccessible in low- and middle-income countries. Objectives To determine the genetic patterns of resistance em
Five Years With Dolutegravir Plus Lamivudine as a Switch Strategy: Much More Than a Positive Finding
Autor:
Andrea Giacometti, Gabriella d'Ettorre, Amedeo Capetti, William Gennari, Stefano Rusconi, Gaetana Sterrantino, Andrea Giacomelli, Vanni Borghi, Gianmaria Baldin, Alessandra Latini, Andrea De Vito, Cristina Mussini, Arturo Ciccullo, Simona Di Giambenedetto, Giordano Madeddu, Maria Vittoria Cossu
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 88:234-237
BACKGROUND Results from clinical trials and observational studies suggest that dolutegravir plus lamivudine could be an effective and well-tolerated option for simplification in HIV-1-positive patients. We aimed to assess long-time efficacy and safet