Zobrazeno 1 - 10
of 11 070
pro vyhledávání: ''
Autor:
Hayk Ghukasyan, Thuy Le, Cecilia M. Shikuma, Nath Limpruttdham, Trieu Ly Vo, Lishomwa C. Ndhlovu, Louie Mar A Gangcuangco, Glen M. Chew, Thomas A. Premeaux, Robert H. Paul, Thao Vu Phuong, Dominic C. Chow, Van Vinh Chau Nguyen, Chathura Siriwardhana
Publikováno v:
AIDS Res Hum Retroviruses
The impact of HIV antiretroviral therapy (ART) on immune dysregulation associated with hepatitis C virus (HCV)/HIV coinfection is incompletely understood. We serially assessed monocyte activation (neopterin, sCD14, and sCD163) and T cell activation (
Autor:
Kai Yang, Shuyu Chen, Difei Li, Shanshan Zha, Li Yu, Zhenyu Liang, Shengming Liu, Zhuoyu Chen, Yao Deng, Rongchang Chen
Publikováno v:
Allergology International, Vol 71, Iss 1, Pp 73-82 (2022)
Background Accumulating evidence indicated the crucial role for interleukin 6 (IL-6) signaling in the development of allergic asthma. Yet, the role of IL-6 signaling in toluene diisocyanate (TDI)-induced mixed granulocytic airway inflammation still r
Autor:
Geraldine Cambridge, David A. Isenberg, Loren Kell, Samuel J Taylor, Maria J. Leandro, Kavina Shah, Ruth J Pepper, Venkat Reddy, Mark S. Cragg, Scott R. Henderson, Christian Klein
Publikováno v:
Rheumatology. 61:2894-2904
Objectives To investigate key factors that may contribute to the variability of rituximab-mediated peripheral and renal B cell depletion (BCD) in SLE. Methods We analysed: (i) CD19+ B cell counts in patients with SLE before and 1, 2, 3 and 6 months a
Autor:
So Jeong Kim, Sun Chang Kim, Mi-Yeon Kim, Hyo Jeong Kim, Hun Sik Kim, Jinju Lee, Woo Sun Choi
Publikováno v:
Journal of Ginseng Research, Vol 45, Iss 6, Pp 695-705 (2021)
Journal of Ginseng Research
Journal of Ginseng Research
Background Ginsenosides have beneficial effects on several airway inflammatory disorders primarily through glucocorticosteroid-like anti-inflammatory activity. Among inflammatory cells, eosinophils play a major pathogenic role in conferring a risk of
Publikováno v:
Current Opinion in Nephrology & Hypertension. 31:36-46
Purpose of review Severe COVID-19 disease is often complicated by acute kidney injury (AKI), which may transition to chronic kidney disease (CKD). Better understanding of underlying mechanisms is important in advancing therapeutic approaches. Recent
Autor:
Magda Said A. Abdeltawab, Shady E. Anis, Bahaa-Eldin A. Khaled, Amany A. Abdel-Aal, Manal A. Badawi, Marwa A. Hassan, Mona El-Sherbini, Marwa A. EL-Dardiry, Asmaa Ahmed Abdel-Aal, Abeer S A Al-Antably
Publikováno v:
Parasites & Vectors, Vol 14, Iss 1, Pp 1-13 (2021)
Parasites & Vectors
Parasites & Vectors
Background Mast cells are known to affect the primary and secondary immune responses against parasites, and this effect is partially mediated through the release of pro-angiogenic mediators. The aim of this study was to explore the effect of the mast
Autor:
Kenji Kufukihara
Publikováno v:
Clinical and Experimental Neuroimmunology. 12:228-237
Multiple sclerosis (MS) has long been considered a T-cell-mediated autoimmune disease of the central nervous system. However, newer evidence shows that B cells play a crucial role in the pathogenesis of MS via antibody production, antigen presentatio
Publikováno v:
Immunologic Research. 70:97-105
Acute lung injury (ALI) is a severe complication of sepsis and hemorrhagic shock with high morbidity. In the present study, the protective effect of Azilsartan on lipopolysaccharide (LPS)-induced ALI in mice was investigated to explore the potential
Publikováno v:
Annals of Neurology. 90:834-839
The frequency of CD20+ T cells was reported to be increased in several inflammatory conditions. We report that in patients with multiple sclerosis (MS), CD20+ T cells display a distinct proinflammatory phenotype with pathogenic properties. Anti-CD20
Autor:
Michelle A Cai, Timothy J. Ley, Lukas D. Wartman, Sridhar Nonavinkere Srivatsan, Timothy P Rooney, Sai Mukund Ramakrishnan, Christopher A. Miller, Nichole M. Helton, Casey D.S. Katerndahl, Ryan B. Day, Olivia R S Rogers, Mieke Hoock
Publikováno v:
Blood
Most patients with acute promyelocytic leukemia (APL) can be cured with combined all-trans retinoic acid (ATRA) and arsenic trioxide therapy, which induces the destruction of PML-RARA, the initiating fusion protein for this disease. However, the unde