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Autor:
Mingli Zuo, Yanfeng He, Yi Bao, Xiangyun Gai, Yongxin Liang, Pengcheng Lin, Dianxiang Lu, Gazang Zhaxi, Yuhua Ma, Cairang Nanjia, Zhanqiang Li, Xuehua Wu
Publikováno v:
Journal of Pharmacological Sciences, Vol 144, Iss 4, Pp 237-244 (2020)
Hypoxic pulmonary hypertension (HPH) is a progressive and irreversible disease that reduces survival. Echinacoside is a phenylethanoid glycoside from Tibetan herbs known for its vasorelaxant effect and for inhibiting the proliferation of rat pulmonar
Autor:
M Massányi, M Halo, L Strapáková, T Slanina, P Ivanič, E Strapáková, P Strapák, A Greń, G Formicki, P Massányi
Publikováno v:
Physiol Res
The goal of this study was to observe the effect of resorcinol on motility, viability and morphology of bovine spermatozoa. The semen was used from six randomly chosen breeding bulls. Ejaculate was diluted by different solutions of resorcinol in 1:40
Publikováno v:
Archives of Pharmacal Research. 43:553-566
Parkinson's disease (PD) is a multifactorial neurodegenerative disease manifesting mitochondrial damages and neuroinflammation. Qi is defined as a natural power that can regulate the energy flow in Oriental medicine, whereas mitochondria generate ene
Autor:
Clébio Pereira Ferreira, Julio Cesar Silva Nascimento, Andresca dos Santos de Oliveira, Patrícia Rodrigues de Lima, Flávia Denise da Silva Pereira, Rafael Torres de Souza Rodrigues, Salete Alves de Moraes, Mário Adriano Ávila Queiroz, Daniel Ribeiro Menezes, Lais Micaelle Lopes Moura
Publikováno v:
Tropical Animal Health and Production. 52:2433-2441
The aim of this study was to evaluate the effect of adding different concentrations of either urea or NaOH in dehydrated acerola (Malpighia emarginata) fruit residue (DAFR) on chemical composition, in vitro rumen degradability, and gas and methane pr
Autor:
Hamed Sadatfaraji, Marzie Boskabady, Zahra Gholamnezhad, Bahman Emami, Saeideh Saadat, Mohammad Hossein Boskabady, Farzaneh Shakeri, Vahab Azmounfar
Publikováno v:
Pharmaceutical Biology
Pharmaceutical Biology, Vol 58, Iss 1, Pp 257-264 (2020)
Pharmaceutical Biology, Vol 58, Iss 1, Pp 257-264 (2020)
Context: Curcumin, the active component of Curcuma longa L. (Zingiberaceae), exhibits a wide variety of biological activities including vasodilation and anti-inflammation. Objective: The relaxant effect of curcumin in tracheal smooth muscle (TSM) was
Autor:
Aleksandra Novakovic, Guo-Wei He, Dragoslav Nenezic, Predrag Milojevic, Ivan Stojanovic, Qin Yang, Vladimir Kanjuh, Marija Marinko, Goran Jankovic
Publikováno v:
Journal of Pharmacological Sciences, Vol 142, Iss 3, Pp 101-108 (2020)
Journal of Pharmacological Sciences
Journal of Pharmacological Sciences
Cardioprotective abilities of procyanidins, might, at least in part, attribute to their vasodilator properties. The present study was undertaken to assess the vasorelaxant effect of procyanidin B2 on isolated human saphenous vein (HSV) and its underl
Publikováno v:
Pharmacological Reports
Pharmacological Reports, Inst. of Pharmacology, Polish Acad. of Sciences, 2019, 71, pp.659-668. ⟨10.1016/j.pharep.2019.03.004⟩
Pharmacological Reports, Inst. of Pharmacology, Polish Acad. of Sciences, 2019, 71, pp.659-668. ⟨10.1016/j.pharep.2019.03.004⟩
Sildenafil (PDE5-inhibitor) and alprostadil (PGE1) are used in combination clinically for the management of some cases of erectile dysfunction. Despite the roles of prostaglandins (PG) and nitric oxide (NO) pathways in contractility of bladder smooth
Autor:
Yusuke Nakahashi, Sayano Fukushima, Masashi Kohno, Yukihide Koyama, Moriyoshi Oji, Tomio Andoh, Hidemasa Iwakura, Hiroyuki Oshika
Publikováno v:
BMC Anesthesiology, Vol 19, Iss 1, Pp 1-8 (2019)
BMC Anesthesiology
BMC Anesthesiology
Background We previously demonstrated that lubrication of an endotracheal tube (ETT) cuff with K-Y™ jelly strongly and significantly inhibited the increase in cuff pressure during nitrous oxide (N2O) exposure in vitro. However, in our previous stud
Publikováno v:
Canadian journal of physiology and pharmacology. 100(1)
Acitretin is a member of vitamin A-derived retinoids, and its effect on vascular smooth muscle had not yet been studied. The aim of this study is to investigate the effect of acitretin, a retinoid, on vascular smooth muscle contractility. Thoracic ao
Autor:
Peter B. Senese, Eric Zanelli, Kristian Agmund Haanes, Joseph Kovalchin, Ad J.J.C. Bogers, Antoinette MaassenVanDenBrink, Carlos M. Villalón, Alejandro Labastida-Ramírez, Antoon J. van den Bogaerdt, Kirk W. Johnson, Laurent Meeus, Eloísa Rubio-Beltrán, Michael R Gralinski, A.H. Jan Danser
Publikováno v:
British Journal of Pharmacology
British Journal of Pharmacology, 176(24), 4681-4695. Wiley-Blackwell
British Journal of Pharmacology, 176(24), 4681-4695. Wiley-Blackwell
Background and Purpose: Triptans are 5-HT1B/1D receptor agonists (that also display 5-HT1F receptor affinity) with antimigraine action, contraindicated in patients with coronary artery disease due to their vasoconstrictor properties. Conversely, lasm