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Publikováno v:
Clinical and Translational Science. 15:771-781
Amiodarone and its main metabolite, desethylamiodarone, are highly distributed to serum lipoproteins such as very-low-density lipoprotein (VLDL) and low-density lipoprotein (LDL), which are the carriers of triglyceride and cholesterol. This study aim
Publikováno v:
Hormone Molecular Biology and Clinical Investigation. 43:199-205
Objectives To evaluate the anticancer effects of calcitriol and cholecalciferol against different cell lines of breast cancer in monotherapy settings and in combination with raloxifene. Methods The antiproliferative, anti-migratory, and apoptotic ind
Autor:
Andrey Sivkov, Svetlana Sivkova, Roman V. Gorenkov, Sergey Sivkov, Natalya P. Chernus, Tamara Savina
Publikováno v:
Lipids in Health and Disease, Vol 20, Iss 1, Pp 1-9 (2021)
Lipids in Health and Disease
Lipids in Health and Disease
Background To determine the effect of genetic polymorphism of drug transporters on the efficacy of treatment with Rosuvastatin, Atorvastatin and Simvastatin in patients with hyperlipidemia. Methods The study consists of 180 patients, aged 40–75 yea
Autor:
Jiacheng Lai, Qingtong Wang, Meili Dong, Bin Li, Jingshu Ni, Yikun Wang, Chongjian Huang, Yongsheng Han
Publikováno v:
Lipids in Health and Disease, Vol 20, Iss 1, Pp 1-9 (2021)
Lipids in Health and Disease
Lipids in Health and Disease
Background Lipid management is the first line of treatment for decreasing the incidence of cardiovascular events in patients with coronary heart disease (CHD), and a variety of indicators are used to evaluate lipid management. This work analyses the
Autor:
L.L. Pavlovskyi
Publikováno v:
GASTROENTEROLOGY. 54:96-100
Background. Ceramides are the fats of the sphingolipid family that are involved in the development of insulin resistance, non-alcoholic fatty liver disease, and type 2 diabetes. Despite the standards of treatment for these diseases, there is currentl
Autor:
V.V. Poltorak
Publikováno v:
INTERNATIONAL JOURNAL OF ENDOCRINOLOGY; № 4.76 (2016); 59-72
Международный эндокринологический журнал-Mìžnarodnij endokrinologìčnij žurnal; № 4.76 (2016); 59-72
Міжнародний ендокринологічний журнал-Mìžnarodnij endokrinologìčnij žurnal; № 4.76 (2016); 59-72
Международный эндокринологический журнал-Mìžnarodnij endokrinologìčnij žurnal; № 4.76 (2016); 59-72
Міжнародний ендокринологічний журнал-Mìžnarodnij endokrinologìčnij žurnal; № 4.76 (2016); 59-72
This review examines the new formulation of insulin glargine (recombinant) in the form of injections 300 U/ml (Gla‑300, Toujeo®). Gla‑300 is a next generation basal insulin with a novel formulation of insulin glargin delivering the same amount o
Autor:
Hao Yao, Yuwei Zhu, Wenxue Tong, Jiankun Xu, Bingyang Dai, Le Huang, Ling Qin, Dick Ho Kiu Chow, Xu Li
Publikováno v:
Bioactive Materials, Vol 6, Iss 8, Pp 2511-2522 (2021)
Bioactive Materials
Bioactive Materials
Introduction Magnesium (Mg) has a prophylactic potential against the onset of hyperlipidemia. Similar to statin, Mg is recommended as lipid-lowering medication for hypercholesterolemia and concomitantly exhibits an association with increased bone mas
Autor:
Şeyma Osmanlıoğlu, Hakan Parlakpinar, Onural Ozhan, Azibe Yildiz, Merve Goksin Karaaslan, Nigar Vardi
Publikováno v:
Biotechnic & Histochemistry. 97:261-268
Valproate (VPA) induced changes in ovarian morphology are observed in humans with epilepsy and in non-epileptic animals. The effects of lamotrigine (LTG) on female reproduction is not well known. We investigated whether LTG might be a safer drug for
Autor:
Austin Reuter, Samantha Pabich, Rachel J. Fenske, Alicia M Weeks, Dawn Belt Davis, Chinmai Patibandla, Elizabeth D. Cox, Harpreet K Sandhu, Randall Nall, Cecilia E Kaiser, Margaret Punt, Nathan A. Truchan, Allison L. Brill, Michelle E. Kimple, Darby C. Peter, Benjamin Wancewicz, Ying Ge, Jeffrey M. Harrington, Michael Daniels
Publikováno v:
ACS Pharmacol Transl Sci
We and others previously reported increased signaling through the Prostaglandin E3 Receptor (EP3), a G protein-coupled receptor (GPCR) for the arachidonic acid metabolite, prostaglandin E2 (PGE2), is associated with {beta}-cell dysfunction of type 2
Autor:
Dalia M. Badary, Lobna A. Abdelzaher, Ahmed M. Abd-Eldayem, Sulaiman Alnasser, Mohammad Salem Hareedy
Publikováno v:
Néphrologie & Thérapeutique. 17:160-167
Background and aim The current study investigated the effects of treatment with 300 mg/kg valproic acid on rhabdomyolysis and acute kidney injury induced by intramuscular injection of hypertonic glycerol in rats. Methods Four groups of male wistar ra